News • Oncology
Potential new target for cancer treatment
Inhibition of the enzyme RIOK1 could stop the growth of tumors and the development of metastases
Metastases
News • Oncology
A clue to where cancer metastases are born
Even in remission, cancer looms. Former cancer patients and their doctors are always on alert for metastatic tumors. Now scientists at The Scripps Research Institute (TSRI) have discovered why some cancers may reoccur after years in remission.
News • Cancer follow-up
Machine learning to help radiologists
Physicians have long used visual judgment of medical images to determine the course of cancer treatment. A new program package from Fraunhofer researchers reveals changes in images and facilitates this task using deep learning. The experts will demonstrate this software in Chicago from November 27 to December 2 at RSNA, the world’s largest radiology meeting.
Article • CEUS
Only convincing with contrast
Contrast enhanced ultrasound is part of clinical routine and makes a substantial contribution towards increasing the significance of tissue and organ diagnosis with ultrasound for difficult cases.
News • Breast cancer
A small implanted device could improve survival
A small device implanted under the skin can improve breast cancer survival by catching cancer cells, slowing the development of metastatic tumors in other organs and allowing time to intervene with surgery or other therapies. These findings suggest a path for identifying metastatic cancer early and intervening to improve outcomes.
News • Oncology
Loophole for cancer cells
Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body. To do so, they have to pass through the walls of small blood vessels. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and…
News • Antitumor
Antibody slows tumor growth and metastasis
Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.
News • The Amazing Race
Cancer cells travel together to forge ‘successful’ metastases
There’s apparently safety in numbers, even for cancer cells. New research in mice suggests that cancer cells rarely form metastatic tumors on their own, preferring to travel in groups since collaboration seems to increase their collective chances of survival, according to researchers at Johns Hopkins.
News • Oncology
Easier Detection of Colorectal Cancer
Chemists at Caltech have developed a new sensitive technique capable of detecting colorectal cancer in tissue samples—a method that could one day be used in clinical settings for the early diagnosis of colorectal cancer.
News • Oncology
Breast tumor stiffness and metastasis risk linked by molecule’s movement
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have discovered a molecular mechanism that connects breast tissue stiffness to tumor metastasis and poor prognosis. The study may inspire new approaches to predicting patient outcomes and halting tumor metastasis.
Deadly dance between nerves and cancer cells
In certain types of cancer, nerves and cancer cells enter an often lethal and intricate waltz where cancer cells and nerves move toward one another and eventually engage in such a way that the cancer cells enter the nerves.
Blood vessel lining cells control metastasis
Scientists from the German Cancer Research Center in Heidelberg and from the Medical Faculty Mannheim of Heidelberg University treated mice with a combination of a low-dose metronomic chemotherapy and an antibody against Ang-2, a regulatory protein of the blood vessel lining cells. The treated animals had significantly less metastases.
Article • Oncology
Deepening knowledge of the cancer genome
The term ‘cancer’ describes more than 200 different diseases and every single one needs to be clearly understood and requires, ideally, individual treatment. To do this we need to deepen our understanding the cancer genome. Report: Anja Behringer
Oral vaccination against pancreatic tumours
The world’s first gene cancer therapy study of an innovative oral vaccine is underway at the Surgical Clinic of Heidelberg University Hospital.