Breast cancer

News • Oestrogen-receptor positive, HER2-negative

Test determines most effective treatment for breast cancer

A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK. The test was successful in predicting whether chemotherapy would be beneficial for patients with the most common type of breast cancer (oestrogen-receptor positive, HER2-negative),…

News • Ten-year trial results

Radiotherapy reduces recurrence of early, hormone-driven breast cancer

Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment, according to results from a trial that has followed 869 women for ten years. New findings from the 8 A trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG), presented at the ESTRO 38 conference,…

News • Two years earlier

Breast cancer: blood test could detecting relapse earlier

Research has revealed that a new blood test is able to detect disease relapse up to two years earlier than imaging in patients with early-stage breast cancer. The research, carried out by the University of Leicester and Imperial College London and funded by Cancer Research UK, showed that the blood test was able to detect 89 per cent of all relapses, on average 8.9 months quicker than imaging.

News • Breast healthcare

FDA advances landmark policy changes to modernize mammography services

The U.S. Food and Drug Administration (FDA) announced important new steps to modernize breast cancer screening and help empower patients with more information when they are considering important decisions regarding their breast health care. For the first time in more than 20 years of regulating mammography facilities, the agency is proposing amendments to key regulations that would help improve…

News • Hormones

Stress accelerates breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones.

From technology into innovation, from innovation into care

Fujifilm is a pioneer in digital radiography technology since the early 1980s: since then we have continuously been developing innovative technologies, creating products that deliver greater benefits and improved care to both customers and patients. In the breast screening segment, Fujifilm's strong commitment to continuous technology evolution and a clear commitment in providing innovative…

News • Under pressure

Breast tissue stiffening promotes cancer development

A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells. The work could inspire new approaches to…

News • Cancer stem-like cells

Important signaling pathway in breast cancer revealed

In breast cancer, one of the most common cancers in women, tumors contain a small amount of so-called cancer stem-like cells (CSCs). Being able to eliminate breast-cancer stem-like cells in a targeted way is essential for developing successful therapies — conventional treatments, such as chemotherapy or radiotherapy followed by drug intake, do not target CSCs. A better understanding of the…

News • Hot helper

Can oolong tea prevent breast cancer?

In a recent study published in the journal Anticancer Research, Saint Louis University scientists, together with a visiting scientist from Fujian Medical University in China, have discovered evidence that oolong tea can lead to DNA damage of breast cancer cells and inhibit the growth and progression of tumors in the lab, potentially offering a non-toxic strategy to prevent breast cancer. The…

Article • Breast and skeletal health

AI is proving pivotal in women’s health solutions

Pete Valenti, Hologic’s division president of breast and skeletal health solutions, talks about how AI is driving innovation in breast health technology. Underpinning that evolution more recently has been the acquisition of two organisations – digital specimen radiography specialists Faxitron Bioptics and BioZorb marker manufacturer Focal Therapeutics.

News • breast cancer

System images molecular features of cancer tissue in real-time

A team of University of Illinois at Urbana-Champaign researchers led by Bioengineering Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly after it was surgically removed from a patient in the operating room. The researchers achieved this using a new portable optical imaging system developed in Boppart's lab.

Article • Immuno-oncological biomarkers

Seeking to augment the value of tumour infiltrating lymphocytes

Measuring tumour infiltrating lymphocytes (TILs) is gaining importance in immunotherapy, but other variables must also be considered to boost prognosis and prediction accuracy, a leading pathologist argued at EBCC 11 last March in Barcelona. When it comes to prognosis and prediction for immunotherapy, a potentially new variable is emerging – TILs – white blood cells that have left the blood…

News • Benefits of childbirth

Breast cancer: Pregnancy gives (delayed) protection

In general, women who have had children have a lower risk of breast cancer compared to women who have never given birth. However, new research has found that moms don’t experience this breast cancer protection until many years later and may face elevated risk for more than 20 years after their last pregnancy. Scientists at the National Institutes of Health, along with members of the…

News • Pregnancy

Giving birth raises risk of breast cancer in younger women

Younger women who have recently had a child may have a higher risk of breast cancer than their peers of the same age who do not have children, according to a large-scale analysis co-led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher. The findings, published in the Annals of Internal Medicine, may seem contrary to conventional wisdom that childbirth is…

Article • New Italian study results

Pre-operative MRI endorsed for breast cancer

MRI offers unequalled sensitivity and specificity in breast cancer detection. Yet, it is poorly accepted preoperatively. Recently, eminent radiologist Francesco Sardanelli, professor for radiology at Milan University and Chief of Radiology at the IRCCS Policlinico San Donato in Italy, unveiled preliminary results that could further MRI acceptance among multidisciplinary teams.

News • Machine learning

Training a computer to classify breast cancer tumors

Using technology similar to the type that powers facial and speech recognition on a smartphone, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have trained a computer to analyze breast cancer images and then classify the tumors with high accuracy. In a study published in the journal NPJ Breast Cancer, researchers reported they used a form of artificial…

News • Nanoparticle therapy

Putting a target on breast cancer

The complex structure of breast tumours makes treatment a medical challenge. A promising, novel selenium-based breast cancer nanoparticle therapy by the Austrian Centre of Industrial Biotechnology (acib) together with other partners in the EU-project Neosetac could change that: It has proved to boost the active agent delivery and assure it's active only in the target tissue while also bringing…

News • Research

3D mammography detected 34% more breast cancers in screening

After screening 15 000 women over a period of five years, a major clinical study in Sweden has shown that 3D mammography, or breast tomosynthesis, detects over 30% more cancers compared to traditional mammography – with a majority of the detected tumours proving to be invasive cancers.

News • BIA-ALCL

Breast implant cancer risks: are women aware?

Breast surgeons across the UK must ensure women are aware of BIA-ALCL, a non-Hodgkin’s lymphoma that is associated with implants; and more responsibility must be taken to diagnose and report cases, surgeons attending the 2018 London Breast Meeting have warned. Hundreds of breast specialists from around the world met at the Royal College of Physicians for the four-day conference this autumn,…

Article • Cancer screening

What women should know about breast density

Driving breast cancer screening compliance is an essential part of improving clinical outcomes, and one way to do this is to educate women about their breast density, advises Tracy Accardi, Hologic’s Global Vice President of Research and Development for Breast Health & Skeletal Solutions.

Article • Going digital

DBT could boost breast screening

Tomosynthesis is under international review, with a surprising number of enticing studies carried out in Northern European countries, among them one headed by Professor Sophia Zackrisson at Lund University, Sweden. In our interview, she not only revealed surprising trial results, but also shared her thoughts on practical implementation and unusual speed-reading methods. ‘Our institute’s…

News • Innovation

New portable ultrasound system is available

Hologic’s new Viera portable breast ultrasound system is now available for purchase in the U.S. and Europe. Delivering exceptional image quality at the point of care, the Viera wireless ultrasound scanner provides physicians with the opportunity for earlier diagnoses and an optimized clinical workflow – all at a fraction of the cost of larger, mid-tier cart systems.

Article • Heard at the EBCC11

Identifying circulating tumour cells with liquid biopsy

Liquid biopsies can increasingly help diagnose and monitor breast cancer, and tracking circulating tumour cells (CTC) in metastatic patients could prove effective in these applications and treatment planning. Efforts are currently underway to demonstrate CTC clinical use and much can be learned from completed studies in prostate cancer, speaker Michail Ignatiadis MD PhD highlighted in a dedicated…

Article • To-Be for tomo

Two-part trial studies tomosynthesis benefits

The UNESCO World Heritage City Bergen is seen as the gateway to the fiords of Norway. However, for radiologists the city offers an even more interesting attraction than Scandinavian landscapes. Bergen features one of the largest randomised control trials to compare digital breast tomosynthesis (DBT) with digital mammography (DM): the To-Be trial. Professor Solveig Hofvind, head of BreastScreen…

Study confirms: Scalp Cooler prevents alopecia

‘Scalp cooling successfully prevents alopecia in breast cancer patients undergoing anthracycline or taxane-based chemotherapy’, according to the latest clinical data published in The Breast. The paper, written by clinicians from the Berlin Oncology Center, Germany, revealed that 71% of women who took part on the study retained their hair as a result of using the Paxman Scalp Cooler. Scalp…

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