Bowel cancer survival rates could be improved if chemotherapy drugs were delivered via tiny nanoparticles to the diseased organs rather than oral treatment. That’s the finding from Indian and Australian scientists who have undertaken the first study, using nanoparticles to target bowel cancer, the third most common cancer in the world and the second most deadliest.
A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.
Robotics, AI, and machine learning can make spinal surgery more accurate, efficient, and safer, thereby reducing costs, patient recovery time, and radiation exposure.
A test which uses artificial intelligence (AI) to measure proteins present in some patients with advanced bowel cancer could hold the key to more targeted treatment, according to new research. A team at the University of Leeds collaborated with researchers at Roche Diagnostics to develop the technique, which will help doctors and patients to decide on the best treatment options.
For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment can cause severe, acute inflammation of the esophagus (esophagitis) in about one in five patients, requiring hospitalization and placement of a feeding tube. A team of radiation oncologists at Mass…
A team led by a clinical academic at University College London (UCL) has outlined the mechanism behind rare cases of blood clots and low platelets seen in patients who have had the Oxford/AstraZeneca vaccine. The new study, published in the New England Journal of Medicine, highlights the importance of rapidly spotting this new syndrome, known as vaccine-induced thrombosis and thrombocytopenia…
What happens when patients can no longer breathe on their own and need to be supported by machines? How far does infected air spread throughout a room? And what safety precautions do medical and nursing staff need to take? Respiratory specialists Dr. Dominic Dellweg and Dr. Jens Kerl together with Dr.-Ing. Conrad Völker, Amayu Wakoya Gena, and Dr. Hayder Alsaad from the Department of Building…
The world is still failing to develop desperately needed antibacterial treatments, despite growing awareness of the urgent threat of antibiotic resistance, according to a new report by the World Health Organization. WHO reveals that none of the 43 antibiotics that are currently in clinical development sufficiently address the problem of drug resistance in the world’s most dangerous bacteria.…
Genetically enhancing a patient's immune cells by adding therapeutic genes to them outside the body is regarded as a promising new treatment approach in oncology. However, the production of these therapeutic cells using viruses is not only expensive but time-consuming. Researchers at the German Cancer Research Center (DKFZ) have developed an innovative non-viral vector that can efficiently…
Researchers at the University of Oxford report that the risk of the rare blood clotting known as cerebral venous thrombosis (CVT) following Covid-19 infection is around 100 times greater than normal, several times higher than it is post-vaccination or following influenza. The study authors, led by Professor Paul Harrison and Dr Maxime Taquet from Oxford University’s Department of Psychiatry and…
Researchers from the Canadian University Healh Network (UHN) have developed and validated a deep learning model to predict a patient's long-term outcome after receiving a liver transplant. First of its kind in the field of Transplantation, this model is the result of a collaboration between the Ajmera Transplant Centre and Peter Munk Cardiac Centre (PMCC). The study, published in Lancet Digital…
Researchers running the Com-Cov study, launched in February to investigate alternating doses of the Oxford-AstraZeneca vaccine and the Pfizer vaccine, announce that the programme will be extended to include the Moderna and Novavax vaccines in a new study.
What’s in a name? In the case of Asensus Surgical, Inc., previously known as TransEnterix, Inc., the recent rebranding doubles as a mission statement for the manufacturer of surgical robotics systems: The initial ‘A’ stands for artificial intelligence and augmented surgery, reflecting the company’s emphasis on new technologies designed to enhance the operator’s cognition (‘sensus’…
A new report shows how palliative and end of life care in the UK was compromised by shortages of PPE, essential medicines, and equipment, because these services were not seen as ‘frontline NHS’ in the pandemic. Better End of Life – a collaboration between Marie Curie, Hull York Medical School, University of Hull, King’s College London Cicely Saunders Institute, and the University of…
At a cost of $38 billion a year, an estimated 5.3 million people are living with a permanent disability related to traumatic brain injury (TBI) in the United States today, according to the Centers for Disease Control and Prevention. The physical, mental and financial toll of a TBI can be enormous, but new research from the University of Georgia provides promise. In a new study, researchers at…
Thanks to extended permissions obtained from the Civil Aviation Authority (CAA) in Sweden, autonomous drone company Everdrone will soon provide 200,000 people in Sweden with access to emergency medical deliveries of Automated External Defibrillators (AEDs) by drone as Everdrone expands operations outside the Gothenburg region.
With interventional procedures becoming more and more complex the demands on the interventionalists are also increasing. Endovascular simulators allow practical angiography training. In December 2020, the University Hospital Essen, Germany, was the first European facility to install Mentice’s VIST G7+. Professor Dr Jens Theysohn, senior physician at the Institute of Diagnostic and…
Intrahepatic cholangiocarcinoma (ICC) develops within the liver. With one to two cases per 100,000 inhabitants in Germany, ICC is one of the rare diseases overall, but it is the second most common liver cancer. The aggressive bile duct tumour remains clinically inconspicuous for a long time, so that it is often only detected late. Because the tumour also only responds to chemotherapy to a limited…
International genomics research led by the University of Leicester has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes. Mesothelioma is caused by breathing asbestos particles and most commonly occurs in the linings of the lungs or abdomen. Currently, only seven per cent of people survive five years after diagnosis, with a prognosis…
Tumor vaccines can help the body fight cancer. Mutations in the tumor genome often lead to protein changes that are typical of cancer. A vaccine can alert the patients' immune system to these mutated proteins. For the first time, physicians and cancer researchers from Heidelberg and Mannheim have now carried out a clinical trial to test a mutation-specific vaccine against malignant brain tumors.…
More than four in five (86%) people who were unsure or said no to a Covid-19 vaccine in December 2020 would now take one, or have already been vaccinated, finds the latest research by the Virus Watch study conducted by University College London (UCL).
Lung tumors are home to immune cells that affect their growth and resistance to treatment. Looking at neutrophils, scientists led by EPFL have discovered that the key might lie in the cells’ ability to metabolize glucose, opening an entirely new target for improving radiotherapy.
Researchers from Cleveland Clinic’s Florida Research and Innovation Center (FRIC) have identified a potential new target for anti-COVID-19 therapies.
Even as vaccines are becoming more readily available, protecting against the asymptomatic and pre-symptomatic spread of the virus (SARS-CoV-2) that causes Covid-19 is key to ending the pandemic, say two infectious disease experts at the Georgetown University Medical Center. In their Perspective, “SARS-CoV-2 Transmission Without Symptoms,” published in the journal Science, they make the case…
‘Hello Tessa. Do you know what I’m doing today?’ a fragile, elderly woman asks tentatively. The small robot she’s addressing has a decorative plant on its head and is wearing a jacket. This is not a funny fantasy. Tessa has proved ‘her’ usefulness and acceptability. The little robot results from a year-long pilot project recently completed in the Netherlands by the Groene Kruis…