Laboratory

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Article • Antimicrobial stewardship

A diagnostic marker reduces antibiotics use

Since 2009, as part of diagnostic and antimicrobial stewardship strategies, Hampshire Hospitals National Health Service (NHS) Trust has used serum procalcitonin (PCT) – an innovative and highly specific marker to diagnose clinically relevant bacterial infections and sepsis. Report: Mark Nicholls

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Interview • Mass Spectrometry

Connected components are not enough

Bringing liquid chromatography and tandem mass spectrometry (LC-MS/MS) testing into clinical laboratories has been a slow process but continues to show promise to help improve patient care. The medical device industry is on the edge of fundamental breakthroughs that can help drive the adoption into more mainstream clinical laboratories. We recently sat down with Dr Bori Shushan, Mass Spectrometry…

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Article • Research

Genetic alterations

This article discusses examples of applications of genetic analyses in coagulation disorders and haematological and oncological diseases. Professor Christine Mannhalter highlights the impact changes have on the occurrence and severity of diseases and their influence on therapy response. Report: Christine Mannhalter

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A chip placed under the skin for more precise medicine

Several EPFL laboratories are working on devices allowing constant analysis over as long a period as possible. The latest development is the biosensor chip, created by researchers in the Integrated Systems Laboratory working together with the Radio Frequency Integrated Circuit Group. Sandro Carrara is unveiling it today at the International Symposium on Circuits and Systems (ISCAS) in Lisbon.

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Article • Mutations

Dutch scientists build colon cancer progression model

Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.

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Article • Nosocomial infections

Hygiene begins between the ears

"Infection prevention and control is a matter of awareness and continuous education," says Dr Ernst Tabori, Medical Director of the German Consulting Centre for Hospital Epidemiology and Infection Control (BZH), at the University Hospital Freiburg, specialises in building hygiene in hospitals and outpatient healthcare facilities, as well as surgical units. Report: Anja Behringer

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Article • Human resources

A pathology workforce fit for the future

The UK pathology sector faces numerous challenges as it strives to create a future medical laboratory workforce. As in many divisions of the National Health Service (NHS), this area has an ageing population yet must evolve against a backdrop of fast-developing technologies, emerging science, financial constraints and the challenge of working in tandem with the private sector. Report: Mark…

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Sponsored • POCT

This market will boom

The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…

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Article • Excellence Award

ESCMID honours Médecins Sans Frontières

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) today issued a special excellence award for outstanding achievement to Médecins Sans Frontières (MSF). The award was bestowed in Copenhagen at ESCMID’s annual congress, on behalf of all its members, in light of the charity’s huge contribution to global health over the last 40-years, and in special recognition of…

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Sponsored • Automation

Scottish NHS group endorses automation

It’s thumbs up for Siemens Healthcare Diagnostics’ Aptio Automation, following a two-year deployment by Dundee-based National Health Service (NHS) Dundee, the first north European healthcare organisation to use the system to consolidate formerly siloed biochemistry, immunology, haematology and haemostasis testing onto a single automation track.

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Article • DRUG resistance

Cut prescriptions and choose treatments wisely!

Prescribing antibiotics for a viral infection with fever, a cold and a cough? There is no point! This is the best-known example of over-use in medicine. There are also numerous examples of diagnostic procedures and therapies that are pointless, yet still being doled out in surgeries and hospitals – sometimes even harming a patient. This is set to change, according to the German Society of…

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Article • Preamble

Keeping up with an ever-evolving science

Expecting 10,000 participants, prior to the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Copenhagen, Denmark (25-28 April) its Programme Director, Professor Winfried V Kern MD, was keen to point out: ‘The findings and recommendations that emerge from this vibrant platform each year have, in the past, had a tremendous impact not only on guidelines and best…

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Article • IVD regulations

'We will need a lot more regulators'

The proposed EU draft IVD regulation looks set to have major implications for IVD manufacturers and laboratory-developed tests (LDTs). Replacing a current system that is inflexible, unresponsive and does not effectively protect patients, the new regulation will apply directly to all 28 EU countries and govern the manufacture and marketing of in vitro diagnostic devices (IVDs).

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Article • Nosocomial infections I

Microbes vs. viruses

In European acute care hospitals, on any given day, an estimated 80,000 patients – roughly six percent of all patients – receive antimicrobial treatment to fight a healthcare associated infection (HAI), according to the European Centre for Disease Prevention and Control (ECDC). Report: Walter Depner

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