Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner.
A new technique – single cell RNA-sequencing – may offer answers and hope to the 200,000 mothers and partners affected by pregnancy loss in the UK every year.
Arteriogenesis is a critical event – not only during development but also in adult life. Many Cardiovascular life-threatening events could be overcome by inducing the formation of new arteries. A team of scientists led by Ralf Adams from the Max Planck Institute for Molecular Biomedicine has developed a genetic approach in mice to uncover molecular mechanisms of arterial growth.
Social isolation has been linked to a wide range of health problems, as well as a shorter lifespan in humans and other animals. In fact, during a U.S. Senate hearing on aging issues this spring, a representative for the Gerontological Society of America urged lawmakers to support programs that help older adults stay connected to their communities, stating that social isolation is a “silent…
Scientists from the University of Würzburg successfully elucidated new details about a circuit regulating platelet biogenesis. These important findings could contribute to a better understanding of the mechanism leading to bleeding disorders.
A team of researchers has pinpointed a sugar modification in cells that spurs the spread of skin cancer. Its findings spotlight a target in the battle against melanoma.
Following its success in establishing reference methods and values for a range of simple molecules, International Federation of Clinical Chemistry and Laboratory Medicine’s Scientific Division takes on the challenge of harmonization for hormones and endocrine tests.
In our interview with the physician Dr. Fabian Berger, we want to know about the advantages of molecular biological procedures compared to conventional C. difficile diagnostics.
SpeeDx Pty, Ltd. announced an agreement with Cepheid for distribution of its PlexPCRTM and ResistancePlusTM molecular diagnostic products in key markets throughout Europe. The agreement, covering Germany, France, Italy, and the UK, will increase coverage for the market-leading ResistancePlus MG test, the first CE-IVD test for Mycoplasma genitalium to combine detection with testing for…
Study reveals the surprising role of omega-3 fatty acids in keeping the blood-brain barrier closed
Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, there’s no way to accurately predict which patients might lose vision most rapidly. Now, studying mice, rats and fluid removed from the eyes of patients with glaucoma, researchers at…
European Hospital reports a new approach in molecular diagnostics introduced during the IASLC World Conference in Vienna.
A new molecular diagnostics system is revolutionising analysis of hospital samples across an area of northern Italy. The Greater Romagna Area Hub Laboratory has recently installed the Beckman Coulter DxN VERIS Molecular Diagnostics System and is already reporting improved workflow and quicker turnaround time for results.
Curetis N.V. and the European Investment Bank (EIB) today announced that the EIB granted Curetis a EUR 25 million senior, unsecured loan. The financing is the first growth capital loan under the European Growth Finance Facility (EGFF). It is backed by a guarantee from the European Fund for Strategic Investments (EFSI).
BBI Solutions has launched Morffi, a novel conjugate blocking technology that enhances signal intensity and improves the sensitivity of lateral flow immunoassaysThe technology, developed in-house by BBI Solutions scientists, improves the limit of detection of an assay, providing an increase in sensitivity of up to ten times and a faster time to result.
When one cell divides into two - that is how all forms of life are propagated - the newly born daughter cells have to be equipped with everything they will need in their tiny lives. Most important of all is that they inherit a complete copy of the genetic information from their mother cell. If this is not the case because a wrong number of chromosomes – on which the genetic information is…
UK researchers have identified a new approach, which could make it easier to identify fatty plaques that could cause heart attacks or a stroke.
Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed. For many years, this patient group will be examined frequently and during this time many get new tumours; some cases develop aggressively making it necessary to remove the bladder or receive…
The unusual electronic properties of some superconducting materials permit lossless and dense electrical currents at very low temperatures, even in high magnetic fields. Conductors made of these materials are thus ideal for winding coils to generate very high magnetic fields, which are essential for a number of applications like magnetic medical imaging, MR spectroscopy for the analysis of…
As one of medicine’s largest challenges, viral infections often escape vaccines due to their natural ability to mutate rapidly and develop drug resistance easily. Many viruses, such as Zika, Ebola and dengue fever, have grown into major global health epidemics with great human and economic toll. IBM Research and Singapore’s Institute of Bioengineering, Nanotechnology (IBN) announced they have…
On top of the meaning and mystery that humans heap on the heart, it is first and foremost, a muscle. And one that beats about once a second for a person’s entire life, with no rest. Given its vital importance, it’s ironic researchers have only recently made direct observations of its subcellular parts in motion.
Since the introduction of targeted therapies in oncology the task of the pathologist has expanded beyond histological diagnostics: today, the pathologist analyses tumour tissue samples to establish a molecular profile with tumour cell characteristics – which in turn become the targets of medication.
As medical professionals search for new ways to personalize diagnosis and treatment of disease, RPB-supported researchers at the University of Iowa have already put into practice what may be the next big step in precision medicine: personalized proteomics.
A team of researchers at the MedUni Vienna has, in collaboration with the AIT Austrian Institute of Technology, developed two new PET tracers that allow the activity of drug transporters at the blood-brain barrier to be measured. The studywas able to demonstrate that people with a genetic polymorphism in a transporter gene have lower transporter activity at the blood-brain barrier, which can lead…
Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal.