The equivalent of HD or Ultra-HD for home television and video is now entering the world of medicine. Although 4K technology with its high-resolution display quality is already used in radiology, there are areas that do not yet benefit from this advanced technology.
No self-respecting TV crime series is without a pathologist – but the fictitious pathologist who incessantly solves crimes has little to do with reality.
Since the introduction of targeted therapies in oncology the task of the pathologist has expanded beyond histological diagnostics: today, the pathologist analyses tumour tissue samples to establish a molecular profile with tumour cell characteristics – which in turn become the targets of medication.
Imaging research is one step closer to giving clinicians a way to do high-resolution scans of malignant cells in order to diagnose cancer and help identify useful therapies. If this technology were to prove successful in clinical studies, it might change how anatomic pathologists and radiologists diagnose and treat cancer.
Although tuberculosis (TB) is commonly thought of as being a disease that mainly affects nineteenth century poets and Victor Hugo characters, it is still the second-most common cause of mortality from an infectious disease in the world, killing nearly three people every minute.
Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these findings, published in The American Journal of Pathology, provide unprecedented, clinically-relevant insights about how MERS progresses, they…
Post mortems are now rarely carried out within UK hospitals – according to a study that examined all acute NHS Trusts within England, NHS Boards in Scotland and Wales and Social Care Trusts in Northern Ireland, and found that the process has disappeared completely in around a quarter (23%) of NHS trusts. In 2013, the average autopsy rate (percentage of adult in-patient deaths that undergo…
The field is so new that the annual Digital Pathology Congress (3-4 December in London) was held for only the second time. Yet, Philips Healthcare could announce a world-first – in partnership with the Netherlands-based LabPON, the company has created the first clinical pathology laboratory to be completely converted to digital diagnosis.
Collaborating with colleagues locally and globally using telepathology can be successful for facilities both financially and clinically, says Dr. Liron Pantanowitz, director of pathology informatics at University of Pittsburgh Medical Center (UPMC). Pantanowitz, who also serves as a consultant to Onyx, a company that provides digital pathology technology and is joint venture between GE Healthcare…
Increasing requirements for specialisation and diagnostic quality in pathology on the one hand and the importance of pathology findings for treatment planning on the other hand call for new solutions in pathomorphological diagnostics. One important starting point is the fast-paced opportunity for digitalisation along with communication systems which facilitate the storage and transfer of large…
The Swedish healthcare Region Östergötland is making a full commitment to digital pathology by investing in a solution from Sectra for storage, review and sharing of digital pathology images. The aim of the region’s investment is more rapid care for cancer patients, in which pathology has a key role in diagnosis and treatment.
When a pathogen invades the body, specific cells in the human immune system are ready to take immediate action in order to destroy it. The molecular characteristics of these killer cells were unknown until recently. Now, for the first time, a team from the Technical University of Munich (TUM) has managed to create a molecular profile of the protective cells. By studying these immune cells from…
Automated image analysis shows significant potential within histopathology to help identify novel and subtle prognostic features. UK expert Dr Peter Caie also believes such image analysis can turn aspects of histopathology from a traditionally semi-quantitative field into a fully quantifiable and standardised science. However, he also points out that challenges remain before the full potential is…
Computer-aided diagnosis could soon play a greater role in digital pathology. Dr Jeroen van der Laak, an Assistant Professor in Digital Pathology at Radboud University, believes a breakthrough that would increase the speed and accuracy of diagnoses and prognoses is closer than many observers think Report: Mark Nicholls
A national digital pathology system across Denmark has helped to significantly improve efficiency and raise levels of patient safety. It has used advanced computer software systems and created a countrywide database to optimise the assessment of patients’ specimens. Report: Mark Nicholls
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Pathology is the gold standard of prostate diagnostics. Whilst the radiologist makes interpretations based on shadows and grey scale values visible on an image, the pathologist has the ‘fait accompli’ under the microscope. Professor Glen Kristiansen, Director at the Institute for Pathology at the University Hospital Bonn, explains why image-guided biopsies also make sense from the…
What you see is what you get - unfortunately, this doesn’t always apply in cancer imaging. Why is it that something which looks conspicuous on an image later turns out not to be a tumour? Why, on the other hand, are things overlooked that later turn out to be cancer? Pathological findings are extremely important to help improve diagnostic precision in radiology. Both disciplines therefore…
University Hospital Utrecht (UMCU) in the Netherlands has invested in a solution from Sectra for storing, viewing and sharing digital pathology images. The solution enables pathologists to review cases for primary diagnostics digitally. This new opportunity significantly increases workflow efficiency and offers enhanced collaboration between pathologists and radiologists at the hospital enabling…
Digitizing pathology is not just a transformation of technology, the major change and benefits lies in the change to a more efficient workflow – enabled by the new technology.
Urinary tract infections (UTIs) are common, and widespread antibiotic resistance has led to urgent calls for new ways to combat them. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that an experimental drug that stabilizes a protein called HIF-1alpha protects human bladder cells and mice against a major UTI…
The ESCMID Study Group for Forensic and Postmortem Microbiology will create a new network of microbiologists, virologists, anthropologists and archaeologists working in the field of forensic medicine. Professor Amparo Fernandez-Rodriguez, from the National Institute of Toxicology and Forensic Sciences, Madrid, is the head of ESGFOR and stresses the importance of this group in facilitating…
Each year, approximately 1.6 million women in the USA have breast biopsies to diagnose or rule out cancer. Pathological diagnosis is considered the gold standard – how accurate are these diagnoses? Report: Cynthia E. Keen
The UK pathology sector faces numerous challenges as it strives to create a future medical laboratory workforce. As in many divisions of the National Health Service (NHS), this area has an ageing population yet must evolve against a backdrop of fast-developing technologies, emerging science, financial constraints and the challenge of working in tandem with the private sector. Report: Mark…
In 1995 Claudia and Robert Karl risked self-employment in a sector already dominated by experts. Those manufacturers, however, sold standardised products. The Karls, with backing from a stainless steel producer, decided to produce tailor-made solutions to fit customers’ needs. To that end they attended international medical equipment exhibitions from Dubai through to Malaysia. Today, Claudia…