Article • Osteoporosis
Vienna peaks in breast cancer research
‘Today Vienna is one of the top addresses with regard to breast cancer research,’ Professor Michael Gnant proudly reports – and he certainly knows what he is talking about.
Breast cancer
Article • Elastography
Using the entire ultrasound arsenal
Although breast elastography entered clinical practice many years ago, a large number of breast radiologists are still unaware of its benefits and have not become familiar with its principles.
News • Chemotherapy
Precision medicine test helps guide breast cancer patients’ decision
One of the earliest widespread applications of precision medicine in cancer care is helping patients and physicians decide whether chemotherapy is needed, a new study finds.
Imaging community to celebrate International Day of Radiology
Radiologists and radiographers all over the world will once again celebrate the International Day of Radiology (IDoR) on November 8, which this year takes breast imaging as its main theme. The IDoR is an initiative of the European Society of Radiology (ESR), the American College of Radiology (ACR) and the Radiological Society of North America (RSNA).
Article • Tomosynthesis
Additional cancer screening for women with dense breasts
Italian-led research has highlighted the value of utilising additional screening technologies to help diagnose breast cancer in some women. Interim analysis from the Adjunct Screening with Tomosynthesis or Ultrasound in Women with Mammography-Negative Dense Breasts (ASTOUND) study has delivered evidence of the potential benefit of adding either ultrasound or tomosynthesis to standard mammograms…
News • Breast cancer
A small implanted device could improve survival
A small device implanted under the skin can improve breast cancer survival by catching cancer cells, slowing the development of metastatic tumors in other organs and allowing time to intervene with surgery or other therapies. These findings suggest a path for identifying metastatic cancer early and intervening to improve outcomes.
Overcoming multidrug-resistant cancer with smart nanoparticles
Multidrug resistance (MDR) is the mechanism by which many cancers develop resistance to chemotherapy drugs, resulting in minimal cell death and the expansion of drug-resistant tumors. To address the problem of resistance, researchers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) at the National Institutes of Health (NIH) have developed nanoparticles that…
News • Counterproductive
Breast tumors evolve in response to hormone therapy
Many breast tumors grow in response to female hormones, especially estrogen. Drugs that reduce estrogen levels in the body often are effective in reducing tumor size and preventing recurrence of the cancer. But some tumors become resistant to these therapies and continue to grow and spread.
News • BRIM
Technology helps ID aggressive early breast cancer
When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful? Researchers at the University of Michigan developed a new technology that can identify aggressive forms of ductal carcinoma in situ, or stage 0 breast cancer, from non-aggressive…
News • Breast cancer
Device allows 3D imaging with less radiation
Preliminary tests have demonstrated that a new device may enable existing breast cancer imagers to provide up to six times better contrast of tumors in the breast, while maintaining the same or better image quality and halving the radiation dose to patients. The advance is made possible by a new device developed for 3D imaging of the breast by researchers at the Department of Energy's Thomas…
News • Breast cancer
Artificial intelligence diagnoses with high accuracy
Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed. A research team from Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS) recently developed…
Microfluidic device tests effects of electric fields on cancer cells
Researchers at Massachusetts Institute of Technology research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells. They observed that a range of low-intensity, middle-frequency electric fields effectively stopped breast and lung cancer cells from growing and spreading, while having no adverse effect on neighboring healthy cells.
News • Mutation
Prevention of genetic breast cancer within reach
An international team led by researchers at the Austrian Institute of Molecular Biotechnology (IMBA) in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. An already approved drug could be quickly available and would then be the first breast cancer prevention drug.
News • Active substance
Promising treatment prospects for invasive breast cancer
Scientists from the University of Zurich have been able to understand for the first time why many cancer cells adapt relatively quickly to the treatment with therapeutic antibodies in invasive forms of breast cancer. Instead of dying off, they are merely rendered inactive. The researchers have now developed an active substance that kills the cancer cells very effectively without harming healthy…
Article • Molecular profile
Revealing cancer at a minuscule level
Since the introduction of targeted therapies in oncology the task of the pathologist has expanded beyond histological diagnostics: today, the pathologist analyses tumour tissue samples to establish a molecular profile with tumour cell characteristics – which in turn become the targets of medication.
News • Research
A pill could improve breast cancer diagnoses
The ongoing debate about breast cancer diagnostics has left many women confused — particularly over what age they should get mammograms and who needs treatment. An issue with current methods is that they often identify lumps but cannot conclusively pinpoint which ones are cancerous. To help resolve this uncertainty, researchers have developed a pill that could improve imaging techniques so that…
First injectable nanoparticle generator to fight breast cancer
A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.
News • Antitumor
Antibody slows tumor growth and metastasis
Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according to a new study published in the February issue of Nature Communications.
Article • Tomosynthesis
Ready to take over?
Results from recent trials are promising: an almost 40% increased breast cancer detection rate from digital breast tomosynthesis (DBT) screening compared to conventional mammography.
News • Research
New Hybrid PET/MRI system improves breast cancer diagnosis
A new EU-funded project HYPMED is developing a ground-breaking imaging method for more accurate detection of breast cancer and a better, more personalised, understanding of its response to therapy.
News • Mammography
Making a safe procedure even safer
In a comprehensive modeling study, researchers from UC Davis and other institutions have found that breast cancer screening with digital mammography poses only a small risk of radiation-induced breast cancer for most women. However, the research showed increased risk for women with large breasts or breast implants, who must often receive extra screening views, increasing their radiation exposure.
Article • Breast cancer screening
Spanish experts clash over benefits and harms
Breast cancer screening has helped to detect cancer in its early stages, but it is unclear how important this contribution is to mortality reduction because treatment has greatly improved. Overdiagnosis and overtreatment remain associated risks that need to be fully assessed for screening to be of real benefit. Leading experts in this field passionately discussed these controversies in a…
News • RSNA 2015
Breast MRI after mammography may identify additional aggressive cancers
Additional breast cancers found with MRI are sometimes larger and potentially more aggressive than those found on mammography, according to a study published online in the journal Radiology.
High-grade DCIS detection rates increase in older women
The mammography detection rate of an early-stage but potentially invasive type of breast cancer rises with age, according to a large new study from Germany published online in the journal Radiology.
News • Toolkit
Microchip helps to visualize breast cancer proteins
A photograph may reveal how something looks, but direct observation can divulge how the objects behave. The difference can mean life or death, especially when it comes to fighting human disease. To help researchers examine exactly how human diseases work at the molecular level, Virginia Tech Carilion Research Institute scientist Deborah Kelly has developed a new set of tools to peer into the…
