Neurology

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News • Artificial nerve response

Computer model simulates sense of touch from the entire hand

Neuroscientists from the University of Chicago have developed a computer model that can simulate the response of nerves in the hand to any pattern of touch stimulation on the skin. The tool reconstructs the response of more than 12,500 nerve fibers with millisecond precision, taking into account the mechanics of the skin as it presses up against and moves across objects.

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News • Neuropathology

Detecting Alzheimer's disease before symptoms emerge

Long before symptoms of Alzheimer's disease become apparent to patients and their families, biological changes are occurring within the brain. Amyloid plaques, which are clusters of protein fragments, along with tangles of protein known as tau, form in the brain and grow in number, eventually getting in the way of the brain's ability to function. These biological changes can be detected early in…

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News • Neurology

New-found brain pathway has implications for schizophrenia treatment

Neuroscientists at Tufts University School of Medicine have discovered a new signaling pathway that directly connects two major receptors in the brain associated with learning and memory – the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR) – which has significance for current efforts to develop drugs to treat schizophrenia.

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News • Neural activity

Movie research results: Our brains are bad at multitasking

The brain works most efficiently when it can focus on a single task for a longer period of time. Previous research shows that multitasking, which means performing several tasks at the same time, reduces productivity by as much as 40%. Now a group of researchers specialising in brain imaging has found that changing tasks too frequently interferes with brain activity. This may explain why the end…

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News • Blood flow control

"Switch" in brain’s capillary network monitors activity

All it takes is the flip of a protein “switch” within the tiny wire-like capillaries of the brain to increase the blood flow that ensures optimal brain function. New research has uncovered that capillaries have the capacity to both sense brain activity and generate an electrical vasodilatory signal to evoke blood flow and direct nutrients to nourish hard-working neurons.

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News • Lab Study

A protein called PERK - Treating progressive supranuclear palsy

The brain disease “progressive supranuclear palsy” (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech. Scientists at the German Center for Neurodegenerative Diseases (DZNE) and the Technical University of Munich (TUM) have now discovered a molecular mechanism that may help in the search…

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News • Stress Research

Chronic stress neurons discovered

A novel population of neurons that are only activated following chronic stress is identified. Today, stress is part of everyday life. However, when stress is chronic it can lead to distressing illnesses such as depression and anxiety disorders. In their latest study, scientists at the Max Planck Institute of Psychiatry in Munich have identified a population of neurons in the hypothalamus that…

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News • Study

Molecular Roots of Alzheimer’s

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

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Article • Computer intelligence

Cognition-guided surgery – a rocky road

Surgery will change – with all the challenges that developments such as Big Data create there are no two ways about it. However, how deep those changes run remains to be seen. In a rather young field of research, scientists look at the ways all components used during surgery can be interlinked. Professor Beat Müller, co-initiator of the project ‘Cognition-Guided Surgery’, explains results…

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News • Stroke Patients

New hope for recovery of hand movement

Stroke patients are starting a trial of a new electronic device to recover movement and control of their hand. Neuroscientists at Newcastle University have developed the device, the size of a mobile phone, which delivers a series of small electrical shocks followed by an audible click to strengthen brain and spinal connections.

News • Neurology

“Stroke clearly is a brain disease”

“The medical rationale for stroke being a disease of the brain is overwhelming.” This is the key message of an urgent appeal launched by leading neurology experts in The Lancet.1 The authors are making public their concern about the classification of stroke in the draft revision of the “International Statistical Classification of Diseases and Related Health Problems” (ICD) after an…

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