Scientists uncover nuclear process in the brain
NIH-funded study highlights the possible role of glial brain cells in neurological disorders.
Tetris can block cravings
Psychologists from Plymouth University and Queensland University of Technology, Australia, found that playing Tetris interfered with desires not only for food, but also for drugs, including cigarettes, alcohol and coffee, and other activities.
News • Bioreactor
Cancer treatment models get real
Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones.
Article • Multimodal imaging
Imaging probe yields double insight
An organic dye that can light up cancer cells for two powerful imaging techniques providing complementary diagnostic information has been developed and successfully tested in mice by A*STAR researchers.
News • Apple
New app to recruit and track patients in clinical study
By providing tools to allow users to be more productive in working with healthcare big data, several Silicon Valley giants hope to increase their presence in medical services. The latest company to enter the field is Apple Computers. In March it announced the availability of ResearchKit, an open-source software framework that turns the iPhone into a research tool.
News • Biomarker
Urine test for early stage pancreatic cancer
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, UK researchers have found. The discovery could lead to a non-invasive, inexpensive test to screen people at high risk of developing the disease.
News • Research
Malaria’s key to the liver uncovered
Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease.
News • Fish pathogen
Toxin from salmonid fish has potential to treat cancer
Pathogenic bacteria develop killer machines that work very specifically and highly efficiently. Scientists from the University of Freiburg have solved the molecular mechanism of a fish toxin that could be used in the future as a medication to treat cancer.
News • Medication
Arthritis drug could be used to treat blood cancer
Scientists at the University of Sheffield have discovered that a common drug given to arthritis sufferers could also help to treat patients with blood cancers.
News • AACC News
Rapid Ebola test could help end lingering outbreak
Research presented at the 2015 AACC Annual Meeting & Clinical Lab Expo will expand on the studies that led to a fingerprick Ebola test becoming the first and only rapid diagnostic for this disease to receive approval from the World Health Organization (WHO). This test could prove vital to breaking Ebola’s grip on West Africa by identifying suspected Ebola cases within minutes, and enabling…
News • Genetic Disorder
How to predict development of autism or psychosis
Doctors and researchers have long known that children who are missing about 60 genes on a certain chromosome are at a significantly elevated risk for developing either a disorder on the autism spectrum or psychosis — that is, any mental disorder characterized by delusions and hallucinations, including schizophrenia. But there has been no way to predict which child with the abnormality might be…
The light of fireflies for medical diagnostics
The lab of Kai Johnsson at EPFL, led by Alberto Schena and Rudolf Griss, were able to add a small chemical tag on the enzyme luciferase, which produces the light of fireflies. The tag detects a target protein, and the luciferase gives out a light signal that can be seen with a naked eye.
Transgender youth have typical hormone levels
Johanna Olson, MD, and her colleagues at Children's Hospital Los Angeles, provide care for the largest number of transyouth in the U.S. and have enrolled 101 patients in a study to determine the safety and efficacy of treatment that helps patients bring their bodies into closer alignment with their gender of identity.
Stopping malaria in its tracks
A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans.
Printing implants with the laser
Whether for individual micro-implants or for micro-implants with medicine depots – additive processes are ideally suited for manufacturing such components. In the project “REMEDIS”, scientists at the Laser Zentrum Hannover e.V. (LZH) have established a highly automated laser melting process to produce or coat implants made of platinum, nickel-titanium (NiTi) or stainless steel.
Article • Science
Alternative routes to immortality
Every time a cell divides, the ends of chromosomes – the threads of DNA residing in the nucleus – shorten a bit. Once the chromosome ends, called telomeres, become too short, cells normally stop dividing. Scientists from the German Cancer Research Center (DKFZ) have now discovered how cancer cells make use of specific DNA repair enzymes to extend the telomeres. In this way, they escape the…
News • Study
Heroin use surges in the US
Use of heroin in the United States has surged dramatically in the past decade, a new study finds. The news follows earlier reports that fatal overdoses from heroin have quadrupled since 2002, suggesting that the country is facing a new epidemic of opiate dependence.
News • Developing Nations
Researchers turn bubble wrap into tiny test tubes
Inexpensive packing material pops up as an alternative to high-cost glass lab equipment for simple diagnostic tests, a potential boon in developing nations.
Article • Therapy
Molecular imaging mines deeper
The view across the Atlantic – it fills Professor Fabian Kiessling, Chair of Experimental Molecular Imaging at the RWTH Aachen (Rhine-Westphalia Institute of Technology Aachen), with optimism. The USA offers more opportunities for molecular imaging. Only recently, new tracers for Alzheimer’s were accepted as reimbursable in some centres, whilst the development of new diagnostics in Europe…
News • Preclinical Alzheimer's disease
Omega-3 supplements and antioxidants may help
New research in The FASEB Journal suggests that clinical trials of omega-3 and antioxidant supplementation should be undertaken for people with Alzheimer's disease with mild clinical impairment.
Novel DNA repair mechanism brings new horizons
A group of researchers, lead by Vasily M. Studitsky, professor at the Lomonosov Moscow State University, discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment and prevention of neurodegenerative diseases. The article describing their discovery is published in AAAS' first open access online-only journal Science Advances.
News • ADAM17
Fight against cancer: Researchers map important enzyme
Danish researchers from the University of Copenhagen have discovered what controls the enzyme that aids the growth of cancer tumours. These findings could be of great value to cancer treatments and has just been published in the renowned journal, Nature Communications.
Fructose produces less rewarding sensations in brain
Fructose not only results in a lower level of satiety, it also stimulates the reward system in the brain to a lesser degree than glucose. This may cause excessive consumption accompanied by effects that are a risk to health, report researchers from the University of Basel in a study published in the scientific journal PLOS ONE. Various diseases have been attributed to industrial fructose in…
News • Gene defects
Cancer brake failure leads to brain cancer
Tumor suppressor genes protect against cancer. Until now, scientists have had to perform complex experiments to detect whether or not a mutation or loss of this gene type does, in fact, cause cancer. Scientists from the German Cancer Research Center (DKFZ) have now used a new gene technology method called CRISPR/Cas9 technology for this detection.
Article • Gentle intervention
Endoscopy jumps the boundaries
‘Health insurers should keep a tighter rein on the quality of endoscopic interventions because, mostly, they represent a gentler alternative to surgery,’ asserts international expert Horst Neuhaus, during an EH interview. Report: Daniela Zimmermann/Juliane Dannert