Article • Biobank
Frozen samples are scientists’ gold
Our knowledge of causes and mechanisms of current and future diseases is on ice – not the perpetual ice of the polar caps but artificial ice. It is stored in biobanks at -80 to -160 °C.
Biomarkers
News • Oncology
Potential new biomarker for cancer patient prognosis
To treat or not to treat? That is the question researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) hope to answer with a new advance that could help doctors and their cancer patients decide if a particular therapy would be worth pursuing.
News • Stroke
Biomarkers May Help Better Predict Who Will Have a Stroke
People with high levels of four biomarkers in the blood may be more likely to develop a stroke than people with low levels of the biomarkers, according to a study published in the August 24, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Sponsored • Screening
What’s new in Cardiac Risk Testing?
It’s well known that cardiovascular disease (CVD) is the leading cause of death in the UK and worldwide. In the UK it is responsible for more than 73,000 deaths annually, affecting 1 in 6 men and 1 in 10 women. With the emergence of such startling statistics, this begs the question, why do routine cholesterol tests still rely on the basic biomarkers high density lipoprotein (HDL), low density…
Article • Transplants
Cell-free DNA offers several advantages
As part of a national, joint research project in cooperation with Chronix Biomedical (San Jose, CA/USA/Göttingen/Germany), Professor Michael Oellerich MD is on new biomarkers in organ transplantation, aiming to develop personalised immunosuppression for patients. This also entails the development of molecular test procedures, among others for the early detection of rejection. The keyword here is…
News • BRIM
Technology helps ID aggressive early breast cancer
When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful? Researchers at the University of Michigan developed a new technology that can identify aggressive forms of ductal carcinoma in situ, or stage 0 breast cancer, from non-aggressive…
Article • Microarrays
Taking biomarker research to a new level
Harnessing the potential of digital pathology is taking research into new and more efficient biomarkers to a new level. By combining strategic planning with the latest digital pathology technology, high quality tissue microarrays for biomarker research are being produced.
News • Biopsy
Tissue biomarker for dementia with lewy bodies and Parkinson's disease
Accurate diagnosis of Parkinson's disease, and the related disease "dementia with Lewy bodies," can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high.
News • amyloid-β
Transmissibility of Alzheimer’s: No clinical symptoms
MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Although the protein associated with Alzheimer’s disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer’s disease. The affected persons…
News • Calibration Verification
Randox Announces New Linearity Sets
Randox Quality Control are pleased to announce, as part of our ongoing growth and development, the launch of our new Acusera Calibration Verification range for Beckman and Roche Cobas instruments.
Article • Wishlist
PACS and imaging biobank assets combined
Personalised medicine relies strongly on biobanking in which medical data are collected on a large scale. Large scale refers both to the amount of data collected per patient as well as to the large number of patients included in the data collection. Although most attention in biobanking has been given to genetic data, proteomics, metabolomics and other –omics technologies, imaging is also being…
Article • EIBALL
Biomarkers increase impact on imaging
‘In imaging there is a trend towards quantification,’ said Professor Siegfried Trattnig, Medical Director of the High-Field MR Centre (HFMRC) at the Medical University Vienna, Austria. Whilst before, radiologists’ findings were subjective, qualitative results, based on signal intensity and grey scale, he pointed out. ‘Today imaging can draw on quantifiable and comparable parameters with…
News • Philips and Banyan Biomarkers
Partnership for handheld blood test to detect and evaluate concussions
Royal Philips and Banyan Biomarkers, Inc. today announced that they have entered into a multi-year joint development agreement to develop and commercialize a new handheld blood test to detect and evaluate mild traumatic brain injury (TBI) - also known as concussion - at the point of care. The new handheld test will be based on Philips’ Minicare I-20 system. The financial details of the…
News • Study
A biomarker for multiple sclerosis
Patients with multiple sclerosis often receive a "hit and miss" treatment when the disease breaks out. A blood analysis is now for the first time able to reveal which of the two most important first-line drugs is better suited for which patients.
Down syndrome research untangles therapeutic possibilities for Alzheimer's
More than five million Americans are living with Alzheimer's disease (AD). Of them, 400,000 also have Down syndrome. Both groups have similar looking brains with higher levels of the protein beta amyloid.
News • Biomarker
Urine test for early stage pancreatic cancer
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, UK researchers have found. The discovery could lead to a non-invasive, inexpensive test to screen people at high risk of developing the disease.
Researchers grow cardiac tissue on “spider silk” substrate
Genetically engineered fibers of the protein spidroin, which is the construction material for spider webs, has proven to be a perfect substrate for cultivating heart tissue cells, MIPT researchers found. They discuss their findings in an article that has recently come out in the journal PLOS ONE.
News • ECCMID 2015
Curetis launches next-generation pneumonia application
Curetis AG, a developer of next-level molecular diagnostic solutions, announced the successful completion of the clinical and analytical CE performance evaluation of its next-generation Unyvero P55 Pneumonia Application. The upgraded cartridge will launch at the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID, April 25 – 28, 2015 in Copenhagen, Denmark) and is…
Interview • Sequencing
Precision medicine in oncology
Professor Hedvig Hricak MD PhD, Chair of the Department of Radiology at the Memorial Sloan-Kettering Cancer Centre, New York, and Professor of Radiology at Cornell University, Ithaca, New York, is a notable expert on crosssectional anatomic and molecular imaging, particularly of gynaecologic and prostate cancers. EH interviewed her about the potential and impact of more precise viewing of inter-…
News • Diabetes
Biomarker for steatohepatitis
40 percent of people in the EU suffer from non-alcoholic steatohepatitis, a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society.
News • ECR 2015
Challenges slow down integration of imaging biomarkers in Europe
Integration of imaging biomarkers in Europe is a challenge, and a number of issues must be overcome so that the full potential of quantitative imaging can be realised, renowned researchers will show in a session today at the ECR.
Validating imaging biomarkers
New imaging biomarkers are helping radiology to play a greater role in new drug developments.
