News • Optional treatment
Radiotherapy: no benefits for older patients with early breast cancer
Radiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.
Metastases
Article • Radioembolization
Breast cancer metastasis: benefits and limitations of trans-arterial therapy
Evidence that radioembolization, a trans-arterial therapy, is safe and stops disease progression in metastatic breast cancer is increasing, a prominent American interventional radiologist showed at the Spectrum conference in Miami.
News • Systems biology
Lung cancer: new discovery could remove metastatic traits
A Korean research team successfully changed the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.
News • Primary tumor or metastasis?
Deep learning and radiomics for precise differentiation in brain tumors
The distinction between primary tumors and metastases can be made quickly and accurately in brain tumors using radiomics and deep learning algorithms, a new study shows.
News • Metastasis research
Some cancer cells can lose their ability to migrate
In a new study, researchers from Kanazawa University show how some intestinal cancer cells lose their ability to spread as they divide and can be eliminated as the cancer grows.
News • Prevalence of metastatic BRCA
New research shows scale of secondary breast cancer in England
A cancer researcher and consultant has estimated for the first time how many women are living with secondary breast cancer in England – in new research which could help to shape cancer services.
News • Metastatic recurrence
Researchers discover mechanism responsible for colon cancer relapse
Researchers in Barcelona discovered the population of residual tumour cells responsible for the recurrence of colorectal cancer in other organs after removal of the primary tumour.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Tumour plasticity
Why breast cancer metastases spread to the bone
A protein vital in determining the organs affected by metastasis has been identified by Swiss researchers. This could lead to the development of therapeutic approaches to suppress metastasis.
News • Histotripsy
Tumors partially destroyed with ultrasound don't come back
Noninvasive sound technology breaks down liver tumors in rats, kills cancer cells and spurs the immune system to prevent further spread.
News • Oncology
Biodegradable hydrogel boosts immune system’s attack on cancers
A new biodegradable gel improves the immune system’s ability to keep cancer at bay after tumors are surgically removed.
News • Metastasis research
How tumour cells ‘camouflage’ to avoid detection in the bloodstream
New insights in the metastasis process: tumour cells pass themselves off as platelets to go undetected in the bloodstream, researchers from Granada have discovered.
News • Cancer proliferation
3D tumour model to unveil metastasis mechanism
Model tumour systems could help explain whether pressure differences can push cancer cells into their surroundings – a basic mechanism behind metastasis.
News • Cancer research
Origins of metastasis unraveled
For a long time, the origin of metastasis remained obscure. Now, scientists have discovered some of the mechanisms these cells arise.
News • Oncology
New blood test identifies if a patient has cancer
Researchers outline a new minimally invasive and inexpensive blood test that can identify cancer in patients with non-specific symptoms and whether these cancers have metastasised in the body.
News • Metastasis research
Study reveals risk of breast cancer spreading to other parts of the body
The risk of early breast cancer spreading to another part of the body ranges from 6% to 22%, according to the first results of a large and detailed global study of metastatic breast cancer presented at the Advanced Breast Cancer Sixth International Consensus Conference (ABC 6). The study also shows that certain women face a higher risk than others, including women diagnosed with breast cancer at…
News • Metastasis research
Tissue-engineered prostate tumours shed light on cancer spread
Research led by the Queensland University of Technology (QUT) on the interaction between prostate cancer cells and the tumour microenvironment has shed more light on the propensity of some types of prostate cancer to metastasize to bone more readily than other types.
News • Treatment guidance
Metastatic prostate cancer comes in two forms
Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment.
News • Promising approach
New nanoparticles suppress resistance to cancer immunotherapy
Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.
News • Combined chemotherapy
Pancreatic cancer: New treatment promising for older patients
Pancreatic cancer is a disease of the elderly: the average age of patients is 72. In Austria, about 1,600 people are diagnosed each year. Since pancreatic cancer has no specific symptoms, it is not usually diagnosed until the tumor is locally advanced or has already metastasized. Once the tumor has metastasized, it is usually no longer treatable by surgery or radiotherapy. In addition, the drug…
News • New cause for tumor spread found
Blood vessels produce growth factor that promotes metastases
Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty Mannheim, Heidelberg University, have identified a new growth factor produced by blood vessels that enables tumor cells to metastatically colonize organs.
News • Stopping the spread
Research sheds new light on pancreatic cancer metastasis
With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death - it is the cancer's ability to evade detection and metastasize to other organs. A team of researchers at the College of Medicine at the University of Oklahoma has published a new study in the journal…
News • Collagen 'pushing'
Supercomputer illustrates mechanical process of cancer growth
According to the World Health Organization, one in six worldwide deaths have been attributed to cancer; however, these fatalities were not due to initial malignant tumors—the deaths were caused by the spread of cancer cells to surrounding tissues and subsequent tumor growth. These tissues, which consist largely of collagen, have been the focus of a recent collaborative study by a team from…
News • Mapping the 'family tree' of cancer
Metastasis monitoring: CRISPR tool catches cancer 'in the act'
When cancer is confined to one spot in the body, doctors can often treat it with surgery or other therapies. Much of the mortality associated with cancer, however, is due to its tendency to metastasize, sending out seeds of itself that may take root throughout the body. The exact moment of metastasis is fleeting, lost in the millions of divisions that take place in a tumor. “These events are…
News • Entering the oncology growth market
Hologic to acquire molecular diagnostics company Biotheranostics
Hologic, Inc. has announced that it will acquire Biotheranostics, Inc., a privately held, commercial-stage company that provides molecular diagnostic tests for breast and metastatic cancers, for approximately $230 million, subject to working capital and other customary closing adjustments.