News • Endoscopic magnetometer
Finding cancer with diamond sensors
Researchers report they have built a new non-toxic and non-radioactive handheld device that uses the unique properties of diamonds to diagnose metastasized breast cancer.
Metastases
News • Respiratory viruses wake up cells in the lungs
How Covid-19 and flu infections revive dormant breast cancer
Common respiratory infections such as influenza and Covid-19 can awaken dormant breast cancer cells that have spread to the lungs, setting the stage for new metastatic tumors, new research finds.
News • Mitochondria-derived nuclear ATP surge
Pressed to the limit: New study explores cancer cell defense mechanism
How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.
News • Fluorescent probe
New visualisation tool targets breast cancer dissemination
In a new study, researchers have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells, to uncover a new therapeutic possibility for limiting breast cancer spread.
News • Machine learning analysis
Breast cancer: AI predicts metastasis from recurrence
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
News • Neuro-Oncology
Why late-stage breast cancer patients should receive routine brain MRI screening
Late-stage breast cancer patients are more often affected by brain metastases than previously believed, a new study finds. The researchers suggest that MRI screening guidelines should reflect this.
News • Machine learning prediction
AI opens non-surgical way to detect brain cancer metastasis
Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery.
News • Driving mechanism identified
Why the lung is a frequent site of cancer metastasis
More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells? New research may have an answer.
News • Tumour movement across tissues
Understanding metastasis: migration strategies of ovarian cancer
A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.
News • Insights into tumor biology
Breast cancer: Exploring metastasis diversity
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
Video • Cancer research
3D-printed tumor model reveals metastasis mechanisms
New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.
News • Promising study results
Cancer of Unknown Primary: on the way to targeted therapies
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
News • Focus on ferroptosis
Major step towards a treatment for metastasis
Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.
News • Circulating tumor extracellular vesicles
Metastatic prostate cancer: better monitoring with new liquid biopsy method
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
News • Research on biomechanics
Tumour 'softness' can drive aggressiveness of breast cancer
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
News • Microbial influence on treatment
Study explores the role of bacteria in cancer
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
News • Omitting axillary lymph node removal
Breast cancer trial explores benefits of less extensive surgery
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
News • Accurate detection and removal
Radioguided surgery to treat metastatic lymph nodes in prostate cancer
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
News • Metastasis susceptibility
How chronic stress spreads cancer
Chronic stress can have a significant impact on health, from an increased risk for heart disease to a greater susceptibility of cancer metastasis. New research points out the underlying mechanisms.
News • Imaging signatures
CT-based radiomics deep learning to predict lymph node metastasis in tumors
With a combination of radiomics and deep learning, researchers aim to noninvasively determine lymph node metastasis before surgery. This could lead to more accurate diagnosis and treatment strategies.
News • Friend and foe in one
Breast cancer: The paradoxical role of white blood cells
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
News • RENACER repository
Brain cancer tissue samples to gain new insights
A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.
News • Breakthrough against metastatic mammacarcinoma
New approach busts chemo resistance of TNBC breast cancer
A team of researchers from Vienna has discovered that dormant breast cancer tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein.
News • New imaging agent
HER2-positive breast cancer: Whole-body PET/CT predicts targeted therapy response
A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.
