Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Research Centre for Environmental Health and the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels – right down to the finest capillaries – including any pathological changes. So…
Scientists of Jena University Hospital, Germany, conducted a meta-analysis to evaluate benefit and risk of paclitaxel-coated balloon angioplasty compared to conventional balloon angioplasty as therapy of intermittent claudication. The study confirms an increased all-cause mortality, which has formerly been stated, and found a broad heterogeneity in the effectivity of the procedure depending on…
Researchers at ETH Zurich have developed a new method for producing malleable microstructures – for instance, vascular stents that are 40 times smaller than previously possible. In the future, such stents could be used to help to widen life-threatening constrictions of the urinary tract in foetuses in the womb. Approximately one in every thousand children develops a urethral stricture,…
Blood clotting is one of the most critical, protective processes in human physiology. When something goes wrong with clotting, either because there is too much clotting, leading to a stroke, or not enough, leading to internal bleeding, the outcome can be catastrophic. Now, University at Buffalo researchers have established an in vitro model of this process that will help clinicians improve…
Researchers in the Medical Sciences Division of Oxford University have established a key cause of micro blood vessels constricting during surgery to reopen a blocked artery, and identified a potential therapeutic target to block the mechanism behind it. During the emergency procedure used to reopen the blocked artery causing a heart attack, smaller "micro" blood vessels can remain…
Researchers have discovered that a family of lipids (fats) contribute to the development of a serious aortic disease, by driving clotting in the blood vessel wall. The findings could lead to the development of new treatments for this potentially life threatening condition. The team, led by researchers at Cardiff University, in collaboration with colleagues at Oxford and Erlangen, discovered that…
In a groundbreaking new study led by University of Minnesota biomedical engineers, artificial blood vessels bioengineered in the lab and implanted in young lambs are capable of growth within the recipient. If confirmed in humans, these new vessel grafts would prevent the need for repeated surgeries in some children with congenital heart defects.
EPIC Alliance experts at the European Society of Cardiology (ESC) congress presented original research and real-world clinical evidence on non-responders to cardiac resynchronization therapy (CRT) and atrial fibrillation (AF) ablation.
In addition the technique to grow the blood vessels in a 3D scaffold cuts down on the risk of transplant rejection because it uses cells from the patient. It was developed by researchers from the University of Bath's Department of Pharmacy and Pharmacology, working with colleagues at Bristol Heart Institute.
For the examination of coronary blood vessels, intravascular methods with imaging technologies are already state-of-the-art. However, ultrasonic methods, which are used to gather information about the tissue, can only be used externally, up to now. The piezo electronical components necessary for this have not been sufficiently miniaturized to be inserted into the blood vessels.
A drug currently being trialled in cancer patients could also be used to treat an often incurable condition that can cause painful blood vessel overgrowths inside the skin, finds new research in mice led by UCL, Memorial Sloan Kettering (MSK) Cancer Center in New York and the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona.
A research team headed by scientists at the Institute of Neuroimmunology and the Institute for Multiple Sclerosis Research (IMSF), University Medical Center Göttingen (UMG), has gained new insights into the immune function of cerebrospinal fluid (CSF). They used real-time microscopy to film the lively trafficking of immune cells between the CSF and the nervous tissue. Here the meninges play the…
A common heart drug may stop the progression of angiosarcoma, a cancer of the inner lining of blood vessels, according to a study by researchers at Texas Tech University Health Sciences Center (TTUHSC) El Paso.
A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists.
With the world’s elderly population expected to double by 2050, understanding how aging affects the body is an important focus for researchers globally. Cardiovascular disease, the No. 1 cause of death worldwide, often is associated with aging arteries that restrict blood flow. Now, University of Missouri researchers have identified an age-related cause of arterial dysfunction, a finding that…
Researchers have identified a new test that can be used to predict the likelihood of a patient developing heart failure, or even dying following a heart attack.
A blood clot is a dangerous health situation with the potential to trigger heart attacks, strokes and other medical emergencies. To treat a blood clot, doctors need to find its exact location. But current clinical techniques can only look at one part of the body at a time, slowing treatment and increasing the risk for complications. Now, researchers are reporting a method, tested in rats, that…
Blood clots often form when lipid-rich plaques on the inner surface of arteries rupture and platelets aggregate at the site of injury. LMU cardiologists have now compared the effects of two new platelet aggregation inhibitors.
Results from six international randomised controlled studies conclusively and uniformly confirm, for the very first time, the effectiveness of thrombectomy in patients with acute, severe ischaemic strokes caused by a blood clot in one of the proximal cerebral arteries. The endovascular procedure is an add-on to conventional thrombolysis. EH reports from a German Stroke Society (DSG) press…
Research published in the Proceedings of the National Academy of Sciences (PNAS) demonstrates that technology invented by researchers at Oregon Health & Science University’s Casey Eye Institute can improve the clinical management of the leading causes of blindness. Optical coherence tomography (OCT) angiography could largely replace current dye-based angiography in the management of these…
Blocked blood vessels can quickly become dangerous. It is often necessary to replace a blood vessel – either by another vessel taken from the body or even by artificial vascular prostheses. Together, Vienna University of Technology and Vienna Medical University have developed artificial blood vessels made from a special elastomer material, which has excellent mechanical properties. Over time,…
Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty in Mannheim at Heidelberg University are searching for new approaches to prevent liver fibrosis. They have identified a surface molecule on special liver cells called stellate cells as a potential target for interfering with this process. When the researchers turned off the receptor, this led to reduced liver…
Neurologists keenly debate the value of mechanical reopening of blocked blood vessels in the brain, as demonstrated during the 21st World Congress for Neurology (WCN) in Vienna this September. Theoretically, endovascular thrombolysis can only be considered for 20-30% of all incidents of stroke.
Study described in The New England Journal of Medicine is the first to show cause-and-effect relationship between a gene variant and calcium deposits on the aortic valve.