Microscopy

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News • Microscopy

New Olympus BX53 microscope with True Color LED

Olympus’ new BX53 microscope provides bright, sharp images with excellent color rendering performance equivalent to halogen lamps. The long-life LED light source, the True Color LED, is brighter and more uniform than a 100-watt halogen bulb – matching every contrast method and providing bright images to multi-head discussion systems for up to 26 people.

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News • Time-lapse microscopy

Image correction software simplifies quantification of stem cells

Today, tracking the development of individual cells and spotting the associated factors under the microscope is nothing unusual. However, impairments like shadows or changes in the background complicate the interpretation of data. Now, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have developed a software that corrects images to make hitherto hidden…

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Article • Light microscopy

An image is worth a thousand words

Light microscopy today offers a wealth of techniques that provide fascinating insights into life on subcellular level. “In light microscopy these days there are so many new techniques that each of us can only handle a subset of them,” says Christian Tischer, scientific officer in der Advanced Light Microscopy Facility of the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…

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News • Microscopy

Watching molecular machines at work

When one cell divides into two - that is how all forms of life are propagated - the newly born daughter cells have to be equipped with everything they will need in their tiny lives. Most important of all is that they inherit a complete copy of the genetic information from their mother cell. If this is not the case because a wrong number of chromosomes – on which the genetic information is…

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Article • Research

First accurate simulation of a virus invading a cell

For the first time, scientists know what happens to a virus’ shape when it invades a host cell, thanks to an experiment by researchers at Penn State College of Medicine and University of Pittsburgh School of Medicine. Understanding how the virus shape specifically changes could lead to more effective anti-viral therapies.

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News • Microscopy

New Patents for Lightsheet Readout Mode in CMOS Cameras

Hamamatsu Photonics has been granted patents for their “Lightsheet Readout Mode” which takes advantage of the rolling shutter readout in scientific CMOS cameras. Lightsheet Readout Mode is currently available in the ORCA-Flash4.0V2 camera. The patents place Hamamatsu’s cameras in an ideal position regarding the lightsheet application and Hamamatsu will move forward on enforcing their rights…

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News • Neurosurgery

Microscope imaging system integrates virtual reality technology

Joshua Bederson, MD, Professor and System Chair for the Department of Neurosurgery at Mount Sinai Health System, is the first neurosurgeon to use CaptiView – a microscope image injection system from Leica Microsystems that overlays critical virtual reality imaging directly onto the brain when viewed through the eyepiece, known as the ocular, during surgery.

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News • BRIM

Technology helps ID aggressive early breast cancer

When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful? Researchers at the University of Michigan developed a new technology that can identify aggressive forms of ductal carcinoma in situ, or stage 0 breast cancer, from non-aggressive…

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Article • Digitisation

Pathology departs from a dark back room

A UK-based neuropathologist has highlighted how the digitisation of pathology will play a pivotal role in taking patient care on to a new and more efficient level. Speaking in a recent Webinar under the heading The Adoption and Benefits of Digital Pathology for Primary Diagnosis, Dr Daniel du Plessis also noted how the digital era would raise the profile of pathology and ‘bring it out of the…

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News • MOZART

Imaging cells and tissues under the skin

Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal.

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News • Surfing DNA

Enzyme catches a ride to fight infection

Scientists have shown for the first time that an enzyme crucial to keeping our immune system healthy “surfs” along the strands of DNA inside our cells. The researchers used extremely powerful microscopy to watch how the enzyme AID (activation-induced deoxycytidine deaminase) moves around and interacts with other molecules.

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News • State-of-the-art

First pictures of cells' DNA-copying machinery

The first-ever images of the protein complex that unwinds, splits, and copies double-stranded DNA reveal something rather different from the standard textbook view. The electron microscope images, created by scientists at the U.S. Department of Energy's Brookhaven National Laboratory with partners from Stony Brook University and Rockefeller University, offer new insight into how this molecular…

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