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Article • Evaluation

Calculated therapy is the objective

At a recent focus meeting held in Berlin by the Association of Accredited Laboratories in Medicine, Dr Andreas Weimann, managing director at the Laboratory Berlin – Charité Vivantes Services, spoke of the challenges that laboratories working with hospitals face due to the management of pathogens and the diagnosis of infections.

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Interview • Viruses

Measles, mumps, rubella threaten youngsters

Before his presentation at ECCMID 2016, Dr Guillaume Béraud, Infectious Disease Specialist, in the Centre Hospitalier Universitaire de Poitiers, Poitiers, France, talked to European Hospital about the results from his modelling of these three “childhood” diseases measles, mumps and rubella.

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News • Lung cancer

“Liquid biopsy” blood test detects genetic mutations

A simple blood test can rapidly and accurately detect mutations in two key genes in non-small cell lung tumors, researchers at Dana-Farber Cancer Institute and other institutions report in a new study – demonstrating the test’s potential as a clinical tool for identifying patients who can benefit from drugs targeting those mutations.

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News • Small cell lung cancer

Clues to the cause of chemoresistance discovered

Small cell lung cancer is not usually detected until it is at an advanced stage, when metastases have already formed. Chemotherapy is very effective initially but, within a year, cancer recurs and this time does not respond to a course of chemotherapy. The research group headed by Gerhard Hamilton, University Department of Surgery at MedUni Vienna, has now managed to identify the reason for this…

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News • Rio de Janiero

First description of 2015 Zika virus outbreak

Since the recent link to severe neurological defects in infants born to mothers infected during pregnancy, Zika virus (ZIKV) has become a public health and research priority. A study reports details from the 2015 Zika outbreak in Rio de Janeiro - the first with a high proportion of cases confirmed by molecular diagnosis - and proposes changes to the current diagnostic criteria for ZIKV disease.

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New PTH Control for Randox QC Portfolio

Randox Quality Control is pleased to announce a further expansion to their comprehensive QC portfolio, the Acusera PTH Control. This new control has been designed with convenience in mind, providing your laboratory with a true third party solution for the measurement of PTH. Our assayed liquid control has been developed with an extended open vial stability of 30 days and 2 year shelf life,…

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News • Inflammatory bowel disease

International consensus report highlights need for improved management of CDI

Results from an international consensus project involving a multidisciplinary group of clinicians have been presented today at 26th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2016. A current lack of data on outcomes in patients with IBD who have CDI means that appropriate choice of treatment strategy can be unclear. The consensus examines the issues impacting…

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News • Neurology

Zika virus may now be tied to another brain disease

The Zika virus may be associated with an autoimmune disorder that attacks the brain's myelin similar to multiple sclerosis, according to a small study that is being released today and will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

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News • Nanoscale devices

Revealing the fluctuations of flexible DNA in 3-D

An international team working at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) has captured the first high-resolution 3-D images from individual double-helix DNA segments attached at either end to gold nanoparticles. The images detail the flexible structure of the DNA segments, which appear as nanoscale jump ropes.

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News • bacterial enzyme

Possible approach to tackle infections from hospital germs

Microbiologists at the Universities of Münster and Nottingham, in England, have analysed an enzyme which might play an important role in the treatment of infections from the hospital germ pseudomonas aeruginosa. They have decoded the three-dimensional structure of the enzyme and revealed its function.

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News • MOZART

Imaging cells and tissues under the skin

Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal.

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News • Rapid testing

West Africa, Ebola and the threat of Zika

Rapid testing for the Zika virus is a critical need in the recent Ebola-affected countries of Liberia, Sierra Leone and Guinea, says a Georgetown University professor, because of the recent Zika outbreak on nearby Cape Verde and the similarity in symptoms between Zika and early Ebola.

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News • Prevention

Next step in preventing diabetes

A team of scientists at Helmholtz Zentrum München, in collaboration with Technische Universität München and the German Center for Diabetes Research (DZD), have shown in a preclinical model that specifically modified insulin mimetopes may lead to an immune tolerance. The results, published in ‘Nature Communications’, may be a step to improved prevention of type 1 diabetes.

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News • Infectiology

Immune factor allows viral infections to become chronic

Many viral diseases tend to become chronic – including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently. Scientists at the University of Bonn have now identified an immune factor which is partially responsible for this. Their results give rise to hopes for new therapeutic approaches. The work, which included researchers…

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News • Drug delivery vehicles

Stealth effect of nanocarriers conferred more efficiently

By using drug delivery vehicles, so-called nanocarriers, pharmaceuticals reach the diseased area in the body. There they accelerate the healing process. But in order to prevent them from getting ingested by phagocytes, the surfaces of the nanocarriers are typically coated with the biocompatible synthetic polymer poly(ethylene glycol) (PEG). Scientists at the Mainz University Medical Center and…

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News • Oncology

Pancreatic cancer: Enzyme renders tumors resistant

Scientists at the German Cancer Research Center (DKFZ) and the Stem Cell Institute HI-STEM in Heidelberg have discovered the reason why some pancreatic tumors are so resistant to treatment. They have found that these tumor cells produce larger quantities of an enzyme that usually occurs in the liver and degrades many drugs. If this enzyme is blocked, the cancer cells become sensitive towards…

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