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Interview • Infection control

Virologists are today’s universal necessities

Globalisation has been a defining term in this 21st century: with almost anybody able to visit any place at any time, diseases, viruses and bacteria can be travel companions. Thus virology is gaining increased attention. Professor Barbara Gärtner, President of the German Association of Virology, talks about the issues and challenges arising from this development.

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News • Breast Cancer

Biomarker Identified for Likely Aggressive, Early Stage Breast Cancer

The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk ‘in situ’ lesions, an estimated 85% of which would never progress to invasive cancers. Meanwhile, the standard conservative treatment is insufficient for many early-stage tumors that have progressed past the in situ…

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News • Kidney Transplants

White Blood Cells Control Virus Replication

Certain white blood cells play an important role in bringing a harmful virus under control after kidney transplantations. The results of a research group at the Department of Biomedicine at the University of Basel and University Hospital Basel could contribute to improving control of immunosuppression, avoiding transplant rejection and developing relevant vaccines.

News • Investigating deaths

Wide variability in coroner decision-making

Coroners in England and Wales don’t seem able to agree on what caused a person’s death or whether the death merits an inquest or not - despite being faced with identical case information - reveals a small study published online in the Journal of Clinical Pathology.

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Article • Immunoassay

CLIA: Advancement and market dynamic

With the combination of the basic principle of radioimmunoassay, high sensitive chemiluminescence and high specific immunoassay, the year 1977 saw the emergence of a new technology-Chemiluminescence Immunoassay (CLIA) which provided one of the best solutions for the quantification of specimens from a complex mixture with the non-radioactive nature, making it an advantage to replace RIA in…

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News • Psychological consequences

Cortisol excess hits natural DNA process hard

High concentrations of the stress hormone, Cortisol, in the body affect important DNA processes and increase the risk of long-term psychological consequences. These relationships are evident in a study from the Sahlgrenska Academy on patients with Cushing’s Syndrome, but the findings also open the door for new treatment strategies for other stress-related conditions such as anxiety, depression…

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News • Blood flow control

"Switch" in brain’s capillary network monitors activity

All it takes is the flip of a protein “switch” within the tiny wire-like capillaries of the brain to increase the blood flow that ensures optimal brain function. New research has uncovered that capillaries have the capacity to both sense brain activity and generate an electrical vasodilatory signal to evoke blood flow and direct nutrients to nourish hard-working neurons.

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News • Heart Attacks

Potential Breakthrough in Determining Who’s at Risk

Researchers are revisiting their views on the relative dangers soft and hard atherosclerotic plaque deposits pose to heart health. Findings of a new study by researchers at the Intermountain Medical Center Heart Institute may be a “game-changer” for determining who’s at risk of a heart attack, they say.

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News • DNA

DNA labels predict mortality

Methyl labels in the DNA regulate the activity of our genes and, thus, have a great influence on health and disease. Scientists from the German Cancer Research Center and from the Saarland cancer registry have now revealed that an altered methylation status at only ten specific sites in the genome can indicate that mortality is increased by up to seven times. Smoking has a particularly…

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News • Autism

Big Data techniques find biomarkers for Autism Spectrum Disorder (ASD)

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study. The algorithm, developed by researchers at Rensselaer Polytechnic Institute, is the first physiological test for autism and opens the door to earlier diagnosis and potential future development of therapeutics.

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Article • Deep Learning

Philips and LabPON plan to create world’s largest pathology database

Royal Philips (NYSE: PHG, AEX: PHIA) and LabPON, the first clinical laboratory to transition to 100% histopathology digital diagnosis, today announced its plans to create a digital database of massive aggregated sets of annotated pathology images and big data utilizing Philips IntelliSite Pathology Solution1. The database will provide pathologists with a wealth of clinical information for the…

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Article • Spanish expert separates fables from facts

Seasonal over-indulgence

In the early months of a New Year many of us are tightening our belts after Christmas gastronomic indulgences. However, the belt may not be as long as it used to be and the gym treadmill may be the only answer.

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Article • Emergency Imaging

Forensics identify victims and terrorists

‘I am sorry, the electricity will be cut off because we’re going to simulate an attack, or emergency exercise, this morning,’ explained Dr Wim Develter, when he suddenly delayed his interview with Mélisande Rouger of European Hospital. They were about to discuss computed tomography, and its role not only in advanced healthcare and other more unexpected areas, such as the arts and…

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News • Lab Study

A protein called PERK - Treating progressive supranuclear palsy

The brain disease “progressive supranuclear palsy” (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech. Scientists at the German Center for Neurodegenerative Diseases (DZNE) and the Technical University of Munich (TUM) have now discovered a molecular mechanism that may help in the search…

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