UK – A partly refurbished building in central Oxford is opening to provide space for science entrepreneurs. Science Oxford, a charity that supports education and business in the city, ultimately aims to demolish the building to create a science-focused public building to showcase new technological innovation from the Oxford area.
The closure of Pfizer’s Sandwich Lab is part of a long-term decline in drug development, a trend that has been affecting all major UK pharmaceutical multinationals. Big pharmaceutical companies have been downsizing, outsourcing and merging in an attempts to find an innovation strategy that will keep their pipelines filled with new, potentially profitable products.
There will be nearly 1.3 million deaths from cancer in Europe in 2011 according to predictions from a study published in the cancer journal, Annals of Oncology. The estimates, which have been reached after researchers used for the first time in Europe a new mathematical model for predicting cancer mortality, show a fall in overall cancer death rates for both men and women when compared to 2007.
Who has not dreamed at least once to live in future times? Who would not want that one’s today incurable diseases may be cured in the future by medical progress? Long-time cryopreservation immediately after death is the betting ticket to that future.
Cold plasma jets could be a safe, effective alternative to antibiotics to treat multi-drug resistant infections, says a study published this week in the January issue of the Journal of Medical Microbiology. The team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but…
Chemical substances can bring miracles: they kill bacteria, prevent viral multiplication or stop cancer cell growth. Thus they offer a huge reservoir of potential drugs. However, seeking substances and their biological effects is a mammoth task and cannot be undertaken alone. The Preparatory Phase Project EU-OPENSCREEN (European Infrastructure of Open Screening Platforms for Chemical Biology) was…
Yes, cancer research is making rapid progress, but -- how can the transfer of cancer research into successful treatments be accelerated? In Berlin this October, that vexing question was up for discussion during the European Forum on Oncology. Also on the agenda: How best practice approaches to cancer therapy can be adopted throughout the European Union.
Across Europe an estimated 3.2 million new cases and 1.7 million deaths occur annually. By intensified cooperation in research, diagnosis and treatment, enormous advantages can be achieved. To progress the integration of knowledge and skills in this field, the first European Forum on Oncology was held this October in Berlin.
Researchers from Italy determined that radiofrequency ablation (RFA) is a safe and effective therapy for managing hepatocellular carcinoma (HCC) in cirrhotic patients. The high repeatability of RFA is advantageous in controlling recurrences of cancerous tumors in the liver. Results of this 10-year retrospective study are available in the January 2011 issue of Hepatology, a journal published by…
The exact location of Santa’s Workshop has long been kept secret, but one thing every child knows is that he lives somewhere up by the North Pole. It’s a place that has seen great changes in recent years with melting sea ice and warmer summer temperatures attributed to global warming.But climate change isn’t the only bad news facing the world’s favorite jolly old elf: research from the…
Norwegian studies indicate that people with osteoporosis have a greater risk of developing cardiovascular disease, and vice versa. Now researchers believe they have found a biological system that may influence both disease processes.
Interfaces between the brain and electrical circuits in technical devices or computers open new perspectives for basic research and medical application, e.g., for therapeutic brain stimulation and neuroprosthetics. The new EU project CORONET will develop the technological and theoretical foundations for such future “bio-hybrid” interfaces between biological and artificial nervous tissues.
Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published today in the scientific journal Nature Communications. Their discovery shows that the body’s immune system can cause more illnesses than realised.
At RSNA 2010, Sectra launched the Sectra Visualization Table. This unique solution for collaborative work improves decision making efficiency in acute care, allowing physicians to efficiently set the care strategy in multi-trauma cases. It also serves as a platform for medical education, clinical conferences and virtual autopsies.
Clues to the causes of serious, and often fatal, diseases and conditions, such as heart disease, stroke and high blood pressure, are being investigated at the Universities of Strathclyde and Glasgow, both in Scotland, with the use of a £1 million grant.
Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, German neuroscientists have now discovered that neurons systematically recycle the protein components necessary for transmitter…
Numerous studies have shown that cocoa has a protective effect against cardiovascular diseases. The reason for this has now been uncovered by researchers at Linköping University in Sweden. When a group of volunteers devoured a good-sized piece of dark chocolate, it inhibited an enzyme in their bodies that is known to raise blood pressure.
It sounds like an idea plucked from the realms of science fiction writing. But in this case, there is nothing fictional about it. Scientists in Yorkshire have developed a process that uses the luminous cells from jellyfish to diagnose cancers deep within the human body.
Cancer stem cells (CSCs) are the engine that drives tumour growth. They can not only reproduce themselves but also differentiate to form all the specialised cells found within a tumour. While chemotherapy and radiotherapy non-specifically target all rapidly dividing cells, there is increasing evidence that CSCs are more resistant to these treatments. Report: Karoline Laarmann
Researchers at Karolinska Institutet have shown that they may be able to monitor the aging process in the brain, by using MRI technique to measure the brain lactic acid levels. Their findings suggest that the lactate levels increase in advance of other aging symptoms, and therefore could be used as an indicator of aging and age-related diseases of the CNS.
Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. In the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic…
Advancing magnetic resonance imaging (MRI) up the Tesla scale may sound good, but will it produce the results and patient safety radiologists actually desire? Faced with the question: ‘How many Tesla should it be?’, Professor Siegfried Trattnig MD, head of the Centre of Excellence in high-field MRI at the University Clinic for Radiodiagnostics, Medical University of Vienna, and Austria’s…
Even more precise diagnoses, even better process controls -- the future of MR-PET technology has dawned. The first commercial, full-body hybrid scanners are either waiting in the wings or already installed. But what does the introduction of the MR-PET really mean for clinical practice? Professor Heinz-Peter Schlemmer MD, Head of the Radiology Department at the German Cancer Research Centre in…
Detection of circulating and disseminated tumour cells in blood is a promising method to diagnose cancer dissemination, or to follow up cancer patients during therapy. Today’s methods and involve time-consuming (more than a day) sample processing and cell isolation steps -- all labour intensive and expensive. A lab-on-chip that could integrate those processing steps would enable faster,…
Small and with a life cycle of just two weeks, fruit flies are seen by many as pests and a problem all year round. However, for nearly a century, the humble insect, officially known as Drosophila melanogaster, which measures no more than 3mm, has performed a vital role in genetics and developmental biology. Fruit flies are genetically diverse and easy to use in research, helping scientists in a…