Interview • Tumour triggers
Can cancer be contagious?
No self-respecting TV crime series is without a pathologist – but the fictitious pathologist who incessantly solves crimes has little to do with reality.
Bacteria
News • Breakthrough
Gut bacteria drive growth of stem cells in colon cancer
Colon cancer is one of the most common forms of cancer in Germany. Prof. Dr. med. Sebastian Zeißig, group leader at the DFG Research Center for Regenerative Therapies Dresden (CRTD) - Cluster of Excellence at the TU Dresden and physician at the Department of Medicine I, University Hospital Carl Gustav Carus Dresden, has now shown a decisive role of gut bacteria in the regulation of intestinal…
News • E. coli
Using harmless bacteria to fight cancer
Several bacterial species have pledged promise in fighting tumors. However, most of them are pathogens. In order to use them as a weapon against cancer and other diseases in humans, researchers must find a balance between their therapeutic aggressiveness and safety for the patient. To overcome this problem, researchers at the Helmholtz Centre for Infection Research (HZI) have shifted their focus…
News • Bacteria
3D images of megaenzymes may improve antibiotics
Taking clear pictures of megaenzymes isn’t easy. But it’s definitely worth it. These proteins play an active role in creating many common antibiotics. They are in constant motion, with sections that flip around acrobatically to carry out necessary tasks. Now, for the first time, McGill researchers have been able to take a series of 3D images of a large section from one of these…
News • E. coli
Identify most dangerous strains of often-deadly bacteria
A multi-disciplinary group of researchers at the University of Maryland School of Medicine (UM SOM) have for the first time determined the genetic makeup of various strains of E. coli, which every year kills hundreds of thousands of people around the world.
News • Respiratory infection
Under the weather? A blood test can tell if antibiotics are needed
Researchers at Duke Health are fine-tuning a test that can determine whether a respiratory illness is caused by infection from a virus or bacteria so that antibiotics can be more precisely prescribed.
News • Oncology
Scientists use dead bacteria to kill colorectal cancer
Led by Professor Teoh Swee Hin, scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.
Article • Infection
Trial pitches MGB-BP-3 against clostridium difficile
Scientists at the University of Strathclyde in Glasgow have been working to identify compounds with important anti-infective activity and suitable for treating serious infectious diseases caused by bacteria and parasites, such as Clostridium difficile. Their work has led to the creation of the new drug known as MGB-BP-3 (MGB = minor groove binder). Report: Mark Nicholls
News • WHO
Public misunderstanding about antibiotic resistance
As the World Health Organization (WHO) ramps up its fight against antibiotic resistance, a new multi-country survey shows people are confused about this major threat to public health and do not understand how to prevent it from growing.
News • Linac Coherent Light Source
A glimpse into live bacteria
A group of scientists in Sweden has taken an important step towards the goal of peering inside a working cell. They are among researchers around the globe who are seeking a method that enables the observation of proteins, lipids and DNA inside individual cells, as well as gaining a better understanding of how this intricate and interconnected system changes with time.
Article • Politics
Spain’s response to EU directive
Increasingly resistant bacteria are a global problem and require innovative action from all parties concerned, says Jesús Rodriguez-Baño, President of the Scientific Committee of the annual meeting of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), which unfolded last May in Seville. EH asked him why the creation of a national plan has become necessary to tackle…
News • bacterial communities
What’s lurking in your lungs?
With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs – the community of microscopic organisms that are…
News • Molecular Genetics
How a Bacterial Cell Recognizes its Own DNA
It may come as a bit of a surprise to learn that bacteria have an immune system – in their case to fight off invasive viruses called phages. And like any immune system – from single-celled to human – the first challenge of the bacterial immune system is to detect the difference between “foreign” and “self.” This is far from simple, as viruses, bacteria and all other living things…
Article • Infectious diseases
Carrying home a nosocomial infection
About 6-8% of Spanish patients will develop an infection during or after a hospital stay. Can these infections be avoided? How is Spain facing up to the challenge? Dr Juan Pablo Horcajada, Head of the Department of Infectious Diseases at Hospital del Mar, Barcelona, and spokesperson of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), assessed the situation and…
News • Microscope technique
Speeding identification of deadly bacteria
A new way of rapidly identifying bacteria, which requires a slight modification to a simple microscope, may change the way doctors approach treatment for patients who develop potentially deadly infections and may also help the food industry screen against contamination with harmful pathogens, according to researchers at the Korea Advanced Institute of Science and Technology (KAIST) in Daejeon,…
Microbes on the International Space Station
Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places.
New chip makes testing for antibiotic-resistant bacteria faster
Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time.
Article • Fast, accurate and convenient
New test identifies early sepsis
A newly launched test enables the quantitative determination of PCT in serum samples, EDTA or lithium heparin plasma samples by latex enhanced immunoturbidimetric methodology. The Stanbio Chemistry Procalcitonin (PCT) LiquiColor Assay was launched by EKF Diagnostics, based in Cardiff, Wales, which explains: ‘Procalcitonin is a marker for bacterial infection and sepsis and has been recognised as…
News • Clostridium difficile
Evidence supports success of fecal transplants in treatment
Research published in the open access journal Microbiome offers new evidence for the success of fecal microbial transplantation (FMT) in treating severe Clostridium difficile infection (CDI), a growing problem worldwide that leads to thousands of fatalities every year.
News • Plastic plus egg whites
Recipe for antibacterial plastic
Bioplastics made from protein sources such as albumin and whey have shown significant antibacterial properties, findings that could eventually lead to their use in plastics used in medical applications such as wound healing dressings, sutures, catheter tubes and drug delivery, according to a recent study.
News • Antibiotics
Antibiotic use by travelers may add to global spread of superbugs
Taking antibiotics for diarrhea may put travelers visiting developing parts of the world at higher risk for contracting superbugs and spreading these daunting drug-resistant bacteria to their home countries, according to a new study published in Clinical Infectious Diseases and now available online.
New antibiotic shows promise in treating drug-resistant bacteria
Scientists have discovered a new antibiotic, teixobactin, that can kill serious infections in mice without encountering any detectable resistance, offering a potential new way to get ahead of dangerous evolving superbugs.
Article • Study
Jet air and warm air driers unsuitable for use in healthcare settings
A new study concludes that jet air and warm air hand driers have a greater potential to contaminate washrooms by spreading bacteria into the air and onto users and bystanders. The findings have significant implications for infection control health professionals and purchasing managers responsible for equipping hospital washrooms.
Now available: ESBL-Tool kit for handling beta-lactamase resistant Enterobacteriaceae
Doctor Véronique Mondain from Nice explains the ambitious project she and colleagues have put in place to help combat the rise of these resistant pathogens.
Peering into the abyss
In May, the World Health Organisation (WHO) warned that bacterial infections might lead to an increasing number of deaths because new resistance mechanisms threaten our ability to treat common infectious diseases.