Scientists at the University of Strathclyde in Glasgow have been working to identify compounds with important anti-infective activity and suitable for treating serious infectious diseases caused by bacteria and parasites, such as Clostridium difficile. Their work has led to the creation of the new drug known as MGB-BP-3 (MGB = minor groove binder). Report: Mark Nicholls
As the World Health Organization (WHO) ramps up its fight against antibiotic resistance, a new multi-country survey shows people are confused about this major threat to public health and do not understand how to prevent it from growing.
A group of scientists in Sweden has taken an important step towards the goal of peering inside a working cell. They are among researchers around the globe who are seeking a method that enables the observation of proteins, lipids and DNA inside individual cells, as well as gaining a better understanding of how this intricate and interconnected system changes with time.
Increasingly resistant bacteria are a global problem and require innovative action from all parties concerned, says Jesús Rodriguez-Baño, President of the Scientific Committee of the annual meeting of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), which unfolded last May in Seville. EH asked him why the creation of a national plan has become necessary to tackle…
With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs – the community of microscopic organisms that are…
It may come as a bit of a surprise to learn that bacteria have an immune system – in their case to fight off invasive viruses called phages. And like any immune system – from single-celled to human – the first challenge of the bacterial immune system is to detect the difference between “foreign” and “self.” This is far from simple, as viruses, bacteria and all other living things…
About 6-8% of Spanish patients will develop an infection during or after a hospital stay. Can these infections be avoided? How is Spain facing up to the challenge? Dr Juan Pablo Horcajada, Head of the Department of Infectious Diseases at Hospital del Mar, Barcelona, and spokesperson of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), assessed the situation and…
A new way of rapidly identifying bacteria, which requires a slight modification to a simple microscope, may change the way doctors approach treatment for patients who develop potentially deadly infections and may also help the food industry screen against contamination with harmful pathogens, according to researchers at the Korea Advanced Institute of Science and Technology (KAIST) in Daejeon,…
Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places.
Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time.
A newly launched test enables the quantitative determination of PCT in serum samples, EDTA or lithium heparin plasma samples by latex enhanced immunoturbidimetric methodology. The Stanbio Chemistry Procalcitonin (PCT) LiquiColor Assay was launched by EKF Diagnostics, based in Cardiff, Wales, which explains: ‘Procalcitonin is a marker for bacterial infection and sepsis and has been recognised as…
Research published in the open access journal Microbiome offers new evidence for the success of fecal microbial transplantation (FMT) in treating severe Clostridium difficile infection (CDI), a growing problem worldwide that leads to thousands of fatalities every year.
Bioplastics made from protein sources such as albumin and whey have shown significant antibacterial properties, findings that could eventually lead to their use in plastics used in medical applications such as wound healing dressings, sutures, catheter tubes and drug delivery, according to a recent study.
Taking antibiotics for diarrhea may put travelers visiting developing parts of the world at higher risk for contracting superbugs and spreading these daunting drug-resistant bacteria to their home countries, according to a new study published in Clinical Infectious Diseases and now available online.
Scientists have discovered a new antibiotic, teixobactin, that can kill serious infections in mice without encountering any detectable resistance, offering a potential new way to get ahead of dangerous evolving superbugs.
A new study concludes that jet air and warm air hand driers have a greater potential to contaminate washrooms by spreading bacteria into the air and onto users and bystanders. The findings have significant implications for infection control health professionals and purchasing managers responsible for equipping hospital washrooms.
An ‘Achilles heel’ in the defensive barrier surrounding drug-resistant bacterial cells has been identified by a team of scientists at the University of East Anglia (UEA) in Norwich, UK.
In May, the World Health Organisation (WHO) warned that bacterial infections might lead to an increasing number of deaths because new resistance mechanisms threaten our ability to treat common infectious diseases.
Doctor Véronique Mondain from Nice explains the ambitious project she and colleagues have put in place to help combat the rise of these resistant pathogens.
‘Better hygiene’ is the frequently and loudly recommended panacea in the intensifying struggle against hospital-acquired infections (HAIs). However there are currently no evidence-based studies that evaluate the efficacy of additional hygiene measures.
The world’s first gene cancer therapy study of an innovative oral vaccine is underway at the Surgical Clinic of Heidelberg University Hospital.
Five recommendations to prevent central venous catheter-related infections. Catheter-related bloodstream infections are the third frequent infection in the intensive care unit (ICU) after pneumonia and peritonitis worldwide. The incidence of CVC infections lies between 1-4 for 1,000 catheterdays. This means for the USA, as an example, that more than five million patients annually need a central…
The smaller the child, the more defenceless it is against viral and bacterial attacks. That is why infection accompanied by the symptom of a high temperature is the most common illness in children. So, when a child has a runny nose and fever an infection is clear. The more elemental question is: Should it be treated with antibiotics?
Antimicrobial resistance (AMR) is becoming more prevalent around the world, constituting a serious threat to public health. When bacteria acquire resistance against antibiotics, common medical procedures – for example, in surgery – become impossible due to the high infection risk. Keep reading to find out about AMR research, development of new antibiotics and antibiotic alternatives.
