Professor Marco Catani suggests the best explanation for Leonardo da Vinci's inability to finish his works is that the great artist may have had Attention Deficit and Hyperactivity Disorder. Leonardo da Vinci produced some of the world’s most iconic art, but historical accounts of his work practices and behaviour show that he struggled to complete projects. Drawing on these accounts, Professor…
Virtual reality (VR) can identify early Alzheimer’s disease more accurately than ‘gold standard’ cognitive tests currently in use, suggests new research from the University of Cambridge. The study highlights the potential of new technologies to help diagnose and monitor conditions such as Alzheimer’s disease, which affects more than 525,000 people in the UK. In 2014, Professor John…
Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a study published in Biological Psychiatry. A UC San Diego School of Medicine team of scientists, headed by senior author Davide Dulcis, PhD, associate professor in the…
A novel imaging technique that uses a synthesized form of scorpion venom to light up brain tumors has shown promise in a clinical trial. The imaging system enables neurosurgeons to better see malignant growths that often are difficult to fully eliminate.
A new vaccination for malignant astrocytoma brings such patients hope. However, research is still in its infancy. We spoke with Professor Michael Platten, Medical Director of the Neurological Clinic at Medical University Mannheim, about the present state of research and the serious opportunities this presents. During the interview, he also revealed how cooperation with the pharmaceutical industry…
A recently recognized brain disorder that mimics clinical features of Alzheimer’s disease has for the first time been defined with recommended diagnostic criteria and other guidelines for advancing and catalyzing future research. Scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly-named pathway to dementia,…
Cognitive impairment associated with cancer, also known as “chemobrain”, has gained recognition as a complication of the disease and its treatment, as it can negatively affect the daily lives of cancer patients and survivors. Chemobrain can be subtle yet persistent, with some cancer patients reporting difficulties related to memory and attention even months after completing their treatment.…
Behavioural problems in young people with severe antisocial behaviour – known as conduct disorder – could be caused by differences in the brain’s wiring that link the brain’s emotional centres together, according to new research led by the University of Birmingham. Conduct disorder affects around 1 in 20 children and teenagers and is one of the most common reasons for referral to child…
The speed of the human brain is remarkable. Almost immediately upon being exposed to stimuli, neurons are activated, prompting subconscious reactions and, a fraction of a second later, thought. But the speed at which we can noninvasively follow brain function using an MRI is not as impressive. Functional MRI (fMRI), which measures changes in blood-oxygen levels, has revolutionized neuroscience by…
A protein complex has been shown to play a key role in preventing the build-up of toxic plaques in the brain linked to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease. An international team of researchers from the Universities of Leeds, Stanford (USA) and Konstanz (Germany) have discovered that the nascent polypeptide-associated complex (NAC) helps to prevent the…
A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease (CMT). The findings point to a pathway to possible treatments for this disease and better understanding of other neurodegenerative disorders, including Alzheimer's disease, that affect millions. The study focused on two related proteins, MFN2 and…
Inside the body, disease and injury can leave behind quite the mess — a scattering of cellular debris, like bits of broken glass, rubber and steel left behind in a car accident. Inside the central nervous system (CNS), a region that includes the brain and spinal cord, it is the job of certain cells, called microglia, to clean up that cellular debris. Microglia have counterparts called…
The debilitating behaviours and all-consuming thoughts which affect people with severe obsessive compulsive disorder (OCD), could be significantly improved with targeted deep brain stimulation, according to the findings of a new study. OCD is characterised by unwanted intrusive thoughts (obsessions) and repetitive stereotyped behaviours (compulsions- sometimes called rituals) and often means…
Where are we coming from? Where are we going? Where are we right now? Our sense of spatial orientation gives us answers to these questions. We spoke with Professor Thomas Wolbers about the problems of diagnosing orientation disturbances and how the measurement of our sense of space could help in the fight against neuro-degenerative illnesses such as Alzheimer’s.
Researchers at the University of North Carolina School of Medicine used MRI brain scans and machine learning techniques at birth to predict cognitive development at age 2 years with 95 percent accuracy. “This prediction could help identify children at risk for poor cognitive development shortly after birth with high accuracy,” said senior author John H. Gilmore, MD, Thad and Alice Eure…
With a weak alternating electrical current sent through electrodes attached to the scalp, UNC School of Medicine researchers successfully targeted a naturally occurring electrical pattern in a specific part of the brain and markedly improved depression symptoms in about 70 percent of participants in a clinical study.
Research in the past several years has shown that children can outgrow a diagnosis of autism spectrum disorder (ASD), once considered a lifelong condition. In a new study, researchers at Albert Einstein College of Medicine and Montefiore Health System have found that the vast majority of such children still have difficulties that require therapeutic and educational support.
A minimally invasive procedure to determine whether patients with drug-resistant epilepsy are candidates for brain surgery is safer, more efficient, and leads to better outcomes than the traditional method, according to new research by The University of Texas Health Science Center at Houston (UTHealth).
Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego, with colleagues around the country, report that inhibiting activity of a specific protein in glioblastomas (GBM) boosts their sensitivity to radiation, thus improving treatment prospects for one of the most common and aggressive forms of brain cancer. The findings are published…
White matter on the brain is a difficult subject. Even the terminology is varied, making differential diagnosis complex. An understanding of prevalence and of the tools available to facilitate the diagnosis of individual diseases is important, Dr Gunther Fesl, radiologist at Praxis Radiologie Augsburg, explains.
Ultra-high-field magnetic resonance tomography with field strength of 7 Tesla is slowly but surely entering clinical routine. ‘Thanks to very high spatial and spectral resolution, ultra-high-field MR permits detailed views of the human anatomy and can show precisely the metabolic processes such as those in the brain,’ said Professor Siegfried Trattnig, from Vienna’s Medical University.
Cancer researchers at the University of Bonn have reported significant progress in the treatment of glioblastoma. About one third of all patients suffer from a particular variant of this most common and aggressive brain tumor. Survival of these patients treated with the new combination therapy increased on average by nearly half compared to patients who received the standard therapy.
‘Night owls’ – those who go to bed and get up later – have fundamental differences in their brain function compared to ‘morning larks’ , which mean they could be disadvantaged by the constraints of a normal working day.
Until now, neurologists were largely convinced that having a higher level of education would build some kind of protective barrier against neurodegenerative diseases like Alzheimer's. But a new study finds that education does not play a role in when the disease starts or how fast it progresses. The study was published in the online issue of Neurology, the medical journal of the American Academy…
Neuroscientists at Emory University School of Medicine have discovered a focal pathway in the brain that when electrically stimulated causes immediate laughter, followed by a sense of calm and happiness, even during awake brain surgery. The effects of stimulation were observed in an epilepsy patient undergoing diagnostic monitoring for seizure diagnosis. These effects were then harnessed to help…