Neuroscientists at Emory University School of Medicine have discovered a focal pathway in the brain that when electrically stimulated causes immediate laughter, followed by a sense of calm and happiness, even during awake brain surgery. The effects of stimulation were observed in an epilepsy patient undergoing diagnostic monitoring for seizure diagnosis. These effects were then harnessed to help…
Poor sleep has long been linked with Alzheimer’s disease, but researchers have understood little about how sleep disruptions drive the disease. Now, studying mice and people, researchers at Washington University School of Medicine in St. Louis have found that sleep deprivation increases levels of the key Alzheimer’s protein tau. And, in follow-up studies in the mice, the research team has…
Alzheimer's disease is often marked by a creeping progression: Years before symptoms of Alzheimer’s disease manifest, the brain starts changing and neurons are slowly degraded. Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Hertie Institute for Clinical Brain Research (HIH) and the University Hospital Tübingen now show that a protein found in the blood can be used…
Brain imaging in patients with cognitive complaints need to be viewed differently when using MRI to diagnose and treat patients with dementia, says Dr. Christopher Hess, who will discuss the role of MRI in the adjunctive diagnosis of dementia in his talk at the Garmisch Symposium. In addition, general radiologists need to recognize the important findings related to dementia when making a…
In his talk at the Garmisch Symposium, entitled “MRI in 5 minutes – Dream or Reality?” Dr. Daniel Sodickson of the New York University School of Medicine will give attendees a preview of the MR scanners of the future, which he likens to self-driving cars. Sodickson — a professor and vice chair for research in the department of radiology at NYU, a principal investigator at the Center…
Using a common type of brain scan, researchers programmed a machine learning algorithm to diagnose early-stage Alzheimer's disease about six years before a clinical diagnosis is made – potentially giving doctors a chance to intervene with treatment.
A new neurostimulator developed by engineers at the University of California, Berkeley, can listen to and stimulate electric current in the brain at the same time, potentially delivering fine-tuned treatments to patients with diseases like epilepsy and Parkinson's. The device, named the WAND, works like a "pacemaker for the brain," monitoring the brain's electrical activity and…
The prospect of an actively personalized approach to the treatment of glioblastoma has moved a step closer with the recent publication in Nature of favorable data from the phase 1 study GAPVAC-101, testing a novel therapeutic concept tailored to specific characteristics of patients’ individual tumors and immune systems. For the first time, the feasibility of such a highly personalized form of…
As mammals age, their sense of smell deteriorates. In a study published in the journal ‘Cell Reports’, an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case. For their study, the researchers tracked the development of stem cells in the brains of mice using what are known as confetti reporters. They then…
Patients who undergo heart surgery do not experience major memory changes—either better or worse—when compared with those who have a much less invasive, catheter-based procedure, according to a study published online in The Annals of Thoracic Surgery. “It was comforting to see that the differences in cognitive decline between the two heart procedures are small, even though one involves…
When infants are playing with objects, their early attempts to pay attention to things are accompanied by bursts of high-frequency activity in their brain. But what happens when parents play together with them? New research, published in the open-access journal PLOS Biology, by Dr Sam Wass of the University of East London in collaboration with Dr Victoria Leong (Cambridge University and Nanyang…
Obstetricians and midwives often warn new mothers about postpartum depression. They might mention what symptoms women should look out for—such as crying spells or extreme irritability—and where they can turn for help. But people who have strokes may not learn that they, too, are at risk for depression. Post-stroke depression stems from the cardiovascular changes in the brain that lead to a…
Siemens Healthineers and Insightec announce the CE clearance of Exablate Neuro compatible with Magnetom Skyra, Prisma and Prisma Fit scanners from Siemens Healthineers. Exablate Neuro uses focused ultrasound for treatments deep within the brain with no surgical incisions. MR imaging provides a complete anatomical survey of the treatment area, patient-specific planning and real-time outcome…
Traumatic experiences can become deeply entrenched in a person's memory. How can fears following a traumatic event be reduced in the long term and prevented from becoming a permanent stress-related disorder? Researchers at the Mainz University Medical Center have recently shed new light on these questions. The key to their approach lies in firmly anchoring new, positive experiences in the…
Researchers at Johns Hopkins Medicine have identified in live human brains new radioactive “tracer” molecules that bind to and “light up” tau tangles, a protein associated with a number of neurodegenerative diseases including Alzheimer’s disease and other related dementias.
New data reveals the life expectancy of patients with kidney cancer that’s traveled to the brain has now stretched from months to years. UT Southwestern Kidney Cancer Program investigators report survival rates beyond 2.5 years for some patients with specialized multidisciplinary care. Historically, patients whose kidney cancer had spread to the brain were believed to have only about six months…
A collaborative study led by a neurologist at Rush University Medical Center and an environmental scientist at the University of Illinois at Chicago suggests that weather patterns that cause dramatic changes in barometric pressure may increase the incidence of a type of stroke known as spontaneous intracerebral hemorrhage, that is, the rupture of a blood vessel in the brain. The researchers…
This could be a major step towards a better understanding of the functions of deeply hidden brain compartments, such as the formation of memories, as well as related dysfunctions, including Alzheimer’s disease. Researchers from the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena and the University of Edinburgh have succeeded in using a hair-thin fibre endoscope to gain insights…
One day, MRI brain scans may help predict whether older people will develop dementia, new research suggests. In a small study, MRI brain scans predicted with 89 percent accuracy who would go on to develop dementia within three years, according to research at Washington University School of Medicine in St. Louis and the University of California San Francisco. The findings, presented at the…
A world where machines can be controlled by thought alone – such is the promise of so-called brain-computer interfaces (BCI). BCIs are both hardware and software communication systems that read brain and nerve signals, convert those into electrical signals and translate human thoughts into machine commands. Developers of BCIs rely on artificial intelligence, neural network models and big data…
Virtual Reality (VR) technology is aiding trainee surgeons to practise complex procedures in a simulated setting, rather than learning skills on real patients. VR is also helping to demystify neurosurgery in that it enables medical students and patients to ‘enter’ and experience a neurosurgical operating theatre. Alex Alamri, a trainee neurosurgeon at Barts Health NHS Trust in London, UK,…
Imec, the world-leading research and innovation hub in nanoelectronics and digital technologies, released and is making available its state-of-the-art high-density neural probe, Neuropixels, to the global neuroscience research community. With almost a thousand electrodes, and 384 recording channels on a single shank, the Neuropixels probe provides an unprecedented resolution for mapping brain…
Chronic stress is a well-known risk factor for the development of psychiatric illnesses including depression disorders. The brain requires a great deal of glucose, and stress is known to alter glucose metabolism. However, if stress-associated mental impairments are linked to affected glucose metabolism remains to be seen. Researchers at the Department for Psychiatry and Psychotherapy at the Mainz…
A research team led by the University of Alabama at Birmingham is launching a study to find a better model for glioblastoma, a particularly devastating type of brain tumour, to help determine the most appropriate treatment modality. The $3.6 million, five-year U01 grant award is funded by the National Cancer Institute, one of the National Institutes of Health. The UAB team will join four other…
The first successful surgery under anaesthesia occurred in the 1840s. Since then, people have been developing theories about what might be going on in the brain while a person is unconscious. Even after thousands of surgeries, researchers still don’t understand exactly which specific areas of the brain are responsible for transitioning into unconsciousness and back.