In early 1990, at Analytica, in Munich, a young US-American researcher Kary B Mullis received the award for biochemical analytics for his 1983 invention: the polymerase chain reaction (PCR) – a success topped in 1993 by the Nobel Prize for chemistry. Mullis’ work revolutionised DNA copying, a process which, before PCR, had taken weeks. Whilst initially PCR was used to create digital…
Recent research in Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has identified two enzymes that can detect Covid-19 RNA as simply as a pregnancy test Jesús Pla, an eminent microbiologist at the Complutense University in Madrid, explained in our exclusive interview. CRISPR technology could help alleviate workloads in packed hospitals and expand testing to primary care and…
Scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours - read more in the MEDICA magazine.
Large proportions of patients can be safely triaged either to rule out discharge or rule in lifesaving management – if following the European Society of Cardiology (ESC) Guidelines Class I recommendation of two serial measurements of hs-cTnI on admission and after one hour, if there are assay specific cut off values for the 0/1 algorithms. The Pathfast hs-cTNI assay is an approved system to…
Beckman Coulter announced the launch of its Access SARS-CoV-2 Immunoglobulin M (IgM) assay in countries accepting the CE Mark. The new IgM antibody test demonstrated 99.9% specificity with 1,400 negative samples and 100% sensitivity at >18 days post symptom onset and post positive PCR. Beckman Coulter’s IgM assay is part of a full suite of testing solutions the company is developing to…
The accuracy of a rapid finger-prick antibody test for SARS-CoV-2, the virus responsible for covid-19 infection, may be considerably lower than previously suggested, finds a study published by The BMJ. The results suggest that if 10% of people given the test had previously been infected, around 1 in 5 positive test results would be incorrect (false positive results). These conclusions contrast…
As the leading supplier for tube identification and sorting devices, ASP Lab Automation AG designed the new generation of their tube sorter ASP SortPro for a throughput of 3.600 tubes per hour.
The academic teaching Karlsruhe Hospital, at the University of Freiburg, is the largest hospital providing tertiary care in the Middle Upper Rhine Valley. Every year, 63,000 in-patients and 180,000 out-patients are treated in the 1,500-bed facility with 50 departments and 30 out-patient clinics. Inevitably, a hospital of this size has a central lab. We spoke with Dr Horst Mayer, managing senior…
In order to analyze tumors, they have to be cut into thin slices. Now, a new technology has been developed that makes pieces of the tumor visible in 3D without cutting them.
Injuries due to contaminated puncture devices are still the most frequent cause of accidents in hospitals. This is a significant source of danger for many employees in the healthcare industry. At this moment in time, there are already more than 20 bloodborne pathogens that we know of. The most dangerous are HBV, HCV and HIV. Recent studies show that it is up to ten times more likely for more…
Merck announced a collaboration with Mammoth Biosciences Inc. for the development, scale-up and commercial production of Mammoth’s CRISPR-based SARS CoV-2 diagnostic test.
This year, the MEDICA LABMED FORUM will offer a high-profile programme with top speakers which is free for registered online visitors.
Research and innovation hub Imec announced that it has started developing a groundbreaking SARS-CoV-2 test. Unlike current approaches (using blood, saliva, or a nasopharyngeal swab), the new test will identify SARS-CoV-2 virus particles in a person’s exhaled breath. The solution promises the accurate identification of a contagious case in less than five minutes.
Mass spectrometry-based metabolomics has emerged as a powerful tool to help study chemical ecology. Recent advances in the technique make it possible to study microbial interactions from complex communities. Laia Castaño-Espriu outlined the role and benefits of MS in this context in her presentation ‘Analysis of microbial ecology by mass spectrometry-based metabolomics techniques’, at the…
In 2019, the Central Laboratory of the Institute for Clinical Chemistry and Pathobiochemistry at the Klinikum rechts der Isar of the Technical University Munich, headed by Professor Peter B Luppa, organised the 4th of the internationally renowned Munich Point-of-Care Testing Symposiums. Dr Andreas Bietenbeck is senior physician at the Institute which for many years has been focusing on…
The fight against bacterial infections, especially those caused by resistant pathogens, is in full swing with the search for new antibiotic agents. The aim is to identify substances that attack the pathogens in a truly novel way. The team at the Center for Systems-Based Antibiotic Research (Cesar) at Ruhr-Universität Bochum (RUB) has described in two publications how assess if a new antibiotic…
In an emergency, point-of-care-testing can provide results in minutes. However, sources of error must be understood to ensure result accuracy and confident diagnosis (particularly important during the current pandemic). Medical teams frequently use POCT devices to assess acutely ill patients; a hospital’s diagnostic laboratory is responsible for the analysers, plus training non-laboratory…
A method for detecting traumatic brain injury at the point of care has been developed by scientists at the University of Birmingham. Using chemical biomarkers released by the brain immediately after a head injury occurs, researchers are able to pinpoint when patients need urgent medical attention. This saves time in delivering vital treatment and avoids patients undergoing unnecessary tests where…
It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans. Even decades of research have only produced a few standardized vaccines and strategies for treatment to combat just a small number of viruses. Nor…
A team at Purdue University has developed a novel testing platform to evaluate how breast cancer cells respond to the recurrent stretching that occurs in the lungs during breathing. The technology is designed to better understand the effects that the local tissue has on metastatic breast cancer to study how metastases grow in a new tissue.
Xyall BV, a medtech innovator in molecular pathology, has entered into a multi-year, strategic partnership with Motic, a world leader in microscopy and digital pathology systems. Their goal is to develop an automated, high-precision table-top tumour tissue dissection solution for hospital-based molecular pathology laboratories.
As COVID-19 infections begin to rise again, a novel testing strategy proposed by researchers at the University of Oxford at the start of the pandemic has become urgent once again. The strategy aims to bring the virus’s reproduction number (‘R’) down to below 1, by concentrating testing resources on particular groups in the population that are most likely to spread the infection to others,…
A unique, ground-breaking global campaign, which has seen major pharmaceutical companies unite to fight antibiotic resistant infections, has been launched with a one-billion-dollar investment fund. The Antimicrobial Resistance (AMR) Action Fund aims to help save the collapsing antibiotic pipeline and make 2-4 new antibiotics available within a decade.
Surface disinfection has proved an effective method to control Covid-19 infection, as virologists from the Ruhr University Bochum (RUB) have shown. However, an effective disinfection strategy against Coronavirus must consider various factors, says Professor Eike Steinmann, head of the Department of Molecular and Medical Virology at the RUB.
From glass slides to the realm of ones and zeros: Digitising pathology offers many benefits to the specialty. Read our information channel for some of the most exciting applications.