Probing the mystery of how cancer cells die
You’ve probably never heard of “sphingolipids” before. But these curiously named organic compounds play a vital role in one of humanity’s most well-known diseases: cancer.
Research
Gene variation promotes uncontrolled cell division
Mom’s eyes and dad’s tumor? Cancer is due to genetic defects, some of which can be hereditary. The gene variant rs351855, for example, occurs in one in two cancer patients. A team headed by Axel Ullrich from the Max Planck Institute of Biochemistry in Martinsried identified the gene variant a decade ago. Now, they succeeded for the first time in showing that the variation exposes an otherwise…
News • σ=p*r/2h
Physics Law Applied to Improve Left-Sided Heart Failure
Cardiologists from 15 centers in 6 countries have evaluated a new approach for the treatment of Left-Sided Heart Failure under the leadership of Stefan D. Anker, MD, Ph.D., Professor of Innovative Clinical Trials at the Cardiology and Pulmonology Clinic in the Heart Center of the Medical University Göttingen (UMG). The investigators in the clinical evaluation entitled AUGMENT-HF demonstrated…
News • Silicon
Research center combine electronics and photonics in neural probes
At the IEEE International Electron Devices Meeting 2015, world-leading nanoelectronics research center imec, KU Leuven, and Neuro-Electronics Research Flanders (NERF, set up by VIB/KU Leuven and imec) presented a set of silicon neural probes that combine 12 monolithically integrated optrodes using a CMOS compatible process.
News • Epigenetic marks
Sperm carries information about dad's weight
Turns out dads are also eating for two. A study published in Cell Metabolism reveals that a man's weight affects the heritable information contained in sperm. The sperm cells of lean and obese men possess different epigenetic marks, notable at gene regions associated with the control of appetite. The comparisons, which included 13 lean men and 10 obese men, offer one biological explanation for…
When rejection comes from within
A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre (CRCHUM.)
Nanotech weapon against chronic bacterial infections in hospitals
Australian researchers develop a new technique that tricks bacterial biofilms into dislodging from their protective matrix, making them vulnerable to treatment with antibiotics.
First serotonin neurons made from human stem cells
Su-Chun Zhang, a pioneer in developing neurons from stem cells at the University of Wisconsin-Madison, has created a specialized nerve cell that makes serotonin, a signaling chemical with a broad role in the brain.
Treating colon cancer with vitamin A
A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. There are many reasons for this, but one has to do with a group of persisting cancer cells in the colon that cause relapses. Conventional therapies against them are mostly ineffective. EPFL scientists have now identified a biological mechanism that can be exploited to counteract colon cancer relapses.
News • There's an app for that
An easy, fast and reliable way to record causes of death
Researchers from the University of Melbourne have developed a revolutionary new app to capture accurate global cause of death data on tablets and mobile phones.
Cause of organ dysfunction in Down syndrome
While most Down syndrome research has focused on the brain, a new report by Johns Hopkins University biologists uncovers how the disorder hampers a separate part of the nervous system that plays a key role in health and longevity.
Helicopter parenting at doctor's office may impact teen health
Majority of parents take control at routine visits, but may impede teens' health care independence researchers from the University of Michigan Health System say.
News • Cancer trial
Suicide gene therapy kills prostate tumor cells
Results from a long-term clinical trial conducted by cancer researchers at Houston Methodist Hospital show that combining radiation treatment with "suicide gene therapy," a technique in which prostate cancer cells are genetically modified so they signal a patient's immune system to attack them, provides a safe and effective one-two punch against the disease.
Diagnostics with birefringence
Nothing could be simpler: a drop of blood is placed on a special carrier substance; after a wait of a few minutes, the slide is placed on a device that emits polarised light thanks to an inexpensive polarisation filter. It is covered with a lid containing a second polarisation filter, which blocks the light from all materials except crystalline or materials with directional properties.
News • Research
Why do children develop cancer?
As new scientific discoveries deepen our understanding of how cancer develops in children, doctors and other healthcare providers face challenges in better using that knowledge to guide treatment and counsel families and patients. In addition, as more children continue to survive pediatric cancer, that counseling may extend into a patient’s adulthood and old age.
News • Biogel
Intelligent gel attacks cancer
A new injectable “biogel” is effective in delivering anti-cancer agents directly into cancerous tumours and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre (CRCHUM), has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.
News • “Jumping Gene” Mystery
Grabbing a parasite by the tail
Deep within your DNA, a tiny parasite lurks, waiting to pounce from its perch and land in the middle of an unsuspecting healthy gene. If it succeeds, it can make you sick. Like a jungle cat, this parasite sports a long tail. But until now, little was known about what role that tail plays in this dangerous jumping. Now, scientists report that without a tail, this parasitic gene can’t jump…
Lower patient satisfaction in hospitals that employ more nurses trained abroad
Many Western countries including England and the United States have come to rely on nurses trained abroad in times of nurse shortages. Yet little is known about how such practices affect quality of care and patient satisfaction.
Patient mood can impact medical procedure results
Feeling high levels of distress, fear and hostility prior to undergoing an angioplasty or other interventional radiology procedure may lead to a poor outcome, according to new research presented at the annual meeting of the Radiological Society of North America (RSNA).
New funding for Ebola hides an ongoing decline
A new report gives the first ever picture of global investment in Ebola research and development (R&D), reporting that this investment might have come at the expense of efforts to develop drugs, vaccines and diagnostics for other neglected diseases, which collectively cause more than six million deaths every year in developing countries.
Terahertz detection and emission
UPM participates in the ZOTERAC project, whose technology could replace the conventional X-ray sources in medicine or improve the detection of weapons and explosives.
News • RSNA 2015
Breast MRI after mammography may identify additional aggressive cancers
Additional breast cancers found with MRI are sometimes larger and potentially more aggressive than those found on mammography, according to a study published online in the journal Radiology.
Testosterone replacement makes Type 2 diabetic men more sensitive to insulin
Findings demonstrate that testosterone is a metabolic hormone as well as a sex hormone, University at Buffalo researchers say.
Article • Infection
Trial pitches MGB-BP-3 against clostridium difficile
Scientists at the University of Strathclyde in Glasgow have been working to identify compounds with important anti-infective activity and suitable for treating serious infectious diseases caused by bacteria and parasites, such as Clostridium difficile. Their work has led to the creation of the new drug known as MGB-BP-3 (MGB = minor groove binder). Report: Mark Nicholls
SyMRI to be studied as a technology to characterize brain tumors
SyntheticMR and The University of Texas MD Anderson Cancer Center have signed a research agreement to study SyMRI to characterize brain tumors.
