News • Developing Nations
Researchers turn bubble wrap into tiny test tubes
Inexpensive packing material pops up as an alternative to high-cost glass lab equipment for simple diagnostic tests, a potential boon in developing nations.
Laboratory
Article • POCT
Evolutionary POCT
A growing number of clinical tests are being delivered in community hospitals with more patients receiving quicker, accurate diagnoses closer to home, without stays in acute hospital beds. Professor Daniel Lasserson, an Associate Professor in the Nuffield Department of Primary Care Health Sciences at Oxford University, shares the opinion that using point-of-caretesting (POCT) to facilitate high…
Sponsored • Digital Pathology
Take the next step in Digital Pathology
Digitizing pathology is not just a transformation of technology, the major change and benefits lies in the change to a more efficient workflow – enabled by the new technology.
Sponsored • Bad blood
Haemolysis must be avoided
Blood sampling via intravenous catheters frequently occurs because patients in intensive care already have intravenous catheters in place, and patients admitted to accident and emergency units are immediately set up with intravenous catheters – providing easy access to blood.
Article • Infection control
From alcohol to cancer detection
Clinical trials are under way at two NHS hospitals in England to assess breathalyser technology to detect lung cancer. Phase I clinical trials of a diagnostic breathalyser developed by Cambridge-based Owlstone Ltd have shown accurate identification of 12 lung cancer biomarkers in breath specimens. A Phase II trial is now targeting development of a small, handheld device that can be used in GP…
Article • Diabetes II
Manufacturers declare support
This year’s German medical diagnostics manufacturers association (Verband der deutschen Diagnostica-Hersteller = VDGH) congress, focused on diabetes. The panel discussion that closed the evening session revealed unanimous support for the adoption of a German national diabetes plan. Report: Bettina Döbereiner
Interview • Mass Spectrometry
Connected components are not enough
Bringing liquid chromatography and tandem mass spectrometry (LC-MS/MS) testing into clinical laboratories has been a slow process but continues to show promise to help improve patient care. The medical device industry is on the edge of fundamental breakthroughs that can help drive the adoption into more mainstream clinical laboratories. We recently sat down with Dr Bori Shushan, Mass Spectrometry…
Article • Research
Genetic alterations
This article discusses examples of applications of genetic analyses in coagulation disorders and haematological and oncological diseases. Professor Christine Mannhalter highlights the impact changes have on the occurrence and severity of diseases and their influence on therapy response. Report: Christine Mannhalter
Placenta-on-a-chip
National Institutes of Health (NIH) researchers and their colleagues have developed a "placenta-on-a-chip" to study the inner workings of the human placenta and its role in pregnancy.
Article • MALDI-TOF
Identifying a single isolate in minutes
When trialled in Swansea, Wales, Matrix Assisted Laser Desorption Ionisation – Time of Flight (MALDI-TOF) demonstrated sufficient advantages over conventional methods to be introduced into routine practice.
Article • Antimicrobial stewardship
A diagnostic marker reduces antibiotics use
Since 2009, as part of diagnostic and antimicrobial stewardship strategies, Hampshire Hospitals National Health Service (NHS) Trust has used serum procalcitonin (PCT) – an innovative and highly specific marker to diagnose clinically relevant bacterial infections and sepsis. Report: Mark Nicholls
Article • Politics I
Austria’s notable national action plan
Surveillance, hygiene and infection prevention, antimicrobial stewardship, diagnosis of infectious diseases, use of antimicrobial medicines as well as reporting and information. Report: Michael Krassnitzer
Article • Politics
The S4 laboratory
Health always has a political dimension, as seen at two recent international events - the World Health Summit in Geneva in May and the G7 Summit in the Bavarian Alps near Garmisch at the beginning of June. Report: Anja Behringer
Agendia co-Founder wins European Inventor Award for breast bancer test
Agendia co-founder and Chief Research Officer, Laura van't Veer, Ph.D., has won the European Inventor Award in the SME category. The European Inventor Award is a prestigious innovation award presented by the European Patent Office, with only 15 inventors nominated in a total of five categories worldwide.
Medical school: Call for sustainable biomedical research funding
Unstable funding is threatening the viability of academic biomedical research, according to a new paper published this week in the journal Science Translational Medicine. The paper was written jointly by the deans of 19 prominent medical schools around the USA. Among this group is University of Maryland School of Medicine Dean E. Albert Reece.
A chip placed under the skin for more precise medicine
Several EPFL laboratories are working on devices allowing constant analysis over as long a period as possible. The latest development is the biosensor chip, created by researchers in the Integrated Systems Laboratory working together with the Radio Frequency Integrated Circuit Group. Sandro Carrara is unveiling it today at the International Symposium on Circuits and Systems (ISCAS) in Lisbon.
On-demand X-rays at synchrotron light sources
Scientists who use synchrotron light sources are welcoming an era of "on-demand" X-rays, in which they have access to the light beams they want thanks to a technique developed at the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab).
New chip makes testing for antibiotic-resistant bacteria faster
Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time.
Article • Research
A recipe for long-lasting livers
People waiting for organ transplants may soon have higher hopes of getting the help that they need in time. Researchers at the RIKEN Center for Developmental Biology have developed a new technique that extends the time that donor organs last and can also resuscitate organs obtained after cardiac arrest.
Article • Mutations
Dutch scientists build colon cancer progression model
Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.
Article • Nosocomial infections
Hygiene begins between the ears
"Infection prevention and control is a matter of awareness and continuous education," says Dr Ernst Tabori, Medical Director of the German Consulting Centre for Hospital Epidemiology and Infection Control (BZH), at the University Hospital Freiburg, specialises in building hygiene in hospitals and outpatient healthcare facilities, as well as surgical units. Report: Anja Behringer
Sponsored • POCT
This market will boom
The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…
Article • Cancer diagnostics I
Ambiguity calls for a second opinion
Each year, approximately 1.6 million women in the USA have breast biopsies to diagnose or rule out cancer. Pathological diagnosis is considered the gold standard – how accurate are these diagnoses? Report: Cynthia E. Keen
Article • Excellence Award
ESCMID honours Médecins Sans Frontières
The European Society of Clinical Microbiology and Infectious Disease (ESCMID) today issued a special excellence award for outstanding achievement to Médecins Sans Frontières (MSF). The award was bestowed in Copenhagen at ESCMID’s annual congress, on behalf of all its members, in light of the charity’s huge contribution to global health over the last 40-years, and in special recognition of…
Article • Human resources
A pathology workforce fit for the future
The UK pathology sector faces numerous challenges as it strives to create a future medical laboratory workforce. As in many divisions of the National Health Service (NHS), this area has an ageing population yet must evolve against a backdrop of fast-developing technologies, emerging science, financial constraints and the challenge of working in tandem with the private sector. Report: Mark…