Laboratory

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Article • POCT

Evolutionary POCT

A growing number of clinical tests are being delivered in community hospitals with more patients receiving quicker, accurate diagnoses closer to home, without stays in acute hospital beds. Professor Daniel Lasserson, an Associate Professor in the Nuffield Department of Primary Care Health Sciences at Oxford University, shares the opinion that using point-of-caretesting (POCT) to facilitate high…

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Article • Infection control

From alcohol to cancer detection

Clinical trials are under way at two NHS hospitals in England to assess breathalyser technology to detect lung cancer. Phase I clinical trials of a diagnostic breathalyser developed by Cambridge-based Owlstone Ltd have shown accurate identification of 12 lung cancer biomarkers in breath specimens. A Phase II trial is now targeting development of a small, handheld device that can be used in GP…

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Article • Research

Genetic alterations

This article discusses examples of applications of genetic analyses in coagulation disorders and haematological and oncological diseases. Professor Christine Mannhalter highlights the impact changes have on the occurrence and severity of diseases and their influence on therapy response. Report: Christine Mannhalter

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Interview • Mass Spectrometry

Connected components are not enough

Bringing liquid chromatography and tandem mass spectrometry (LC-MS/MS) testing into clinical laboratories has been a slow process but continues to show promise to help improve patient care. The medical device industry is on the edge of fundamental breakthroughs that can help drive the adoption into more mainstream clinical laboratories. We recently sat down with Dr Bori Shushan, Mass Spectrometry…

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Article • Antimicrobial stewardship

A diagnostic marker reduces antibiotics use

Since 2009, as part of diagnostic and antimicrobial stewardship strategies, Hampshire Hospitals National Health Service (NHS) Trust has used serum procalcitonin (PCT) – an innovative and highly specific marker to diagnose clinically relevant bacterial infections and sepsis. Report: Mark Nicholls

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A chip placed under the skin for more precise medicine

Several EPFL laboratories are working on devices allowing constant analysis over as long a period as possible. The latest development is the biosensor chip, created by researchers in the Integrated Systems Laboratory working together with the Radio Frequency Integrated Circuit Group. Sandro Carrara is unveiling it today at the International Symposium on Circuits and Systems (ISCAS) in Lisbon.

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Article • Mutations

Dutch scientists build colon cancer progression model

Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.

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Article • Nosocomial infections

Hygiene begins between the ears

"Infection prevention and control is a matter of awareness and continuous education," says Dr Ernst Tabori, Medical Director of the German Consulting Centre for Hospital Epidemiology and Infection Control (BZH), at the University Hospital Freiburg, specialises in building hygiene in hospitals and outpatient healthcare facilities, as well as surgical units. Report: Anja Behringer

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Article • Human resources

A pathology workforce fit for the future

The UK pathology sector faces numerous challenges as it strives to create a future medical laboratory workforce. As in many divisions of the National Health Service (NHS), this area has an ageing population yet must evolve against a backdrop of fast-developing technologies, emerging science, financial constraints and the challenge of working in tandem with the private sector. Report: Mark…

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Article • Excellence Award

ESCMID honours Médecins Sans Frontières

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) today issued a special excellence award for outstanding achievement to Médecins Sans Frontières (MSF). The award was bestowed in Copenhagen at ESCMID’s annual congress, on behalf of all its members, in light of the charity’s huge contribution to global health over the last 40-years, and in special recognition of…

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Sponsored • POCT

This market will boom

The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…

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Sponsored • QUALITY CONTROL

Made to measure laboratories

In 1995 Claudia and Robert Karl risked self-employment in a sector already dominated by experts. Those manufacturers, however, sold standardised products. The Karls, with backing from a stainless steel producer, decided to produce tailor-made solutions to fit customers’ needs. To that end they attended international medical equipment exhibitions from Dubai through to Malaysia. Today, Claudia…

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