News • ATLL therapy approach
New gene targets for treating adult blood cancer
Scientists from Hokkaido University have identified new targets for treating Adult T-cell leukemia/lymphoma (ATLL), an aggressive form of blood cancer with existing drugs.
Hematology
Sponsored • Hematology equipment
Taking morphology analysis to the next level
Mindray has launched the new MC-80 Automated Digital Cell Morphology Analyzer, a revolutionary cell morphology system that provides more clarity, more intelligence and more productivity for morphological analysis. Combining MC-80, Mindray’s hematology solution will revolutionize the high-end hematology segment.
News • Relapse research
Multiple myeloma: Tracking down resistant cancer cells
In multiple myeloma, a cancer of the bone marrow, relapse almost always occurs after treatment. Initially, most patients respond well to therapy. However, as the disease progresses, resistant cancer cells spread in the bone marrow, with fatal consequences for the patients. Scientists at the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD) and the National Center for…
News • Anemic alternatives
'Bloodless' transfusion could solve global blood shortage
Blood transfusions save lives, yet the precious fluid is in desperately short supply around the globe. But what if transfusions don’t always require blood? A new mathematical model of the body’s interacting physiological and biochemical processes – including blood vessel expansion, blood thickening and flow-rate changes in response to the transfusion of red blood cells – shows that…
News • Hematology
New tabletop analyzer to increase productivity and efficiency in the lab
Clinical diagnostics company Beckman Coulter announced the launch of the DxH 560 AL, a tabletop analyzer geared to reduce the time and resource constraints faced by small to mid-sized laboratories. With the analyzer’s Auto-Loading functionality, closed tube aspiration and walkaway capabilities, users can continually add up to 50 samples, provide safety against blood-borne pathogens and spend…
Article • Blood poisoning
Exploring the importance and challenges of early sepsis diagnosis
On the occasion of this year's World Sepsis Day, we spoke with Elena Sukhacheva, Ph.D., director of medical and scientific affairs at Beckman Coulter, about the status quo and outlook on sepsis diagnostics. With the severity of sepsis symptoms, it’s easy to comprehend why it is invaluable to diagnose this disease properly and in a timely manner. Dr Sukhacheva takes an in-depth look at…
Sponsored • Product of the month
VeinViewer® - Innovation in visualization
The VeinViewer® uses harmless near-infrared (NIR) light which is directed towards the patient’s skin. Haemoglobin in the blood absorbs the NIR and the surrounding tissue reflects it back to the VeinViewer® device, where the data is processed into an image, colour is added and the image sent back to the skin to provide a real time visualization of the blood vessels and patterns up to 10mm…
News • Multiple myeloma therapy
Finding a formula for blood cancer vaccine
Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December. This is the first study to experimentally determine which…
News • Bleeding disorder
Hemophilia: a lot more prevalent than thought
More than 1,125,000 men around the world have the inherited bleeding disorder of hemophilia, and 418,000 of those have a severe version of the mostly undiagnosed disease, says a new study led by McMaster researchers. This is three times what was previously known. Only 400,000 people globally were estimated to have the disorder which is caused by a defect in the F8 or F9 gene which encodes…
News • Stem cell regeneration
Drug accelerates recovery after chemo, radiation
A drug developed by US physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants. The study, published in Nature Communications, also sheds light on the basic biology behind blood…
Sponsored • Haematology analyser
Meet the innovation
The new Yumizen H2500 is a high-end haematology analyser with CBC, 8-DIFF, NRBC, reticulocytes, optical platelets and Body Fluids (CE). Full automation for demanding haematology diagnostics, can be integrated into the Horiba T6000 conveyor belt solution, with the option of a fully-automatic blood smear and staining unit (Yumizen SPS).
News • Blood cell disorder
Promising results for new acute porphyria treatment
Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients. A clinical trial conducted in collaboration with researchers at Karolinska Institutet in Sweden now shows that a new drug…
News • Lab equipment
Horiba launches D-Dimer hematology reagent
Horiba Medical announces the availability of a D-Dimer reagent for their semi-automated Hemostasis instruments. The D-Dimer is a key measurement and the reference exclusion test for the diagnosis of deep vein thrombosis or pulmonary embolism and may also be used for monitoring Disseminated Intravascular Coagulation. The new Yumizen D-Dimer reagent kit is available for Yumizen G hemostasis…
Article • Therapeutic progress
Cancer: riding the wave of innovation
In haematology and medical oncology, there is always something new. However, the increasing stratification of cancer therapies presents an enormous challenge for clinical research. Tumour cells – those altered genetically by mutation and thus ought to be recognised by the immune system and destroyed – manage to apply diverse molecular tricks to avoid attack by the immune system. Thus, they…
Sponsored • POC analysis
A revolution in HbA1c measurement
Quo-Lab® HbA1c is a desktop point-of-care analyzer for measuring glycated hemoglobin (HbA1c). The semi-automated analyzer has been designed specifically to meet the needs of diabetes clinics and laboratories in settings that demand low cost of operation and ease of use. From a simple procedure, Quo-Lab provides lab-accurate test results within four minutes (CV < 3% at 7% A1c) from a venous or…
News • Fully automated coagulation analyzers
HORIBA Medical launches Yumizen G1500/G1550
HORIBA Medical announces that the Yumizen G1500 (open tube) and Yumizen G1550 (closed tube) are now available. These fully automated analyzers can manage the diagnostic and monitoring requirements of clinical laboratories with a mid to high workload. Expanding their field of blood-diseases expertise, directly linked to hematology, HORIBA Medical is now able to offer its customers, dedicated and…
Sponsored • Innovation
Hematology: Advancements and future trends
While the role of the laboratory in disease diagnosis and management has expanded in recent years, causing an overwhelming rise in testing demands, the availability of skilled technologists and specialists has been diminishing. To meet the needs of an overworked and increasingly generalized workforce, today’s products not only must deliver more clinical data than ever before, but also must be…
Article • Hematology
Recommendations on venous blood sampling
Pre-analytics, in particular venous blood sampling has a major impact on the quality of laboratory diagnostic results. An estimated 75 percent of all "lab errors" are caused by errors during pre-analytics. Thus, the German Medical Association’s national guideline on laboratory diagnostics includes detailed guidance on pre-analytics, in particular venous blood sampling. In their…
Article • Patient blood management
Blood transfusions: Patient groups should be precisely defined
Although blood transfusion today is a well-established and safe procedure, the medical science community has not yet arrived at a consensus regarding appropriate patient blood management (PBM) methods. ‘Many PBM approaches have not yet been scientifically validated; consequently over- as well as under-transfusion might be associated with adverse events and complications for the patient,’…
News • RNA sequencing
Overcoming a major barrier to developing liquid biopsies
The idea of testing blood or urine to find markers that help diagnose or treat disease holds great promise. A new study helps set standards for RNA sequencing, improving consistency and laying the foundation to move the field forward.
Video • Medical technology
Genrui presents latest products
Genrui Biotech Inc., one of the leading Chinese developers and manufacturers of IVD equipment and reagents, present their latest POCT devices at the China International Medical Equipment Fair (CMEF). Among the presented devices are the 5-Part Auto Hematology Analyzer KT-6610, which uses advanced tri-angle laser scattering, flow cytometry technology to deliver white blood cell differential…
Article • Assisting algorithms
Big data advances rare disease diagnosis and cancer therapy
Two major projects feeding on big data and based in Spain have recently come under the spotlight: Mendelian, a tool to expedite rare diseases diagnosis, and Harmony, an EU platform that aims to improve targeted therapy in haematological cancer. Rare diseases affect as many as 6% of the Spanish population. Although this percentage is high, these conditions are individually rare, which complicates…
News • Blood coagulation
Molecular switches guide blood forming cells
Scientists from the University of Würzburg successfully elucidated new details about a circuit regulating platelet biogenesis. These important findings could contribute to a better understanding of the mechanism leading to bleeding disorders.
News • Diagnostic equpiment
HORIBA Medical launches auto loading hematology system
In order to enhance its hematology portfolio for the small-mid size laboratories segment, HORIBA Medical has developed a new hematology diagnostic solution. The new Yumizen H550 has been designed to meet the challenging laboratories requirements of providing a cost effective solution based on ‘state of art’ hematology diagnosis combined with user friendly operation.
News • Blood poisoning
"Pulling" bacteria out of blood
Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets. The initial laboratory tests at Empa in St. Gallen have been successful, and seem promising.
