Clinicial chemistry

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News • Chemotherapy

Novel compounds could be less toxic

A novel class of compounds developed by a University of Saskatchewan (U of S)-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer. Team leader Jonathan Dimmock, a medicinal chemistry researcher in the U of S College of Pharmacy and Nutrition, explained their compounds work by interacting with thiols, naturally occurring chemicals that perform several…

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News • Wastewater treatment plants

Analyzer measures chemical oxygen demand

Wastewater treatment plants can benefit from a new chemical oxygen demand (COD) analyzer that will provide plant engineers with another tool to monitor water quality and prevent environmental contamination.COD analysis is used to detect levels of organic pollutants in water, and early identification of these contaminants can indicate an issue in the treatment process of wastewater. The new Thermo…

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News • EKF Diagnostics at AACC

First fully integrated chemistry system

EKF Diagnostics, the global in vitro diagnostics company, announced the international launch of the Altair™ 240 clinical chemistry analyzer at the American Association for Clinical Chemistry’s (AACC) Annual Meeting and Clinical Lab Expo in Atlanta. This new bench-top platform represents EKF Diagnostics’ first fully integrated chemistry system designed for the global market. Also EKF…

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News • Swiss Army Knife for Laboratories

Liquid Chromatography Tandem Mass Spectrometry

During the past 15 years, liquid chromatography tandem mass spectrometry (LC-MS/MS) has evolved into a vital technology used to perform routine tests in many clinical laboratories. Historically, LC-MS/MS had been used primarily by research, pharmaceutical, or commercial laboratories; however, advances in the technology, decreasing costs for basic systems, intelligible software, an increased…

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Article • POCT

Evolutionary POCT

A growing number of clinical tests are being delivered in community hospitals with more patients receiving quicker, accurate diagnoses closer to home, without stays in acute hospital beds. Professor Daniel Lasserson, an Associate Professor in the Nuffield Department of Primary Care Health Sciences at Oxford University, shares the opinion that using point-of-caretesting (POCT) to facilitate high…

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Article • Research

Genetic alterations

This article discusses examples of applications of genetic analyses in coagulation disorders and haematological and oncological diseases. Professor Christine Mannhalter highlights the impact changes have on the occurrence and severity of diseases and their influence on therapy response. Report: Christine Mannhalter

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Article • Antimicrobial stewardship

A diagnostic marker reduces antibiotics use

Since 2009, as part of diagnostic and antimicrobial stewardship strategies, Hampshire Hospitals National Health Service (NHS) Trust has used serum procalcitonin (PCT) – an innovative and highly specific marker to diagnose clinically relevant bacterial infections and sepsis. Report: Mark Nicholls

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Interview • Mass Spectrometry

Connected components are not enough

Bringing liquid chromatography and tandem mass spectrometry (LC-MS/MS) testing into clinical laboratories has been a slow process but continues to show promise to help improve patient care. The medical device industry is on the edge of fundamental breakthroughs that can help drive the adoption into more mainstream clinical laboratories. We recently sat down with Dr Bori Shushan, Mass Spectrometry…

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Article • Cancer diagnostics II

New nanoparticle could enhance MRI scanning

Scientists in the UK have designed a new self-assembling nano­particle that targets tumours and could lead to quicker diagnosis of cancer. Researchers at Imperial College London report that a new self-assembling nanoparticle can adhere to cancer cells, thus making them visible in MRI scans and possibly eliminate the need for invasive tissue biopsies. Report: Mark Nicholls

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Article • Laboratory Medicine

‘Kissed by Europe’

They are not such strange bedfellows, say Walter Depner (Frankfurt) and Professor Norbert Gässler (Hildesheim), who find themselves ‘kissed by the European lab muse’ and were prompted to ask: What links literature and laboratory medicine at a European level? Commentary: Walter Depner, Prof. Norbert Gässler

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