Personalised medicine

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Breast imaging in 2025

A leading radiologist is forecasting a ‘paradigm shift’ in breast imaging. Dr Peter Brader, from Department of Radiology, Division for Molecular and Gender Imaging, Medical University Vienna, envisages that diagnosis and treatment will move from a ‘one size fits all’ approach to one of personalised molecular medicine by 2025. He also foresees greater use of theranostics with combinations…

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Reading tissues

The trend towards personalised medicine implies the development of targeted cancer therapy. Tissue based examinations by pathologists play a key role in this trend. However, the relevance is still underestimated as pathologist Professor Manfred Dietel noted in his lecture at the European Forum on Oncology 2010 in Berlin, which explained what pathology already actually renders to targeted cancer…

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The 3rd Annual General Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry

Different tests bring different results, and results of the same types of test vary from laboratory to laboratory. "In the case of test procedures for autoimmune diseases there are incredible discrepancies," confirmed Professor Manfred Herold, head of the Laboratory for Rheumatism at the University Clinic for Internal Medicine One, Innsbruck. The reason: "There are no standards for…

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RSNA 2010

A double-edged sword would be a good analogy for diagnostic imaging in 2010. New ways to utilise imaging technologies are being developed, imaging equipment is doing more, faster than ever, and image processing software is increasingly innovative. Today's radiology exams are ‘slicing’ through the body to reveal anatomy with increasing clarity for better diagnoses and therapeutic treatment…

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Biomarkers - Keys to prevention and early detection

Biomarkers as the key to prevention and early detection were the subject this autumn at the 7th Annual Congress of the German Society for Clinical Chemistry and Laboratory Medicine (DGKL) in Mannheim. For the DGKL president Professor Karl J Lackner MD, Director of the Institute for Clinical Chemistry and Laboratory Medicine at Johannes Gutenberg University, Mainz, the topic is of increasing…

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„OMICS“ – new buzzword for health policy

“The current shift of healthcare towards a systemic and holistic understanding of the causes of diseases is a true scientific revolution,“ Prof. Dr. Angela Brand said today at the European Health Forum Gastein (EHFG). Prof. Brand, Director of the European Centre for Public Health Genomics hosted at Maastricht University, added that the “next-generation sequencing technologies are opening…

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A bright future for biobanks

Ten years ago, molecular biologist Dr Peter H J Riegman set up a unique bio-bank for medical research at the pathology department of Erasmus Medical Centre, Rotterdam, The Netherlands. The Erasmus MC Tissue Bank now holds 30,000 samples from about 15,000 patients. However, when Dr Riegman discusses his bio-bank with international colleagues they do not immediately associate it with a clinic or…

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Cervical cancer

Data from the ATHENA (Addressing THE Need for Advanced HPV Diagnostics) USA registration trial, involving more than 47,000 women, demonstrate that two human papilloma virus genotypes, HPV 16 and HPV 18, can identify those women with cervical pre-cancer missed by cytologic examination with a Papanicolau (Pap) test.

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Tailoring cancer treatment with biomarkers

New biomarkers play a key role in individualised tumour therapy. They are important indicators for pathological processes in the body and for the use of adequate cancer drugs. In our European Hospital interview Professor Celso A Reis, from the Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP*) in Portugal, discussed the current state of clinical use of…

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Article • Diagnosis, Management, Treatment

EPDA Champions Change for People with Parkinson’s Disease in Europe

To mark the first European Parkinson’s Action Day on April 12th, the European Parkinson’s Disease Association (EPDA) announced the launch of a major new investigation into the care of people with Parkinson’s across 36 European countries. Parkinson’s disease is the second most common progressive neurodegenerative condition which affects people from all around the world.

Nuclear medicine fuses with radiology in joint session

A special feature of this year’s scientific program at ECR 2010 was a joint session organized by the European Association for Nuclear Medicine with the European Society of Radiology. Two speakers representing the EANM took the podium to review developments in nuclear medicine and to challenge colleagues on specific applications.

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The European Network for Cell Imaging and Tracking Expertise (ENCITE)

Since June 2009, the focus of research in the European Network for Cell Imaging and Tracking Expertise (ENCITE) has been on finding biomarkers to aid cell transplantation. Funded with €11 million from the European Commission (EC), this major project that runs until 2013, involves 10 countries. Their work is coordinated by the European Institute for Biomedical Imaging Research (EIBIR) network,…

Exploring a new universe

Molecular imaging, the discipline that unites molecular biology and in vivo imaging technologies to assess biological activity in the body, promises to open up ‘…an entire new universe,’ declared Dr Ralph Weissleder, of the Centre for Molecular Imaging Research at Massachusetts General Hospital, USA, in the journal Radiology. That was just one decade ago. And he was right. It has indeed…

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IQ is strong predictor of cardiovascular disease

While lower intelligence scores have been associated with a raised risk of cardiovascular disease, no study has so far compared the relative strength of this association with other established risk factors such as obesity, smoking and high blood pressure. Now, a large study has found that lower intelligence scores were associated with higher rates of cardiovascular disease and total mortality at…

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The USB health card

Entrepreneur Dr Gunter Pollanz was a central figure in the build-up of charter flights to Israel and in the foundation of MAOF Airlines in Tel Aviv. Later, he also developed important export structures from Israel to Europe. However, in 1997 his life took a dramatic turn when he was diagnosed with lymphoma. Prognosis: Although 54 years old he faced just three more months of life. Today, Dr…

Personalised cancer care

For many years we have heard about personalised cancer treatments, understood each cancer patient is different and that 'one size fits all' treatments are not appropriate. We have been told that early diagnosis is the key to successful treatment and that no two patients have the same genetic or biological profile.

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