Covid-19 disease severity is determined by the individual patient’s immune response. The precise mechanisms taking place inside the lungs and blood during the early phase of the disease, however, remain unclear. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität Berlin have now studied the cellular mechanisms…
La Trobe University researchers are the first in the world to characterize precisely how Covid-19 attacks lung tissues — an important step in preventing long-term damage.
Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have published the first detailed atomic-level model of the SARS-CoV-2 "envelope" protein bound to a human protein essential for maintaining the lining of the lungs.
Communities benefit from sharing knowledge and experience among their members. Following a similar principle - called “swarm learning” - an international research team has trained artificial intelligence algorithms to detect blood cancer, lung diseases and Covid-19 in data stored in a decentralized fashion. This approach has advantage over conventional methods since it inherently provides…
Body composition information derived from routine chest CTs can provide important information on the overall health of people with chronic obstructive pulmonary disease (COPD), including their risk of all-cause mortality. This is the result of a new study, published in Radiology. COPD is a group of chronic, progressive lung diseases that affect about 30 million people in the United States alone.…
The results of a large-scale study indicate that the introduction of an AI-powered solution by healthcare software company Radlogics into radiology workflow to analyze Chest-CT scans during the Covid-19 pandemic reduced report turnaround time by an average of 30 percent, which is equivalent to 7 minutes per case.
Beta-glucan tests are proving to be pivotal in the better detection and diagnosis of fungal infections. As a robust complimentary test for traditional testing techniques and biomarkers, it is helping clinicians deliver rapid results and offering greater reassurance in more accurately identifying such infections. β-glucan testing, which is an in vitro diagnostic test, is regularly used at…
Healing the body with cells – this is the ambitious goal of scientists at Hannover Medical School (MHH). With this in mind, Professor Dr. Nico Lachmann and Dr. Robert Zweigerdt have initiated a research collaboration and license agreement with the pharmaceutical company Novo Nordisk A/S, to combine academic knowhow with the translational power of the industry. The overall aim of the endeavor is…
The Belgian initiative icovid, which supports radiologists in the assessment of CT images of the lungs of COVID-19 patients, has grown into a multicentre European project, co-funded by the EU Horizon 2020 programme. Icovid was set up in March by UZ Brussel, KU Leuven, icometrix and ETRO, an imec research group of VUB.
An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage. In a new study, scientists identified a molecule that is produced by immune cells during mechanical ventilation to try to decrease inflammation, but isn’t able to completely prevent…
Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body’s immune system within the first few days of the illness. But in a study published in Nature, investigators at Northwestern Medicine show Covid-19 pneumonia is…
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for Covid-19, among other diseases.
Covid-19 causes characteristic changes in lung tissue visible in CT scans and chest radiographs, known as “ground-glass” opacities. Imaging is now considered a valid alternative, possibly even superior to RT-PCR. ‘This sparked an international debate about the role of CT in the diagnostic work-up of Covid-19,’ said radiologist Professor Cornelia Schäfer-Prokop.
RSNA 2020: International experts showcased new studies on chest CT’s role in Covid-19 diagnosis and treatment. A staggering volume of work and has been produced on the pandemic this year, with an average 367 Covid-19 journal articles published per week, according to Michael Chung, Assistant professor of radiology at Icahn School of Medicine at Mount Sinai, NYC.
Low, light and with a field strength: 0.55-tesla with added new digital technologies. Indeed, this is a very new class of MRI scanner created by Siemens Healthineers. We interviewed Christiane Bernhardt, Vice President of Magnetic Resonance Marketing & Sales, Business Line MR, at Siemens Healthineers, about the technologies behind this development, plus its advantages and applications.
Chronic illnesses can have a dramatic impact on a patient's later life. An early diagnosis of such diseases opens up the possibility of taking medical action in good time.
Wearable ultrasound sensors can help patients monitor their lung health from their own homes. The potential application of this technology were outlined in a session at MEDICA 2020.
Costantino Balestra, Professor of Physiology at Haute Ecole Bruxelles-Brabant in Belgium, uses point-of-care ultrasound (POCUS) in environments that could not be more different from a typical hospital setting. His expertise lies in studying the effects of extreme conditions on the human body, including temperatures, altitudes, and ambient pressures, for example, in deep oceans. One of his areas…
‘Mini-lungs’ grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs. Writing in the journal Cell Stem Cell, the researchers detail the mechanisms underlying SARS-CoV-2 infection and the early innate immune response in the lungs.
Scientists at EPFL are using technology to better understand how coronavirus causes blood clots in some patients. They have developed a simplified model of a lung that lets them observe, for the first time, how the virus attacks the cells lining blood vessels.
Scientists have unearthed a possible link between the severity of COVID-19 and air quality. The preliminary study – looking at whether areas with higher levels of air pollutants in England are associated with a larger number of cases/deaths from COVID-19 – was conducted by a team from the University of Cambridge. Aware of the effects that air pollutants have on human health – and that…
Around 550 million people have chronic obstructive pulmonary disease (COPD), according to two University of Manchester medical students. The figure more than doubles the previous estimate of 251 million people with the illness linked to smoking by the World Health Organization (WHO) Global Burden of Disease Study. The University of Manchester students, Emily Hammond and Charles McDonald, made the…
A recent preprint study in France underpins the debate on whether lung ultrasound (LUS) should be used to triage COVID-19 patients better at the hospital as well as in primary care. The eChoVid study, published as a preliminary report of work on medTrix, shows that LUS enables identification of lung lesions as well as chest CT in COVID-19 patients. A team of French researchers compared routinely…
COVID-19 patients can suffer long-term lung and heart damage but, for many, this tends to improve over time, according to the first, prospective follow-up of patients infected with the coronavirus, presented at the European Respiratory Society International Congress. [1]
Babies born with higher levels of cadmium in their umbilical cord blood may be more likely to develop childhood asthma and allergies, according to research presented at the European Respiratory Society International Congress. (1)