News • Inexpensive invention
Test kit enables quick and accurate screening of diseases
Test results are denoted by a colour change and could be further analysed by a smartphone app, making it attractive as a point-of-care diagnostic device.
Infections
News • mini viral RNA
Understanding the deadly nature of pandemic influenza
Researchers at the University of Cambridge and the University of Oxford have discovered a new molecule that plays a key role in the immune response that is triggered by influenza infections.
News • Scientific breakthrough
New accelerated diagnosis of multi-resistant hospital pathogens
A team of researchers at the University of Cologne's Faculty of Medicine and the German Center for Infection Research (DZIF) use a novel immunochromatographic method to detect bacteria that are resistant to the antibiotic group carbapenemes within 20 to 45 minutes from blood cultures with 100 percent certainty.
News • Infections
Zika virus strips immune cells of their identity
Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.
News • Therapy
Could these special antibodies lead to HIV vaccine?
Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. Researchers from the University of Zurich and the University Hospital Zurich have now shown that the genome of the HI virus is a decisive factor in determining which antibodies are formed.
News • World Sepsis Day 2018
Beckman Coulter sponsored 2nd World Sepsis Congress
Beckman Coulter was a gold sponsor of the 2nd World Sepsis Congress, a free-of-charge online conference, hosted by the Global Sepsis Alliance, that took place on Sept. 5 and 6, 2018. Over the course of 17 sessions, more than 100 speakers from approximately 30 countries discussed the wide-ranging implications of sepsis and how to raise public awareness of this often-fatal condition.
News • Research
Zika virus proteins inhibit brain development
In healthy individuals, the Zika virus causes flu-like symptoms. If a pregnant woman becomes infected, the unborn child can suffer from severe brain abnormalities as a result of mechanisms that have not yet been explained. A study by the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry (MPI-B) shows that Zika virus proteins bind to cellular proteins that are…
Sponsored • Fungal testing
One test winning over a run of 10 New β-Glucan test delivers rapid results
Fungal testing plays a critical role in patient care. However, the turnaround for results can be lengthy because the existing tests need 10 samples in a run. Professor Maurizio Sanguinetti, Professor of Microbiology at the Catholic University of the Sacred Heart (Università Cattolica del S. Cuore), in Rome, Italy, is comparing the results of a new test with those from existing tests. Created by…
News • Infectious disease
Evolution of leading cause of malaria outside of Africa
The genome sequences of ape parasites related to Plasmodium vivax (P. vivax), the main source of mosquito-borne malaria outside Africa, provide insights on the origin and early evolution of the human parasite. This finding could have implications for better comprehending and eradicating malaria infection worldwide.
News • Infections
Reliable point-of-care blood test can help prevent toxoplasmosis
A recent study, performed in Chicago and Rabat, Morocco, found that a novel finger-prick test for infection with the parasite Toxoplasma gondii during pregnancy — and many other potential applications — is 100 percent sensitive and 100 percent specific for detecting the presence of this life-damaging microorganism.
News • Autophagy
Pathway Ebola virus uses to enter cells pinpointed
The new outbreak of the deadly Ebola virus declared just last week in eastern Democratic Republic of Congo is believed to have claimed more than 30 victims so far, highlighting the continued urgency to find a way to stop the pathogen from killing the people it infects. A new study is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to…
News • Mysterious illness
Potential diagnostic test for Kawasaki disease
For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory…
News • Henipaviruses
Lethal viruses hijack cellular defences against cancer
Monash University’s Biomedicine Discovery Institute (BDI) researchers have identified a new mechanism used by Henipaviruses in infection, and potential new targets for antivirals to treat them. Their findings may also apply to other dangerous viruses.
News • Diagnostic lab system
DxM MicroScan WalkAway System now available on the market
Beckman Coulter announced commercialization of its DxM MicroScan WalkAway system, a diagnostic solution for bacterial identification and antibiotic susceptibility testing for microbiology laboratories. The DxM MicroScan WalkAway system uses direct minimum inhibitory concentrations (MIC) for detection of antimicrobial resistance, offering greater confidence in results through gold-standard…
News • T cell response
Scientists find out what makes people survive Ebola
Scientists conducting the first comprehensive study of key immune system cells—collected from West African Ebola survivors— have made a surprising discovery that provides important clues to developing effective vaccines against the infection.
News • Air disinfection and purification device
Closing the infection control loop
Novaerus, an Irish company specialising in non-chemical air disinfection using patented ultra-low energy plasma, announced the launch of the Defend 1050, a portable, easy to use device ideal for rapid disinfection and purification of the air in large spaces and high-risk situations such as operating theatres, ICUs, IVF labs, emergency and waiting rooms, and construction zones.
News • Klebsiella pneumoniae
Biomarker is discovered for a flesh-eating pathogen
Imagine a pathogen that infects completely healthy people and can cause blindness in one day and flesh-eating infections, brain abscesses and death in just a few days. Now imagine that this pathogen is also resistant to all antibiotics.
News • Smart pill
Swallowed sensor sends signal if you’re sick
Researcher have created an ingestible sensor to non-invasively monitor indicators of disease in the stomach and intestines.
News • Infections
Zika suppresses virus fighting cells
More than two years after reports of skyrocketing Zika rates surfaced worldwide, questions still loom about this complicated virus. Professor of Biological Science Hengli Tang and his postdoctoral researcher Jianshe Lang from the Florida State University take a deep dive into the differences between Zika and the Dengue virus.
News • Epidemics
Animal health drug could stop outbreaks of malaria and Zika virus
Medicines given to household pets to kill fleas and ticks might be effective for preventing outbreaks of malaria, Zika fever and other dangerous insect-borne diseases that infect millions of people worldwide, according to a new study led by scientists at Calibr, a non-profit drug discovery institute closely affiliated with Scripps Research and TropIQ Health Sciences, a Dutch social enterprise.
News • Research
Gene discovery unlocks mysteries of our immunity
Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.
News • New major epidemics?
Two gene mutations transform harmless bacteria into dangerous strains
Since 2013, a new strain of meningococcal bacteria has spread rapidly in Niger and Nigeria, leading to large-scale outbreaks of meningitis. Analysis of the genetic material shows that with just two gene mutations, harmless bacteria transform into a strain that could cause major epidemics in these two countries.
News • Therapy
A 'super' receptor that helps kill HIV infected cells
While treatments for HIV mean that the disease is no longer largely fatal, the world still lacks a true therapy that can eradicate the virus across a globally—and genetically different—population.
News • When the phosphate decides...
Defense against viruses or autoimmune disorder?
The first defense line of the body against virus infections is composed of so-called restriction factors. SAMHD1, one of such restriction factors, does not only play a role in the defense against viruses but also in the development of autoimmune disorders and cancer. The question of which effect SAMHD1 exertsin the cell is decided by addition or removal of phosphate groups.
News • Infections
Tuberculosis: new substance to counteract antimicrobial resistance
Antimicrobial resistance is on the rise worldwide. This is becoming a problem for infectious diseases like tuberculosis as there are only a few active substances available to combat such diseases. Pharmacists at Martin Luther University Halle-Wittenberg (MLU) have now found a way to increase the efficacy of a common tuberculosis agent while, at the same time, reducing resistance to it. The…