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Article • Automation

Mass spectrometry is advancing laboratory practice

Mass spectrometry is moving laboratory medicine to increasingly automated discrete analysis methods, resulting in ever faster and more reliable results. It is also leveraging economies of scale as an increasingly cost-effective tool, says Craig Webster, Consultant Clinical Scientist and Clinical Lead, Department of Biochemistry and Immunology at Heartlands Hospital in Birmingham. Speaking about…

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Article • Economies of scale

Lab medicine: Network consolidation continues

Laboratory networks are consolidating across the globe as they seek to deliver a more efficient and cost effective service. The latest developments on several continents were outlined at the FiLM 2018 – Frontiers in Laboratory Medicine congress held in Birmingham, UK in January. With consolidation viewed as a way to deliver economies of scale, it was a recurring theme at the congress with…

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Interview • Clinical practice

LC-MS/MS enters the medical laboratory

Over the last four years, Dr Thomas Stimpfl and his team have integrated mass spectrometry into routine analysis. The analytical technique liquid chromatography–mass spectrometry (LC-MS) combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analytical capabilities of mass spectrometry (MS). LC- and MS procedures were not originally developed for…

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Article • Mass spectrometry

Analytics meets diagnostics

Up to the early 16th century, essentially medical diagnostics was limited to uroscopy – the observation of a urine sample in a uroscopy flask with a candle providing light. One hundred years later, the first microscopes were developed and from then on the development of technical devices and instruments boomed. Combining chromatography instruments and mass spectrometers began with the sole…

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Sponsored • Manufacturers vs. bureaucracy

‘We will master this problem’

Manufacturers are required to prevent so-called anomalous use. This includes, for instance, the use of cuvettes that are not licensed in products like Teco’s Coatron-X. Norms and directives are the backbone of medical devices manufacture. Frequent updates keep them current, but also often create unforeseen problems, especially for smaller and medium-size companies, because the bureaucracy is…

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News • Immunoassay and clinical chemistry analyzers

This is why laboratories worldwide adopt the Atellica Solution

LBM Bioesterel in France, Arcispedale S. Maria Nuova in Italy and Friarage Hospital in the United Kingdom are among the first laboratories to install the Atellica Solution immunoassay and clinical chemistry analyzers. The trending motivators for installing the latest innovation from Siemens Healthineers include the unprecedented flexibility to automate redundant and complex procedures to simplify…

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News • Point-of-care testing

HORIBA Medical’s unique POC CRP analyser reducing unnecessary admissions

HORIBA UK Ltd, Medical announces that Thame and Marlow Community Hubs, within Buckinghamshire Healthcare NHS Trust, have each recently installed HORIBA Medical’s latest point-of-care testing analyser, the Microsemi CRP. These new analysers are now streamlining existing diagnostic pathways in the community and helping to reduce local A&E admissions for frail patients. The Microsemi CRP is a…

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News • Clinical diagnostics

SCIEX launches high-performance mass spectrometry technology

SCIEX Diagnostics, the in vitro diagnostics division of SCIEX, a global leader in mass spectrometry in the life sciences industry, announced the launch of the Citrine Triple Quad MS/MS and Citrine QTRAP MS/MS systems for clinical diagnostics. The Citrine system is designed specifically to meet the unique needs of clinical labs that require maximum sensitivity, the highest throughput, a wide…

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News • Breast biopsy

Hologic's Brevera system receives European CE mark

Hologic, Inc. announced it has obtained a CE Mark in Europe for the Brevera breast biopsy system with CorLumina imaging technology, a groundbreaking real-time breast biopsy and verification system that improves the patient experience and streamlines the biopsy process from start to finish. The first-of-its-kind Brevera system is designed to increase biopsy accuracy with real-time imaging that…

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Article • Improved workflow

UK uptake increases in digital pathology

Professor Jo Martin, the newly-appointed President of the Royal College of Pathologists in the United Kingdom, believes the National Health Service (NHS) is on the brink of embracing digital pathology more widely. A number of UK laboratories, he explained, are adopting digital pathology in histopathology – in line with some labs in Sweden and Holland, where it has become routine – and the…

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Article • New display and calibration kit

Accurate colour augments pathology diagnostics

Digital pathology places particularly high demands on image quality and thus on monitors. Especially the exact colour rendering is a challenge – no other discipline needs such precision for a reliable diagnosis. To that end, following ‘intensive research and development’, JVC Kenwood has launched the JD-C240, a 24.1-inch colour monitor.

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Article • Breast cancer detection

New DNA test could prevent thousands of mastectomies

A new genetic test to assess breast cancer risk in women who have a family history of the disease could be introduced into clinical practice in the UK within the next few months. Devised at Manchester University NHS Foundation Trust (MFT) and the University of Manchester, researchers believe the test for high-risk groups could also help reduce the number of women needing to have surgery to remove…

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Article • Analytics meets diagnostics

A brief history of mass spectrometry

Up to the early 16th century, essentially medical diagnostics was limited to uroscopy – the observation of a urine sample in a uroscopy flask with a candle providing light. In a visual examination the doctor would determine the colour of the urine as well as cloudiness and precipitates, followed by a smell and taste test. The information he gathered provided the basis of his diagnosis. 100…

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Video • LIMA project

Agena Bioscience’s liquid biopsy technology awarded Horizon 2020 grant

Agena Bioscience, a global provider of molecular genetic solutions, announced it has been selected to participate as an innovative technology provider in the ‘Liquid biopsies and IMAging for improved cancer care’ (LIMA) project. The LIMA project has been awarded a EUR 6.3 million Horizon 2020 European Union research grant to develop an integrated approach for personalized cancer treatment.…

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Article • Digital Pathology

Deep learning and AI progress

Early adoption of image analytical tools and artificial intelligence (AI) are crucial if health systems across Europe are to see the full potential of digital pathology, according to leading expert Professor Johan Lundin, Research Director at the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki. Although European institutions increasingly embrace digital pathology, he…

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News • Microtechnologies and automated systems

How emerging tech can help identify bacteria and antibiotic susceptibility

An SLAS Technology review article by Yiyan Li, Xing Yang and Weian Zhao of University of California, Irvine highlights and synthesizes representative emerging micro- and nanotechnologies, as well as automated systems for bacterial identification (ID) and antibiotic susceptibility testing (AST), including both phenotypic and molecular methods and those at the point-of-care (POC) setting. Also…

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News • Direct from whole blood samples

LiDia demonstrates rapid and sensitive BSI identification

DNAe, the inventor of semiconductor-based genomic analysis technologies, and the developer of a new, game-changing test for bloodstream infections that can lead to sepsis announced new data on its test for bloodstream infections, LiDia BSI. The data demonstrates the ability of the LiDia BSI closed cartridge-based test to rapidly identify low levels of bacterial and fungal pathogens and resistance…

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News • POC hemoglobin analyzer

EKF introduces mobile data management solution

EKF Diagnostics, the global in vitro diagnostics company, introduces POC Connect - a data management smartphone application for its DiaSpect Tm hemoglobin analyzer. At Medica 2017 on Stand H3/C70, EKF will be highlighting how DiaSpect Tm is the only reagent-free hemoglobin analyzer with mobile connectivity. Lightweight and palm-sized, the DiaSpect Tm analyzer delivers laboratory quality…

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Article • Refined capillary blood collection

Small tubes, great impact

The capillary blood collection system not only benefits geriatric patients, or those who need regular blood sampling, but also burns victims and others, including the youngest patients. All need a gentle approach. To that end, Austrian firm Greiner Bio-One has developed and optimised its MiniCollect system.

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Article • Point-of-care testing

Advancing lateral flow immunoassays

‘Lateral flow immunoassays (LFIs) have evolved rapidly in the past 30 years, from the original crude and simple qualitative tests, to more complex multi-analyte and quantitative assays,’ reports BBI Solutions, a firm that has been raising the performance of lateral flow tests with the development of technologies for next generation diagnostics.

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Article • Gene editing

CRISPR system embeds images in DNA

A research team in the United States has developed a revolutionary technique that has encoded an image and short film in living cells. Scientists at the Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) used CRISPR gene editing to encode the image and film in DNA, using this as a medium to store information and produce a code that relates to the individual…

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