Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
Clinicians tend to disregard patient self-assessments for their diagnostic decisions, new research suggests – a mistake that might cause those patients unnecessary harm.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
A large epidemiological study shows that patients with an autoimmune disorder have a substantially higher risk of developing cardiovascular disease than individuals without autoimmune disease.
Autokit CH50 Assay is an in vitro diagnostic (IVD) test for the quantitative determination of total complement activity in human serum. The complement system is a part of the immune system that enhances/complements the ability of antibodies and phagocytic cells to clear pathogens from an organism.
Pregnancy complications and early menopause increase women’s future risk of heart disease. Cardiologists, gynaecologists and endocrinologists recommend how to help middle-aged women prevent later heart problems in a European Society of Cardiology (ESC) consensus document published in European Heart Journal, a journal of the ESC.
September: Basel, Switzerland: ‘Intelligent Health 2019’, a conference dedicated to artificial intelligence (AI) in medicine, underlined the growing interest by the rising number of attendees – 1,400 in 2018, its first year, to 2,027 this year. With examples of AI use from around the world, the common thread throughout was how AI can serve humankind by enabling better understanding of…
Fungal testing plays a critical role in patient care. However, the turnaround for results can be lengthy because the existing tests need 10 samples in a run. Professor Maurizio Sanguinetti, Professor of Microbiology at the Catholic University of the Sacred Heart (Università Cattolica del S. Cuore), in Rome, Italy, is comparing the results of a new test with those from existing tests. Created by…
Weak, easily broken bones are an epidemic in the United States. They’re often tied to osteoporosis, a disease that causes bones to degenerate over time. This makes them less flexible, more brittle, and easier to break. According to the International Osteoporosis Foundation, more than 44 million Americans aged 50 and older either have or face the threat of developing osteoporosis due to low bone…
A far-reaching study conducted by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV)—best known for causing mononucleosis—also increases the risks for some people of developing seven other major diseases.
Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic. In a new publication in the Annals of Rheumatic Diseases, Evseenko’s team describes the promise of a new molecule aptly named “Regulator of Cartilage Growth and Differentiation,” or RCGD…
A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy. When exposed to Zika virus before birth, mouse fetuses with the protein commit cell suicide, while fetuses without it continued to develop. The result, published in Science Immunology, suggests that the protein, a receptor involved in immune cell signaling, plays a role in spontaneous abortions and other human…
Researchers have evidence that specialized T cells are vulnerable to exhaustion that may contribute to allergic reactions.
Authors Guiseppe Lippi, Chiara Bovo and Emmanuel J. Favaloro offer a glimpse into a new generation of hematology analyzers and discuss the concepts of redesigning coagulation analyzers to fit the most important aspects of the preanalytical, analytical and postanalytical phases in hemostasis testing. The aim of this opinion article is to provide some personal ideas, based on experience and…
Researchers at Hospital for Special Surgery (HSS) have uncovered a potential genetic trigger of systemic autoimmune disease. The study, the culmination of more than 10 years of research, discovered virus-like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome.
Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.
Silicone breast implants are the most popular type of implant. The postulated relation between silicone breast implants and the risk of connective tissue and autoimmune diseases has generated intense medical and legal interest during the past decade. Considerable controversy has surrounded the long-term safety of silicone breast implants.
It’s a war against a perceived enemy that is not – autoimmune disease like rheumatoid arthritis, lupus erythematosus or multiple sclerosis, occur when the immune system attacks normal tissue components. Characteristic of those disease patterns are autoantibodies in the blood, which the immune system produces to attack its own organism.
Different tests bring different results, and results of the same types of test vary from laboratory to laboratory. "In the case of test procedures for autoimmune diseases there are incredible discrepancies," confirmed Professor Manfred Herold, head of the Laboratory for Rheumatism at the University Clinic for Internal Medicine One, Innsbruck. The reason: "There are no standards for…
Researchers from University Hospital in Umea, Sweden, have identified several cytokines, cytokine-related factors, and chemokines that increase significantly prior to rheumatoid arthritis (RA) disease onset. These findings confirm those of earlier studies which suggest that the risk of developing RA can be predicted and disease progression may be prevented. Complete findings of this study are…
The foundation of the AESKU.KIPP Institute, based in Wendelsheim, Germany, presents a platform to initiate and co-ordinate international auto-immunity research projects.