Article • Mini Microscopes
Mobile technology could enhance digital pathology
Mobile technology could prove an important catalyst in helping take digital pathology onto a new level in delivering clinical diagnostics.
Studies
Sponsored • Automated DIA
Use the digital image analysis in Breast Cancer
In a study of 436 breast cancer cases with 28 years of survival data histo-pathologists from Karolinska Institute, Stockholm, Sweden shows that protein tissue-based biomarker data are at least as good as gene expression assays.
Partners in crime: Stroke and Alzheimer’s disease
New EU-funded project CoSTREAM targets the common mechanisms and pathways of stroke, Alzheimer’s disease to improve disease prevention and treatment, by combining clinical, genetic, epidemiologic, metabolic and radiologic research to develop an organ-on-a-chip in vitro model for the blood-brain connection that will revolutionise drug-development.
Article • Datasets
Benefits from The Cancer Genome Atlas
Last year, scientists at the University of California San Francisco (UCSF) revealed that by measuring the proportion of both immune and cancerous cells in tumours, or ‘tumour purity,’ clinicians could more precisely predict the success of certain precision therapies. A key aspect of the discovery was access to over 10,000 samples constituting 21 different cancers.
News • Diagnosing Pneumonia
Is lung ultrasound a safe substitute for chest X-Ray?
Lung ultrasound has been shown to be highly effective and safe for diagnosing pneumonia in children and a potential substitute for chest X-ray, according to a study conducted at the Icahn School of Medicine at Mount Sinai.
News • Successful dying
Researchers define the elements of a “Good Death”
For most people, the culmination of a good life is a “good death,” though what that means exactly is a matter of considerable consternation. Researchers at the University of California, San Diego School of Medicine surveyed published, English-language, peer-reviewed reports of qualitative and quantitative studies defining a “good death,” ultimately identifying 11 core themes associated…
News • Women and Men
Heart Disease: same symptoms, different care
Despite messages to the contrary, most women being seen by a doctor for the first time with suspected heart disease actually experience the same classic symptoms as men, notably chest pain and shortness of breath, according to a study led by the Duke Clinical Research Institute.
First injectable nanoparticle generator to fight breast cancer
A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.
News • Clinical trial results
Reporting by top academic centers remains poor
Dissemination of clinical trial results by leading academic medical centres in the United States remains poor, despite ethical obligations - and sometimes statutory requirements - to publish findings and report results in a timely manner, concludes a study in The BMJ.
News • Antibodies
A ‘silver bullet’ for Ebola viruses?
There may be a “silver bullet” for Ebola. Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch in Galveston (UTMB) reported that they have isolated human monoclonal antibodies from Ebola survivors which can neutralize multiple species of the virus.
HUS, Finland, undertakes clinical study of Carestream Cone Beam CT
HUS Medical Imaging Center, based in Helsinki, Finland, is undertaking the first European clinical test study of the new CARESTREAM OnSight 3D Extremity System in pre- and post-operative cases. The study of the new cone beam CT (CBCT) scanner and image reconstruction technology, applied within orthopaedic imaging, will last six months and will yield valuable data for both HUS and Carestream…
News • Body dysmorphic disorder
Online therapy can help
Internet based cognitive behavioural therapy (CBT) can help people affected by body dysmorphic disorder, finds a study published by The BMJ today. This is the largest clinical trial of body dysmorphic disorder ever conducted, and the first to evaluate the effect of an internet based programme for the condition.
News • Experts argue
Cancer screening does not “save lives”
Harms of screening are certain, but benefits in overall mortality are not … “We must be honest about this uncertainty,” experts say. Cancer screening has never been shown to “save lives” as advocates claim, argue experts in The BMJ.
News • σ=p*r/2h
Physics Law Applied to Improve Left-Sided Heart Failure
Cardiologists from 15 centers in 6 countries have evaluated a new approach for the treatment of Left-Sided Heart Failure under the leadership of Stefan D. Anker, MD, Ph.D., Professor of Innovative Clinical Trials at the Cardiology and Pulmonology Clinic in the Heart Center of the Medical University Göttingen (UMG). The investigators in the clinical evaluation entitled AUGMENT-HF demonstrated…
News • fMRI
Scientists localise the Christmas spirit in the brain
Understanding how the Christmas spirit works could be a powerful tool in treating the "bah humbug" syndrome. The Christmas spirit has been located in the human brain, reveals a study published in The BMJ's Christmas issue.
When rejection comes from within
A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre (CRCHUM.)
Multiple sclerosis can be triggered by brain cell death
Multiple sclerosis (MS) may be triggered by the death of brain cells that make the insulation around nerve fibers, a surprising new view of the disease reported in a study from Northwestern Medicine and The University of Chicago.
News • There's an app for that
An easy, fast and reliable way to record causes of death
Researchers from the University of Melbourne have developed a revolutionary new app to capture accurate global cause of death data on tablets and mobile phones.
News • Study
A biomarker for multiple sclerosis
Patients with multiple sclerosis often receive a "hit and miss" treatment when the disease breaks out. A blood analysis is now for the first time able to reveal which of the two most important first-line drugs is better suited for which patients.
Danish study: Depression contributes to preventable hospitalizations
Individuals with depression are more than twice as likely to have hospitalizations that might be preventable with timely outpatient medical care in the community, a new study finds.
Testosterone replacement makes Type 2 diabetic men more sensitive to insulin
Findings demonstrate that testosterone is a metabolic hormone as well as a sex hormone, University at Buffalo researchers say.
Article • Mortality
Death risk rises over weekends
New studies reveal the heightened risk of death that patients face if admitted to hospital over a weekend. Researchers have studied what effect the day of hospital admission has on death rates across England in 2013-2014, as well as on hospitals in other countries, such as Australia, the USA and The Netherlands. Report: Mark Nicholls
Article • Infection
Trial pitches MGB-BP-3 against clostridium difficile
Scientists at the University of Strathclyde in Glasgow have been working to identify compounds with important anti-infective activity and suitable for treating serious infectious diseases caused by bacteria and parasites, such as Clostridium difficile. Their work has led to the creation of the new drug known as MGB-BP-3 (MGB = minor groove binder). Report: Mark Nicholls
News • Detection
QuantiPlasma antibodies for early lung cancer diagnostics licenced
Randox Laboratories and Biosystems International have announced the beginning of clinical validation of a lung cancer early detection test.
Article • Telecardiology
Home monitoring in fast action
Every year, worldwide, over a million patients have a pacemaker or defibrillator implanted. Home monitoring systems can significantly improve the safety and quality of life for these patients, says Professor Gerhard Hindricks, head physician in the rhythmology department at Leipzig’s Heart Centre. Report: Sascha Keutel
