Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore's MinIONTM device, a genome sequencer that can fit in the palm of your hand.
“I am very concerned about the impact that Angelina Jolie has on the media,” Walter Rocca, professor of epidemiology and neurology at the Mayo Clinic in Rochester, Minnesota, stated. He wasn’t hinting to Jolie’s acting choices or waifish silhouette, but to the confusion surrounding her decision to remove her ovaries to prevent ovarian cancer. By Mélisande Rouger
Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress. This gene may also be an Achilles' heel when treating certain tumors, according to a team of researchers at The University of Texas MD Anderson Cancer Center.
A single dose of an FDA-approved intravenous nutrition source may be able to significantly reduce the toxicity and increase the bioavailability of platinum-based cancer drugs, according to a study by Carnegie Mellon University biologists published in Scientific Reports.
Patience and persistence are beginning to pay off for University of Montana Professor Mark Grimes, whose research about the behavior of cell proteins in childhood cancer recently was published by the Public Library of Science Computational Biology.
A global collaboration to expand access to advanced particle therapy worldwide was agreed this April between Belgian firm IBA (Ion Beam Applications S.A.) and the Toshiba Corporation.
Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.
In certain types of cancer, nerves and cancer cells enter an often lethal and intricate waltz where cancer cells and nerves move toward one another and eventually engage in such a way that the cancer cells enter the nerves.
Scientists in the UK have designed a new self-assembling nanoparticle that targets tumours and could lead to quicker diagnosis of cancer. Researchers at Imperial College London report that a new self-assembling nanoparticle can adhere to cancer cells, thus making them visible in MRI scans and possibly eliminate the need for invasive tissue biopsies. Report: Mark Nicholls
Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad.
Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn’t cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.
Researchers at the San Diego Supercomputer Center (SDSC) and the Moores Cancer Center at the University of California, San Diego, have described for the first time the molecular mechanism of cancer development caused by well-known "resistance" mutations in the gene called epidermal growth factor receptor (EGFR).
Cells have two different programs to safeguard them from getting out of control and developing cancer. One of them is senescence (biological aging). It puts cancer cells into a permanent sleep so they no longer divide and grow in an uncontrolled way. Now the research group led by Professor Walter Birchmeier (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch) has discovered that an…
40 percent of people in the EU suffer from non-alcoholic steatohepatitis, a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society.
The ‘MRI of the Adnexa, Essentials and Beyond’ session from at the MR 2015 symposium held in Garmisch, Austria, presented tips and tricks in clinical routine before moving to research that combines imaging and genomic data to better evaluate ovarian cancer. Report: John Brosky
Molecular profiling is transforming brain cancer management and radiologists must get to grips with the upcoming paradigm that will affect the way they report findings. Renowned neuroradiologist Professor Anne G. Osborn from the University of Utah, School of Medicine, Salt Lake City, unveiled the latest advances in brain pathology during the Nikola Tesla Honorary Lecture last week at ECR…
Spring can be felt, though many visitors of ECR 2015 probably only have time to enjoy the floral decorations in the conference center. The program of the conference is packed full of topics that promise exciting days and many discussions.
People have highly variable views on how much overdetection is acceptable in cancer screening, finds a UK survey. The authors say invitations for screening "should include clear information on the likelihood and consequences of overdetection to allow people to make an informed choice."
A surgical algorithm developed and implemented by ovarian cancer specialists at The University of Texas MD Anderson Cancer Center dramatically increases the frequency of complete removal of all visible tumor - a milestone strongly tied to improved survival.
Findings of a recent study say that environmental stress is a major factor for DNA damage and therefore the reason for accelerated tissue aging and probably cancer. Good sleep prevents this DNA damage.
Researchers at University Medical Center (UMC) Utrecht are developing an innovative cancer treatment with the help of a grant from Alpe d’HuZes/Dutch Cancer Society (KWF) of nearly 300,000 euros. The treatment involves the injection of radioactive beads into tumors, thereby enabling a very precise localized radiotherapy.
Carestream will show enhancements to its digital breast tomosynthesis (DBT) module including a slabbing tool, improved workflow capabilities and the display of DICOM-compliant 2D synthetic views (which are generated from the 3D dataset) at the 2015 European Conference of Radiology. The latest DBT module is currently available.
Researchers at the Hubrecht Institute and the University Medical Center (UMC) Utrecht successfully developed a culturing system for human liver stem cells as well as stem cells from pancreatic cancer. They describe the development of these culturing systems in two articles in this week’s edition of Cell magazine.
The term ‘cancer’ describes more than 200 different diseases and every single one needs to be clearly understood and requires, ideally, individual treatment. To do this we need to deepen our understanding the cancer genome. Report: Anja Behringer
Scientists from the German Cancer Research Center in Heidelberg and from the Medical Faculty Mannheim of Heidelberg University treated mice with a combination of a low-dose metronomic chemotherapy and an antibody against Ang-2, a regulatory protein of the blood vessel lining cells. The treated animals had significantly less metastases.