Infections

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News • Molecular Genetics

How a Bacterial Cell Recognizes its Own DNA

It may come as a bit of a surprise to learn that bacteria have an immune system – in their case to fight off invasive viruses called phages. And like any immune system – from single-celled to human – the first challenge of the bacterial immune system is to detect the difference between “foreign” and “self.” This is far from simple, as viruses, bacteria and all other living things…

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Article • UTI pathogen

Boosting the Body’s Natural Ability to Fight Urinary Tract Infections

Urinary tract infections (UTIs) are common, and widespread antibiotic resistance has led to urgent calls for new ways to combat them. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that an experimental drug that stabilizes a protein called HIF-1alpha protects human bladder cells and mice against a major UTI…

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Article • Infectious diseases

Carrying home a nosocomial infection

About 6-8% of Spanish patients will develop an infection during or after a hospital stay. Can these infections be avoided? How is Spain facing up to the challenge? Dr Juan Pablo Horcajada, Head of the Department of Infectious Diseases at Hospital del Mar, Barcelona, and spokesperson of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), assessed the situation and…

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Article • Antimicrobial stewardship

A diagnostic marker reduces antibiotics use

Since 2009, as part of diagnostic and antimicrobial stewardship strategies, Hampshire Hospitals National Health Service (NHS) Trust has used serum procalcitonin (PCT) – an innovative and highly specific marker to diagnose clinically relevant bacterial infections and sepsis. Report: Mark Nicholls

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Article • Public Health

Romania: Land of hope

Although Romania joined the EU in 2007, only recently has its macroeconomic increases influenced a rise in a middle class and dented the country’s widespread poverty. However, development is still hampered by corruption and red tape in its commercial world. Report: Daniela Zimmermann/Brenda Marsh

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News • Microscope technique

Speeding identification of deadly bacteria

A new way of rapidly identifying bacteria, which requires a slight modification to a simple microscope, may change the way doctors approach treatment for patients who develop potentially deadly infections and may also help the food industry screen against contamination with harmful pathogens, according to researchers at the Korea Advanced Institute of Science and Technology (KAIST) in Daejeon,…

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Article • Infections following joint-replacement surgeries

How to optimize prevention and therapy strategies

For all the advances being made in this discipline, postoperative infections remain a great challenge for orthopaedists and trauma surgeons. More than 7,000 experts from around the globe are gathering in Prague for the 16th EFORT Congress to consult on ways to optimise prevention and therapy for these dreaded complications.

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News • Bacterial viruses

Tools of the trade

LMU researchers demonstrate for the first time that bacteriophages (bacterial viruses) carry genetic instructions for proteins that mediate the transport of their DNA to specialized replication sites in the host cell.

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Article • Nosocomial infections I

Microbes vs. viruses

In European acute care hospitals, on any given day, an estimated 80,000 patients – roughly six percent of all patients – receive antimicrobial treatment to fight a healthcare associated infection (HAI), according to the European Centre for Disease Prevention and Control (ECDC). Report: Walter Depner

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Article • Fast, accurate and convenient

New test identifies early sepsis

A newly launched test enables the quantitative determination of PCT in serum samples, EDTA or lithium heparin plasma samples by latex enhanced immunoturbidimetric methodology. The Stanbio Chemistry Procalcitonin (PCT) LiquiColor Assay was launched by EKF Diagnostics, based in Cardiff, Wales, which explains: ‘Procalcitonin is a marker for bacterial infection and sepsis and has been recognised as…

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News • ECCMID 2015

Curetis launches next-generation pneumonia application

Curetis AG, a developer of next-level molecular diagnostic solutions, announced the successful completion of the clinical and analytical CE performance evaluation of its next-generation Unyvero P55 Pneumonia Application. The upgraded cartridge will launch at the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID, April 25 – 28, 2015 in Copenhagen, Denmark) and is…

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News • New guidance

Contact precautions for hospital visitors

Leading infectious diseases experts have released new guidance for healthcare facilities looking to establish precautions for visitors of patients with infectious diseases. The guidance looks to reduce the potential for healthcare visitors in spreading dangerous bacteria within the healthcare facility and community. The recommendations are published online in Infection Control & Hospital…

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Fighting HIV with antibodies

30 years after HIV was discovered to be the cause of the acquired immune deficiency syndrome AIDS, and despite intensive research, no vaccine or cure has yet been found. An international team of scientists, in collaboration with the German Center for Infection Research (DZIF) and the University Hospital of Cologne, has now tested a new generation of antibodies in humans for the first time. They…

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News • ECCMID

Scientists gather to fight infectious diseases

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) announces that the globe’s most prominent infection specialists will be gathering in Copenhagen to explore solutions to the biggest infection problems during its annual congress – the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) taking place on 25-28 April 2015.

News • Fighting Infection

WHO joins ESCMID to fight global infections

The European Society for Clinical Microbiology and Infectious Diseases (ESCMID) has been joined by the World Health Organisation (WHO) to launch the 7th annual ‘International Day for Fighting Infection’ (April 24th, 2015). This year’s event sees the European society exploring vaccines as a possible solution in the global, cross-border fight against antimicrobial resistance.

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