
Interview • Neurological diseases
No case for a psychiatrist’s couch
Up to ten years ago only a handful of antibodies that could be detected in the blood were known to neurology.

Up to ten years ago only a handful of antibodies that could be detected in the blood were known to neurology.

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

Neural stem cells have been found in epileptic brain tissue - outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy.

Cedars-Sinai neurosurgeons have begun using a high-definition imaging device to see inside the brain during surgery, allowing them to map safer pathways to reach and remove tumors.

Surgery will change – with all the challenges that developments such as Big Data create there are no two ways about it. However, how deep those changes run remains to be seen. In a rather young field of research, scientists look at the ways all components used during surgery can be interlinked. Professor Beat Müller, co-initiator of the project ‘Cognition-Guided Surgery’, explains results…

3-D printed tumour-like constructs will be used by a research team at Scotland’s Heriot-Watt University in Edinburgh, to raise research to a new level and successfully lead to new treatment options.

Brain cancer treatment is taking a major step ahead as Spanish surgeons pioneer a new technique that spares language and motion functions. This splendid development might even one day result in epilepsy surgery.

Stroke patients are starting a trial of a new electronic device to recover movement and control of their hand. Neuroscientists at Newcastle University have developed the device, the size of a mobile phone, which delivers a series of small electrical shocks followed by an audible click to strengthen brain and spinal connections.
“The medical rationale for stroke being a disease of the brain is overwhelming.” This is the key message of an urgent appeal launched by leading neurology experts in The Lancet.1 The authors are making public their concern about the classification of stroke in the draft revision of the “International Statistical Classification of Diseases and Related Health Problems” (ICD) after an…

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's. Now, researchers at Johns Hopkins say they have pinpointed the protein at the end of that chain of events, one that delivers the fatal strike by carving up a cell's DNA. The find, they say, potentially…

Tufts University researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain, according to a paper published in Stem Cell Reports. The work could pave the way for experiments that engineer other innervated tissues, such as the skin and…

Stroke patients will first undergo a CT scan as they enter the hospital. Before any further imaging scan is carried out, the medical team must decide whether they need to intervene intra or extra cranially. ‘Imaging enables you to see which pathology you are dealing with and helps you select patients for either recanalisation or revascularisation or, in some cases, occlusion by embolisation,’…

Joshua Bederson, MD, Professor and System Chair for the Department of Neurosurgery at Mount Sinai Health System, is the first neurosurgeon to use CaptiView – a microscope image injection system from Leica Microsystems that overlays critical virtual reality imaging directly onto the brain when viewed through the eyepiece, known as the ocular, during surgery.
INSIGHTEC announced the signing of a strategic agreement with the global leader in Magnetic Resonance Imaging, Siemens Healthineers. The strategic collaboration will involve the development of compatibility between Exablate Neuro and Siemens leading 1.5T and 3T clinical MRI systems, MAGNETOM Aera and Skyra. With this agreement, Siemens Healthineers follows its strategy of broadening and…

‘An autonomously working robot in the operating theatre will continue to be a vision of the future for a long time to come,’ according to Professor Uwe Spetzger, Clinical Director and Neurosurgery Specialist at Karlsruhe City Hospital. At the same time, he is calling for political support for the development and promotion of these innovative technologies and asking funding bodies to rethink…

Adaptation in reaching - gradual improvement of motor control in response to a perturbation - is a central issue in motor neuroscience.However, even the cortical origin of errors that drive adaptation has remained elusive. In a new paper Inoue, Uchimura and Kitazawa have shown that error signals encoded by motor cortical neurons drive adaptation in reaching.

In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects – and even controls – creatures’ social behavior, such as their desire to interact with others. So could immune system problems contribute to an inability to have normal social interactions? The…

The age of exploration has long passed, but there is at least one area still largely uncharted: the human brain. Now, a detailed new map by researchers at Washington University School of Medicine in St. Louis lays out the landscape of the cerebral cortex – the outermost layer of the brain and the dominant structure involved in sensory perception and attention, as well as distinctly human…

A European study led by Umeå University Professor Lars Nyberg, has shown that the dopamine D2 receptor is linked to the long-term episodic memory, which function often reduces with age and due to dementia. This new insight can contribute to the understanding of why some but not others are affected by memory impairment.

A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.

First the good news: the most severe Ebola outbreak ever has been contained. Last December, Guinea, where the first infection was reported in late 2013, was declared free of Ebola cases. Liberia was considered free of Ebola in mid-January after no new case had been reported for 42 days (the WHO criterion for ‘free of Ebola’).

Cooperation on Artificial Intelligence complements its initiatives on Enterprise Imaging, Big Data and Clinical Analytics, to provide an e-Health platform for Integrated Care and Population Health Management.

CarThera, a French company based at the Brain and Spine Institute (ICM), that designs and develops innovative ultrasound-based medical devices to treat brain disorders, announces the publication on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound. This has been achieved in association with teams from the Assistance Publique-Hôpitaux de Paris (the Greater…

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation – a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.

Her Majesty Queen Elizabeth II has officially opened the Cardiff University Brain Research Imaging Centre (CUBRIC), a unique neuroimaging research hub in Wales. The facility will seek to provide unprecedented insights into the causes of neurological and psychiatric conditions such as dementia, schizophrenia and multiple sclerosis, as well as an understanding into the mechanisms of a healthy…