Laboratory

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News • Microbiological big data analysis

Building a 'Microbiome Search Engine'

Big data makes big promises when it comes to providing insights into human behavior and health. The problem is how to harness the information it provides in an efficient manner. An international team of researchers has proposed a microbiome search-based method, via Microbiome Search Engine (MSE), to analyze the wealth of available health data to detect and diagnose human diseases. They published…

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News • Coronavirus disease diagnostics

Emergency Use Authorization for COVID-19 test

French in vitro diagnostics company bioMérieux announced that its subsidiary, BioFire Defense, has received Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration of its BioFire COVID-19 test for use in CLIA moderate and high complexity clinical laboratories to detect the novel coronavirus SARS-CoV-2. The test detects SARS-CoV-2 in approximately 45 minutes from a…

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News • COVID-19 status

Whole genome sequencing to map coronavirus spread

The Government and the UK’s Chief Scientific Adviser have backed the UK’s leading clinicians and scientists to map how COVID-19 spreads and behaves by using whole genome sequencing. Through a £20 million investment, the consortium will look for breakthroughs that help the UK respond to this and future pandemics, and save lives. COVID-19 Genomics UK Consortium - comprised of the NHS, Public…

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Sponsored • Endoscope drying

Empowering Reprocessing Staff: Improving Patient Safety

Human factor aspects of reprocessing can never be completely avoided yet staff can be empowered to reduce the risk of infection. This was an important conclusion established at a multidisciplinary expert panel held at Pentax Medical’s R&D Center, discussing infection risk mitigation in endoscopy. This panel of experts, consisting of physicians, nurses, microbiologists, infection control…

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News • RT-PCR for COVID-19

First of 3 diagnostic tests for SARS-CoV-2 coronavirus available

Biotechnology company bioMérieux, a world leader in the field of in vitro diagnostics, is announcing the forthcoming launch of 3 different tests to address the COVID-19 epidemic and to meet the different needs of physicians and health authorities in the fight against this emerging infectious disease. bioMérieux has finalized the development of the SARS-CoV-2 R-Gene test. This real-time PCR test…

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News • Improved grip and comfort

New cap design for capillary blood collection tubes

The MiniCollect Capillary Blood Collection System launched by Greiner Bio-One in 2016, has an improved cap on all its blood collection tubes. The new version, designed for easier opening, has an increased number of ridges that are also deeper to improve grip and user comfort. The cap rim also overlaps the top of the tube to augment grip and ease opening. The capillary blood collection tubes offer…

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News • Pandemic prevention

German lab developed coronavirus detection method

Investigators at Hannover Medical School (MHH) in Germany have developed a molecular assay for detecting the novel coronavirus SARS-CoV-2 (previously 2019-nCoV) on the automated Panther Fusion system by Hologic. The preclinical assay is described online in the Journal of Clinical Virology. “Rapid diagnosis is critical to combatting the spread of pandemics, and the Panther Fusion system is well…

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Article • Lab technician shortage

Addressing the critical lack of skilled lab workers

The UK and Europe are facing a serious lab skills shortage over the next decade with medical laboratories among the worst affected. An ageing population and skilled operators retiring without being replaced by a new generation of lab technicians is at the core of a critical lack of skilled lab workers, with it taking 5-10 years for a technician to become fully competent and an expert in their…

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Article • On the way to diagnostic mainstream

Liquid biopsy to advance cancer diagnosis

Liquid biopsy offers a new dimension to detection and stratification of cancer – yet the technique also faces hurdles in becoming a mainstream diagnostic approach for more personalised treatments. A critical challenge lies in identifying the extremely low concentrations of the bio-analytes of CTC (circulating tumour cells), ctDNA (circulating tumour DNA) and exosomes in the blood.

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News • Triple-negative forms impeded

Scientists stop breast cancer cells from spreading in the lab

Biologists have discovered a way to stop cells from one of the most aggressive types of breast cancer spreading in the lab. The study points towards new avenues of research to combat the devastating disease. The results of the study of Triple-Negative Breast Cancer by the team from the Universities of Manchester, Glasgow and Sheffield and funded by Breast Cancer Now are published in Oncogene.…

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News • Development of a highly sensitive analytical workflow

Collaboration for infectious disease diagnosis and patient monitoring

Thermo Fisher Scientific and NanoPin Technologies, Inc. have entered into a collaborative relationship to advance blood-based infectious disease detection technology through the development of highly sensitive liquid chromatography mass spectrometry (LC-MS)-based workflows. Through the detection of disease-related antigens directly from patient blood samples, NanoPin's unique diagnostic platform…

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News • Lab equipment

New high-precision digital reagent dispensers launched at SLAS 2020

Scientists working across drug metabolism and pharmacokinetics, bioanalytical, pre-clinical and clinical trial applications can now access a range of digital reagent dispensers designed to enable assay miniaturization, boost productivity and improve accuracy of results. Offering enhanced dispensing precision, the new systems use ten times less reagent compared to manual pipetting workflows,…

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Video • New virus 2019-nCoV

Scientists grow Wuhan coronavirus in the lab

Scientists from The Peter Doherty Institute for Infection and Immunity in Melbourne have successfully grown the Wuhan coronavirus (also known as SARS-CoV-2) from a patient sample, which will provide expert international laboratories with crucial information to help combat the virus. This is the first time the virus has been grown in cell culture outside of China. The Royal Melbourne Hospital’s…

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Article • Lab advances against doping

A powerful tool for sports drug testing

Due to the scientific and technical developments in recombinant DNA technology and protein engineering since the early 1980s, therapeutic proteins have emerged as one of the most important classes of new pharmaceuticals. Currently, more than 200 protein and peptide based drugs have gained approval by the USA’s Food and Drug Administration (FDA) and many more are under preclinical or clinical…

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Sponsored • Screening for the use of 5-FU anti-cancer drug

Fully-automated DPD deficiency testing

Each year almost 80,000 new patients in France alone receive fluoropyrimidines, a group of anti-cancer drugs including 5-FU which is normally administered intravenously to treat digestive, breast and head and neck cancer. However, fluoropyrimidines-based chemotherapies can cause severe toxicities (incidence at around 20%) and sometimes lethal toxicity (incidence between 0.1 and 1%) with part of…

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News • Sprue POCT

Celiac disease: faster detection through new method

Researchers from the University of Helsinki developed a novel diagnostic method for the rapid on-site measurement of antibodies from patient samples. Now they have applied this new method for the diagnostics of celiac disease, with promising results. Point-of-care (POC) testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is receiving care.…

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News • Direct-from-blood diagnostic

T2Resistance Panel receives CE mark

T2 Biosystems, Inc., a leader in the development and commercialization of medical diagnostic products, and CARB-X, a global non-profit partnership dedicated to accelerating R&D innovation to address the rising global threat of drug-resistant bacteria, announced the granting of a CE mark to the T2Resistance Panel. With the CE mark, T2 Biosystems has met the requirements of the In-Vitro…

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Sponsored • Laboratory equipment

More safety for blood banks

Ensuring the quality of blood donations is vital. Data collected during the various processes involved must be fully traceable and documented, the company Andreas Hettich GmbH emphasises. Based in Tuttlingen, Germany, the company has produced laboratory equipment for 115 years, today focusing on centrifuges and incubators and employing 420 people worldwide. Its new HettInfo II documents all steps…

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Sponsored • Laboratory worktable

See the GrossPath GP-1500 live in action!

Laboratory staff is permanently exposed to harmful formalin vapors. The GrossPath GP-1500 reduces this risk to a bare minimum as contaminated air is being extracted immediately downward and also backwards. Additionally, the tissue grossing station complies with MAC (maximum allowable concentration) values for formalin.

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Sponsored • Innovative design

Maximum power for efficient processes

Vacuum systems are the best solution for the safe disposal of biological liquids in laboratories. A coated membrane, special valves and a high gas tightness offer the safe and sustainable disposal of biological liquid waste. The latest generation of Axonlab's universal mini vacuum extraction system was developed in a development period of around 18 months. The patented product combines years of…

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News • Presented at the NCRI cancer conference

Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells, according to new research presented at the 2019 NCRI Cancer Conference. Cancer cells produce proteins called antigens that trigger the body to make antibodies against them – autoantibodies. Researchers…

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Sponsored • Product of the Month

Using safety products reduces the risk of needlestick injuries

If a health sector employee falls ill with a bloodborne illness, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with an NSI, is one of the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Don’t take the dangers posed by NSI lightly: get…

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News • MRSA & Co.

Test to detect antibiotic resistance in less than 45 minutes

Scientists from Scotland are developing a low cost, rapid diagnostic sensor test which aims to show the susceptibility of bacteria to antibiotics within 45 minutes. Laboratory testing of samples can take up to two days and the new test aims to allow doctors to be able to prescribe the correct antibiotic to a patient for an infection more quickly. In a research paper published in the journal…

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Sponsored • Lab medicine

Four perspectives on preanalytics and patient safety

BD participated in the 5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) conference on preanalytical phase in Zagreb, Croatia 22–23 March 2019. At the conference, we met Mr Steve McManus, Prof Ana-Maria Simundic, EFLM conference chair, Prof Mario Plebani and Dr Alexander von Meyer, member of the EFLM conference scientific committee. Prof Simundic and Dr von Meyer…

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