Researchers at Hospital for Special Surgery (HSS) have uncovered a potential genetic trigger of systemic autoimmune disease. The study, the culmination of more than 10 years of research, discovered virus-like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome.
First the good news: the most severe Ebola outbreak ever has been contained. Last December, Guinea, where the first infection was reported in late 2013, was declared free of Ebola cases. Liberia was considered free of Ebola in mid-January after no new case had been reported for 42 days (the WHO criterion for ‘free of Ebola’).
Hepatitis B virus (HBV) causes hepatitis B, an infectious disease that afflicts 230 million people worldwide, thereof 440 000 in Germany. Persistence of the virus in liver cells leads to progressive organ damage in the patient and contributes to a high risk of cirrhosis and liver cancer development. Providing a new paradigm to hepatitis B understanding, researchers at the German Cancer Research…
The Zika epidemic has long assumed global proportions, experts told the Congress of the European Academy of Neurology in Copenhagen. Europe needs to get prepared to deal with the relentless spread of the health threat, in particular with a view to “imported” infection. Awareness for prevention and personal protection is important, in particular with thousands of athletes and fans soon…
The President of the World Federation of Neurology (WFN) Prof Raad Shakir (London), said today that following the first confirmed Zika-related case of microcephaly on US territory, in Puerto Rico, and the ever-growing number of sexually-transmitted Zika infections in Europe, “it is increasingly obvious that the Zika epidemic has long assumed global proportions.” As the opening of the Olympics…
Virologists from KU Leuven, Belgium, have shown that an experimental antiviral drug against hepatitis C slows down the development of Zika in mice. The research team was led by Professor Johan Neyts from the Laboratory of Virology and Chemotherapy.
In recent years, we have witnessed multiple epidemics of viral diseases such as Ebola or Zika. Rapid targeted intervention is key to containment. Real-time data integration and analysis can help public health authorities to maximize efficacy of intervention strategies. Dr. Richard Neher from the Max Planck Institute for Developmental Biology, Germany and Dr. Trevor Bedford from the Fred…
As one of medicine’s largest challenges, viral infections often escape vaccines due to their natural ability to mutate rapidly and develop drug resistance easily. Many viruses, such as Zika, Ebola and dengue fever, have grown into major global health epidemics with great human and economic toll. IBM Research and Singapore’s Institute of Bioengineering, Nanotechnology (IBN) announced they have…
As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease – Leishmaniasis – from gaining a similar foothold in the Americas.
No self-respecting TV crime series is without a pathologist – but the fictitious pathologist who incessantly solves crimes has little to do with reality.
Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex.
Before his presentation at ECCMID 2016, Dr Guillaume Béraud, Infectious Disease Specialist, in the Centre Hospitalier Universitaire de Poitiers, Poitiers, France, talked to European Hospital about the results from his modelling of these three “childhood” diseases measles, mumps and rubella.
Since the recent link to severe neurological defects in infants born to mothers infected during pregnancy, Zika virus (ZIKV) has become a public health and research priority. A study reports details from the 2015 Zika outbreak in Rio de Janeiro - the first with a high proportion of cases confirmed by molecular diagnosis - and proposes changes to the current diagnostic criteria for ZIKV disease.
The Zika virus may be associated with an autoimmune disorder that attacks the brain's myelin similar to multiple sclerosis, according to a small study that is being released today and will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.
The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores risks, knowledge sharing and best practices in the fight against infectious disease – has received more than 300 late-breaker abstract submissions for its annual congress, ECCMID 2016 in Amsterdam.
Rapid testing for the Zika virus is a critical need in the recent Ebola-affected countries of Liberia, Sierra Leone and Guinea, says a Georgetown University professor, because of the recent Zika outbreak on nearby Cape Verde and the similarity in symptoms between Zika and early Ebola.
From the beginning the accusation somehow beggared belief. A ‘mild’ virus was blamed for causing hideous malformations in babies’ heads. Brazil, a country suffering its worst recession since the 1930s, as well as political upheaval, became the focus of a worldwide healthcare scare.
Many viral diseases tend to become chronic – including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently. Scientists at the University of Bonn have now identified an immune factor which is partially responsible for this. Their results give rise to hopes for new therapeutic approaches. The work, which included researchers…
Scientists have a new tool for unraveling the mysteries of how diseases such as HIV move through a population, thanks to insights into phylogenetics, the creation of an organism’s genetic tree and evolutionary relationships.
Humabs BioMed SA and the Institute for Research in Biomedicine (IRB) affiliated to the Università della Svizzera italiana announced the identification, isolation and characterization of two Ebola virus neutralizing monoclonal antibodies from the blood of a survivor of an Ebola infection.
The Zika virus, unlike other mosquito-borne viruses such as dengue, is relatively unknown and unstudied. That is set to change since Zika, now spreading through Latin America and the Caribbean, has been associated with an alarming rise in babies born in Brazil with abnormally small heads and brain defects – a condition called microcephaly.
There may be a “silver bullet” for Ebola. Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch in Galveston (UTMB) reported that they have isolated human monoclonal antibodies from Ebola survivors which can neutralize multiple species of the virus.
Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these findings, published in The American Journal of Pathology, provide unprecedented, clinically-relevant insights about how MERS progresses, they…
When the Ebola virus outbreak erupted in West Africa in 2014, children infected with the virus — particularly those under age 5 — faced overwhelming challenges. Not only was there a high death rate among young children infected with the disease, they often were isolated from their families, leaving them feeling distressed and without the intensive care they needed.
Nothing could be simpler: a drop of blood is placed on a special carrier substance; after a wait of a few minutes, the slide is placed on a device that emits polarised light thanks to an inexpensive polarisation filter. It is covered with a lid containing a second polarisation filter, which blocks the light from all materials except crystalline or materials with directional properties.
