Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.
Some six million people in the U.S. suffer from scoliosis, a sideways curvature of the spine. These include approximately 2 to 3% of adolescents who are diagnosed each year with idiopathic scoliosis, which is usually identified during puberty and progresses until skeletal maturity. One in 500 children today require treatment using spine braces and 1 in 5,000 need spinal surgery. The typical spine…
Diabetes, which now affects almost 30 million Americans, can cause serious health complications, including heart disease, blindness, kidney failure and lower-extremity amputations. A lesser-known but equally grave complication is the effect of diabetes on bone health.“Clinical trials have revealed a startling elevation in fracture risk in diabetic patients,” says Liyun Wang, associate…
Looking at measurements of the vertebrae – the series of small bones that make up the spinal column – in newborn children, investigators at Children’s Hospital Los Angeles found that differences between the sexes are present at birth. Results of the study in the August issue of the Journal of Pediatrics, suggest that this difference is evolutionary, allowing the female spine to adapt to the…
Autografts, the gold standard of bone grafts, have several limitations. As a result, new orthobiologics products are being developed for the benefit of patients as well as surgeons. Innovations in biomaterials and graft design have enabled these advanced products that mimic the natural human bone and speed up bone repair and regeneration.
Damage to the spinal cord rarely heals because the injured nerve cells fail to regenerate. The regrowth of their long nerve fibers is hindered by scar tissue and molecular processes inside the nerves. An international team of researchers led by DZNE scientists in Bonn now reports in Science that help might be on the way from an unexpected quarter: in animal studies, the cancer drug epothilone…
PBT uses a high-energy beam of particles to destroy cancer cells by more accurately targeting the affected areas and is particularly suitable for complex childhood cancers. It also increases success rates and reduces side effects, such as deafness, loss of IQ and secondary cancers.