‘All human body cells contain the same DNA, but every type of cell – for example a muscle cell compared to that of a nerve – has a different gene expression pattern’, said Dr Sonja Stadler, speaking at the 2012 congress of DGKL (German Society for Clinical Chemistry).
‘This is a dramatic demonstration that medical genomics is no longer a technology of the future – it is a technology of the here and now' Report: Mark Nicholls
The brain of mammals produces new neurons for the whole of their lives. This process, called neurogenesis, enables cognitive functions such as memory or learning, and its decrease is linked to some neuro-psychiatric pathologies and intellectual disabilities.
Olympus has released a new standalone controller for the 5 megapixel DP26 camera. Using the controller, it is possible to view samples and capture images directly on a monitor screen with no need for a dedicated computer.
Working with mice, Johns Hopkins researchers have shed light on the activity of a protein pair found in cells that form the walls of blood vessels in the brain and retina, experiments that could lead to therapeutic control of the blood-brain barrier and of blood vessel growth in the eye.
New technologies for sensing chemicals that people are exposed to and their effects in the body will help scientists work towards a complete picture of how environmental pollutants influence health in a major EU initiative being launched yesterday.
A team of scientists from Johns Hopkins and other institutions report that restoring tiny, hair-like structures to defective cells in the olfactory system of mice is enough to restore a lost sense of smell.
Research in the field is booming thanks to newly arriving methods to identify gene sequences. Scientists are interested in a wide range of issues from disease-relevant variations of human genetic information to the detection of viral genetic material that supports therapies. Several highlights of current research were presented this spring at the 9th International Symposium on Molecular…
Scientists state concern for both human and environmental health from a very commonly used antibacterial/antifungal agent. Brenda Marsh reports
Modern wars will be fought in the cyber zone, targeting an enemy's communications technology to cause critical damage; a Tel Aviv University researcher suggests to employ similar tactics in the battle against cancer.
Artel is launching the new MVS Multichannel Verification System, an objective performance assessment and optimization tool for automated liquid handlers. The MVS offers accuracy and precision information for any liquid handling device with up to 384-channels, allowing for confidence in assay data.
‘Heal the world’ sang the Berliner Rundfunk Children’s Choir and Youth Orchestra, and thus aptly began the joint 21st International Congress of Clinical Chemistry and Laboratory Medicine and the 19th IFCC-EFCC European Congress of Clinical Chemistry and Laboratory Medicine, attracting 4,418 delegates, 2,833 visitors and 1,058 exhibiting staff to Berlin in May.
Professor Bill Keevil, Director of the Environmental Healthcare Unit at University of Southampton’s School of Biological Sciences, was among the first microbiological researchers to experiment on copper’s efficiency against pathogenic and nonpathogenic strains of E. coli bacteria and demonstrate the inherent anti-microbial property of the metal.
Bacteria are highly flexible when it comes to choosing a vehicle to enter a human body. During orthopaedic surgery, they may well settle on a prosthetic joint and cause immediate or delayed infections.
It’s a war against a perceived enemy that is not – autoimmune disease like rheumatoid arthritis, lupus erythematosus or multiple sclerosis, occur when the immune system attacks normal tissue components. Characteristic of those disease patterns are autoantibodies in the blood, which the immune system produces to attack its own organism.
The birth, in France, of its first baby to be conceived by artificial insemination on top of the selection of an embryo based on its blood, has sent new flames into the hot parliamentary debate over the reform of bioethics law.
The trend towards personalised medicine implies the development of targeted cancer therapy. Tissue based examinations by pathologists play a key role in this trend. However, the relevance is still underestimated as pathologist Professor Manfred Dietel noted in his lecture at the European Forum on Oncology 2010 in Berlin, which explained what pathology already actually renders to targeted cancer…
Improvements in microfluidics and detection technologies are beginning to expand the range of point-of-care diagnostics beyond simple blood chemistry tests to sophisticated immuno-assays and molecular diagnostics. Though yet to see much adoption in European hospitals, these point-of-care (POC) diagnostics are coming into use in the USA, initially in emergency rooms and ICUs where fast results are…
The world consists of molecules – so do we. With the progression of measurement tools such as microscopes, centrifuges, or spectrometers, mankind is becoming better and better in identifying the substances from which our world is made. Today, with the technical developments in mass spectrometry, biomolecules can be weighted with the highest precision and accuracy ever known, placing it among…
For some time, German pathology has only been in the background of the medical disciplines. However, during the last ten years the profession stepped up to the fore. In the face of molecular medicine developments, the German Association of Pathologists redefined its members position with revived self-confidence.
Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, German neuroscientists have now discovered that neurons systematically recycle the protein components necessary for transmitter…
It sounds like an idea plucked from the realms of science fiction writing. But in this case, there is nothing fictional about it. Scientists in Yorkshire have developed a process that uses the luminous cells from jellyfish to diagnose cancers deep within the human body.
Cancer stem cells (CSCs) are the engine that drives tumour growth. They can not only reproduce themselves but also differentiate to form all the specialised cells found within a tumour. While chemotherapy and radiotherapy non-specifically target all rapidly dividing cells, there is increasing evidence that CSCs are more resistant to these treatments. Report: Karoline Laarmann
Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. In the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic…
Scientists from the Cancer Research UK Cambridge Research Institute and The Institute of Cancer Research (ICR) built on earlier genome-wide research to link a genetic change associated with prostate cancer risk to a significant reduction in the amount of a protein called microseminoprotein-beta (MSMB). The protein - which regulates prostate cell death - is produced by normal prostate cells –…
