Transplantations

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Heart in hand

Surgeon Alain Carpentier is ready to remove a patient’s heart and replace it with a mechanical device he spent 15 years developing. By 2013 the procedure will be performed on 50 European patients as part of a clinical trial to win CE approval for the world’s first fully implantable artificial heart.

Global Use and Availability of Treatment Involving Transplantation of Blood Stem Cells

An examination of the world-wide use of hematopoietic stem cell transplantation (HSCT), which involves transplantation of blood stem cells derived from the bone marrow or blood, finds that there are significant differences in transplant rates between countries and continental regions by indication and donor type, and that HSCT is most frequently used in countries with higher gross national…

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Liver stiffness measurements identify patients with rapid or slow fibrosis

A recent study determined that repeated liver stiffness measurements (LSM) in the first year following liver transplant (LT) could discriminate between slow and rapid "fibrosers". LSM were extremely accurate, particularly at the 6-month post LT point, in detecting severity of fibrosis. Determining those at risk for a recurrence of hepatitis C virus (HCV) allows for early-stage administration of…

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Revolutionary approach to heart failure

British girl Hannah Clark who was given an extra heart as a toddler has become the world's first heart transplant patient to make a full recovery after having her donor organ removed and function restored to her original heart. The case highlights that in some cases of cardiomyopathy, it is possible for the patient's own heart to make a full recovery if it is given adequate support to do so.

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The state of play in EU States

Waiting lists for organ transplants are lengthening in most European countries, forcing the need to increase donations higher up the medical and political agenda, Mark Nicholls reports. Spain continues to lead the way in organ donation with the so-called Spanish Model approach, while other countries, e.g. the UK, are debating whether to adopt 'presumed consent' and an 'opt-out' rather than…

The impact on soma and psyche

There is a profound difference between the complexity of cosmetic surgery or organ transplant procedures, for example, and other operations. Whilst procedures such as hair transplants or eyelid surgery present an alteration to the owner's body composition and changes to the patient's outlook, those changes were desired and planned for, in the hope that something marvellous will result and so…

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When donors are not forthcoming

Expectations ran high when the German Transplant Law (TPG) was introduced in 1997. The government felt it had done its part to ensure more legal certainty for the donation, removal and transplantation of organs: the population could feel encouraged to sign up for organ donation and was supposed to follow suit. However, this did not occur.

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Lifebridge B2T

Worldwide interest in portable systems for cardiopulmonary support has grown significantly. While some systems are at the brink of market introduction, German company Lifebridge Medizintechnik AG reports that it is 'at the top of this medical technology market', for its smallest, lightest (18kg) system, Lifebridge B2T ('Bridge to Therapy') has been in clinical use since the beginning of 2008.…

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Insulin-Produktion dank transplantierter Zellen

Die erste am Universitätsklinikum Carl Gustav Carus vorgenommene Transplantation von Inselzellen aus einer Bauchspeicheldrüse verlief erfolgreich: Zwei Wochen nach dem Eingriff bildet die seit 51 Jahren an Diabetes Typ 1 erkrankte Patientin wieder körpereigenes Insulin. Die Transplantation ist Ergebnis einer über zwei Jahre dauernden, aufwendigen Aufbauarbeit an Uniklinikum und Medizinischer…

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Stop transplanted insulin cells from dying

Researchers at Linköping University and Uppsala University in Sweden can show that accumulation of protein aggregatess, amyloid, in the transplanted cells may be causing their death. With the aid of their results, physicians can enhance survival of islets transplants and improve treatment of type 1 diabetes.

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