The biotech industry is being hit twice as hard by the economic crisis. In addition to the general economic downturn, the largely dried-up equity market, which has massively complicated the usual equity financing through the stock exchange or venture capital, is causing problems for companies.
Talking about medical innovations, new drugs, techniques and technologies are the first things that come to mind, whereas new indications for existing pharmaceuticals, especially biological medicines, play a minor role.
The threat of communicable diseases will become even worse in the near future. At the European Health Forum Gastein, the European Union's leading health policy congress for experts and decision-makers, experts stressed that there are a number of risk factors which contribute to a growing risk of the spread of communicable diseases into Europe, namely into the European Union.
Colorectal cancer (CRC) jointly describes cancers of the colon and rectum. Worldwide, CRCs are among the most common cancers. In Europe and the USA the occurrence of CRCs are considerably higher than in Africa and Asia.
The Leapfrog Group is a U.S. organisation of member companies that pay for healthcare services, e.g. corporations, health insurers and local, state and federal government agencies. Established in 2000, its philosophy is that big 'leaps' in healthcare safety, quality and value to patients will be recognised and rewarded. The organisation mobilises purchasing power of its members, representing over…
Positive CB7630 (Abiraterone Acetate) Phase II Data was presented at the ASCO Annual Meeting in Chicago this May/June, Cougar Biotechnology Inc, a development stage biopharmaceutical firm with a specific focus on oncology. In mid-July, Johnson & Johnson announced its acquisition of Cougar, which is now working with Ortho Biotech Oncology Research & Development, a division of the J&J firm Centocor…
The fact that child diabetics (type I) in Russia do not receive necessary and qualitative therapy was again highlighted during the 7th Russian conference 'The priority national project - Health - and the tasks of children's endocrinologists' held in Saint-Petersburg this June.
Completion of a Phase I clinical trial has demonstrated the great promise of a completely new type of cancer treatment, according to results announced this June in The New England Journal of Medicine by scientists at the Institute of Cancer Research (ICR) and the Royal Marsden Hospital in the United Kingdom, working with pharma firm AstraZeneca.
In the genetic material of cancer cells, important growth inhibitors are often switched off by chemical labels in the DNA. Scientists of the German Cancer Research Center and the Ohio State University, USA, discovered in mice that cancer-typical DNA labeling occurs long before the first symptoms of leukemia appear. A test for the genetic label might therefore help to detect a developing cancer at…
Bayer Schering Pharma AG, Germany, has presented positive data on a global Phase II study with the novel positron emission tomography (PET) tracer florbetaben (BAY 94-9172) at the International Conference on Alzheimer's Disease (ICAD) in Vienna, Austria. This study showed that patients with a clinical diagnosis of Alzheimer´s disease could be differentiated from age-matched healthy volunteers…
Forensic toxicology is the post-mortem testing for lethal and/or foreign substances in body fluids and tissues, and it can be a very time-consuming process. The media has reported that Michael Jackson's death certificate was issued on Tuesday, July 7, 2009 without listing a cause of death; his brain, or part of it, was being retained for testing; and initial indications are that it may take…
Newly designed centerpieces used in the Beckman Coulter XL-A and XL-I instruments - the only analytical ultracentrifuges on the market today - allow the systems to provide precise, repeatable measurement of pharmaceutical sample aggregation in pharmaceutical research and formulation laboratories.
The inflammatory process in the brain of multiple sclerosis patients is triggered by their own immune system. However, there is one type of immune cells that seems to fight against the destructive progress - and might be used for therapeutic purposes in future.
The first strain of methicillin resistant Staphylococcus Aureus (MRSA) was isolated in the 1960s, and its presence was reported worldwide in the late 1990s. A higher incidence of MRSA was noted in communities, at the dawn of the new millennium, leading to two basic MRSA strains being differentiated - CA-MRSA (community acquired MRSA) and HA-MRSA (healthcare associated MRSA). In clinical practice…
According to ECD statistics for Europe, three million cases of nosocomial infections occur annually, and 50,000 are fatal. Evelina Tacconelli MD PhD (below) is Assistant Professor of Infectious Diseases at the Università Cattolica Sacro Cuore in Rome, Italy. Her scientific focus is on epidemiology, clinical and therapeutic aspects of nosocomial infections and infection control policies aimed to…
European hospitals are increasingly using robotic dispensing systems to accelerate drug distribution and the patients discharge process.
During the race to produce vaccines against evolving influenza viruses the slowness of their manufacture has turned producers more sharply towards cell culture technology. Using the traditional process, fertilised chicken eggs must first be inoculated with live flu virus, then the resulting egg-adapted virus must be purified and inactivated to produce trivalent inactivated virus (TIV), during…
Beckman Coulter, Inc. has expanded its drugs of abuse test menu to include a DRI* Oxycodone Enzyme Immunoassay (OXYX). The assay is for the qualitative and semi-quantitative determination of oxycodone and its metabolite, oxymorphone, in human urine.
Fifteen new research projects aimed at bringing innovative medicines to market faster have been selected to receive 246 million Euros from the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The projects will foster understanding of health issues such as diabetes, pain, severe asthma and psychiatric disorders while increasing medicine safety.
Today help is often available for those suffering from high blood pressure in the pulmonary circulation (pulmonary arterial hypertension/PAH). New drugs — so-called endothelin receptor antagonists — make it possible to alleviate the symptoms, improving patients' physical strength and quality of life.
As processes become more complex, the need for increased laboratory safety is paramount. Protecting operators from hazardous substances, aerosol release or spillages is a critical consideration during processes, whether they are mixing substances or dispensing drugs. Of equal importance is the need to protect the substance, or product, from contamination from the operator. Mark Nicholls presents…
The last time medical science enriched clinical practice with new advanced technologies ideas about aetiology and the treatment principles of a great number of diseases changed. Now the dilemma of modification of diagnoses and treatments, including laboratory diagnostics, is a very hot issue in Russia.
Among 2,552 European R&D projects (clinical phases I-III) conducted by small and mid-size biotechnology firms (under 600 employees), 64 are focused on diabetes, according to a large, detailed study carried out by Novumed Life Science Consulting.
An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area.
In a symposium organised by Bayer Schering Pharma at the 2009 European Congress of Radiology (ECR), the audience heard a series of four presentations on the potential advantages of high-signal-intensity contrast agents for MRI, focusing on gadobutrol (Gadovist). During the discussion, several claims made by the speakers were challenged and debated by ECR delegates.