By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new mechanism of chronic migraine, and propose a cellular pathway for migraine therapies. The study, “Neuronal…
Osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to the joint disease and have identified a commonly used anti-depressant — paroxetine — that inhibits this pathway.
There is currently no cure for osteoarthritis, but a group of scientists believe they’ve discovered a method through which a simple knee injection could potentially stop the disease’s effects. These researchers showed that they could target a specific protein pathway in mice, put it into overdrive and halt cartilage degeneration over time. Building on that finding, they were able to show that…
A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the RSNA.
Females process pain differently, but search for pain medication still based on hypotheses drawn from work in males, a study from Canada finds. It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular, cellular, and physiological levels. Despite this fact,…
Pain researchers around the world have agreed to classify pain in the mouth, jaw and face according to the same system; according to a Danish participant, this means more precise diagnoses and improved treatment.
One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent study, a team at the Technical University of Munich (TUM) discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the…
Researchers at Karolinska Institutet in Sweden have discovered a new sensory receptor organ that is able to detect painful mechanical damage, such as pricks and impacts. The discovery is being published in the scientific journal Science. Pain causes suffering and results in substantial costs for society. Almost one person in every five experiences constant pain and there is a considerable need to…
Researchers at Washington University School of Medicine in St. Louis have found, in mice, that treatment with an antibiotic reduces the size of lesions caused by endometriosis. The researchers are planning a large, multicenter clinical trial to test the drug metronidazole in women who have the painful condition. The study is published online April 30 in the journal Human Reproduction.…
For the first time ever, chronic pain will be classified as a diagnosis in line with other diseases when the World Health Organization (WHO) approves the next catalogue of recognised diseases in May. According to Professor Peter Svensson from the Department of Dentistry and Oral Health, this is very significant for the approx. 20% of the population who suffer from chronic pain. Working with top…
Specialists are seeing more and more repetitive stress injuries (RSI) from overuse of smartphones and tablets – the main instigators of emerging conditions like texting thumb and selfie elbow, notes UT Southwestern rehabilitation specialist Dr. Renee Enriquez. “With all overuse injuries, rest is the most important part of recovery. Complete rest is best, but since technology is a required…
Innovative virtual reality (VR) technologies hold promise in reducing children’s anxiety and pain before and after medical procedures and surgery, suggest two studies that were presented at the Anesthesiology 2018 annual meeting. The first study found virtual reality hypnosis (VRH) reduced anxiety, total postoperative opioid consumption and vomiting in children after scoliosis surgery.…
Four potentially game changing solutions selected for the annual commercial acceleration program of the Spanish foundation for innovation and prospective in healthcare (Spanish: FIPSE), included Duralock, a system that could ease post partum pain by avoiding postdural puncture headache (PDPH), a common complication of epidural anaesthesia. PDPH occurs when the anaesthesiologist punctures the dura…
Early detection of mesenteric ischemia increases treatment options and the possibility of a full recovery, but the condition’s rarity may lead to a delay in diagnosis while more common causes of abdominal pain are explored. An article in the February 2018 issue of Critical Care Nurse (CCN) aims to heighten nurses’ knowledge of mesenteric ischemia and infarction (MI), which are infrequent but…
Patients significantly overestimate the anticipated amount of pain they’ll experience following surgery, which researchers say can cause unnecessary anxiety in patients, according to a new study. Patients who receive regional anesthesia, such as peripheral nerve blocks, epidurals or spinal anesthesia, were most likely to overestimate their postoperative pain.
In a review of half a dozen published studies in which patients self-reported use of opioids prescribed to them after surgery, researchers at Johns Hopkins report that a substantial majority of patients used only some or none of the pills, and more than 90 percent failed to dispose of the leftovers in recommended ways.
In a small study of opioid prescriptions filled at a Johns Hopkins Medicine outpatient pharmacy, researchers found that handwritten orders for the drugs contribute heavily to a trio of prescribing and processing errors in contrast to those created electronically.
For people with headache, seeing the neurologist by video for treatment may be as effective as an in-person visit, according to a study published in the June 14, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.
Just ten minutes of mindfulness meditation could be used as an alternative to painkillers, according to research by Leeds Beckett University.
Currently available pain medications have limited efficacy and numerous side effects. New research, however, provides deeper insights into how our bodies process pain, paving the way for an innovative, more effective way of targeting chronic pain.
New state-of-the-art technology helps clinicians provide personalised pain relief
Have you seen the videos? Perhaps you have read the 20-page paper published in Radiology? At MR 2017 Garmisch you will have the chance to see and hear a live presentation by William Palmer, M.D., Director of Musculoskeletal Radiology & Intervention at Massachusetts General Hospital, a teaching hospital of the Harvard Medical School.
Despite messages to the contrary, most women being seen by a doctor for the first time with suspected heart disease actually experience the same classic symptoms as men, notably chest pain and shortness of breath, according to a study led by the Duke Clinical Research Institute.
For most people, the culmination of a good life is a “good death,” though what that means exactly is a matter of considerable consternation. Researchers at the University of California, San Diego School of Medicine surveyed published, English-language, peer-reviewed reports of qualitative and quantitative studies defining a “good death,” ultimately identifying 11 core themes associated…
Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!" The pain is real and it serves a purpose, otherwise we'd suffer greater injury. But for many people with chronic pain, that signal keeps getting sent for months or years, even when there is no…