Search for: "ipsc" - 11 articles found

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News • Bioengineering

Producing transplantable livers in the laboratory

Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory. The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of…

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News • Tiny changes, huge effects

Finding causes of disease with induced pluripotent stem cells

Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex and also rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL), together with international partners, have studied genotype-phenotype relationships in iPSCs using data from approximately one thousand donors. Tens of…

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News • iPSC research

'Brain cell grafts' hold promise for reversing Parkinson’s symptoms

Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison report. In a study published in the journal Nature Medicine, the team describes its success with neurons made from induced pluripotent stem cells from the monkeys’ own bodies.…

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News • Immune response regulation

Using iPS cells to fight transplant rejection

Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues. The team, led by Professor Ken-ichiro Seino of Hokkaido University’s Institute for Genetic Medicine, found that thymic epithelium cells derived from mouse induced pluripotent stem cells (iPSCs) can regulate immune response to skin grafts, extending their…

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News • Induced pluripotent stem (iPS)

Researchers find way to generate stem cells more efficiently

Induced pluripotent stem (iPS) cells are among the most important tools in modern biomedical research, leading to new and promising possibilities in precision medicine. To create them requires transforming a cell of one type, such as skin, into something of a blank slate, so it has the potential to become virtually any other kind of cell in the body, useful for regenerative therapies for…

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News • Bioengineering

Squeezing cells into stem cells

École polytechnique fédérale de Lausanne (EPFL) scientists have developed a new method that turns cells into stem cells by "squeezing" them. The method paves the way for large-scale production of stem cells for medical purposes.

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The German Stem Cell Network

More than 400 international scientists headed for the Max Delbrück Centre in Buch, near Berlin for updates on stem cell biology findings and discuss how to develop synergies between basic research, regenerative medicine and pharmacology, as well as strategies to cope better with researchers’ needs. The three-day event was the first annual conference of the German Stem Cell Network founded at…

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