An overactive defense response may lead to increased blood clotting, disease severity, and death from COVID-19. A phenomenon called NETosi is part of an immune response that becomes increasingly hyperactive in people on ventilators and people who die from the disease.
When infected by the new coronavirus, women may mount a more potent adaptive immune response than do men, a new study suggests. By comparison, the male immune response appears to progress less effectively, fostering inflammation that’s harmful to the body. This study is the first to delve into sex differences in how the immune system defends itself against the virus SARS-CoV-2. It could help…
Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.
In the hustle and bustle of a hospital, properly disinfecting all surfaces in a patient room can be a challenging and time-consuming task. Now, in times of the coronavirus pandemic, it can also be life-threatening. To minimize the risk for their staff, hospitals are utilizing disinfection robots to sanitize surfaces and rooms.
Light microscope for viewing microorganisms such as bacteria and fungi are commonly found in scientific laboratories. A research team from Furtwangen University, the University of Tübingen and Carl Zeiss Vision International GmbH, Aalen, examined more closely their role as potential vectors of infectious pathogens. „Very little was known about this until now," explains the head of the…
The prevalence of ‘silent’ symptomless COVID-19 infection may be much higher than thought, reveals a study charting the enforced isolation of cruise ship passengers during the current pandemic, and published online in the journal Thorax. More than eight out of 10 of passengers and crew who tested positive for the infection had no symptoms. This has implications for the easing of lockdown…
Roswell Biotechnologies, Inc., a manufacturer of molecular electronics sensor chips, and imec, a research and innovation hub in nanoelectronics and digital technologies, announced a partnership to develop the first commercially available molecular electronics biosensor chips. These chips are the brains behind Roswell Technologies' new platform for DNA sequencing, to support precision medicine,…
COVID-19 has infected millions and killed hundreds of thousands of people worldwide, but a new predictor model devised at the Queensland University of Technology (QUT) offers glimmers of hope, suggesting the worst has passed and indicating well under 1000 deaths for Australia. The team at QUT, led by physician, mathematician and Future Fellow Dan Nicolau, has developed what they believe to be a…
Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published in the Journal of Biological Chemistry.
Researchers from Cambridge, UK, and Germany have reconstructed the early “evolutionary paths” of COVID-19 in humans – as infection spread from Wuhan out to Europe and North America – using genetic network techniques.
The number of cases tested positive for COVID-19 initially grew exponentially in China, but then slowed down. Dirk Brockmann, professor at Humboldt-Universität zu Berlin (HU) and project group leader at the Robert Koch-Institut (RKI), and his postdoc Benjamin F. Maier have developed a diffusion model that takes into account the effect of social distancing and other measures to explain this…
China's control measures during the first 50 days of the COVID-19 epidemic may have delayed the spread of the virus to cities outside of Wuhan by several days and, by interrupting transmission nationwide, prevented more than 700,000 infections across the country, according to an international team of researchers.
The sense of fear is palpable in the images and videos of hospital intensive care units (ICUs) and emergency departments that are broadcast on television and posted on social media. Fear and heartbreak can be heard in the voices of physicians and nurses who describe what they are experiencing.
In a new study, researchers found that half of the patients they treated for mild COVID-19 infection still had coronavirus for up to eight days after symptoms disappeared. The research letter was published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
A ‘pandemic drone’ to remotely monitor and detect people with infectious respiratory conditions is being developed by the University of South Australia (UniSA) in partnership with a Canadian company. The drone will be fitted with a specialised sensor and computer vision system that can monitor temperature, heart and respiratory rates, as well as detect people sneezing and coughing in crowds,…
Mathematical models can help shed light on the evolution of the coronavirus pandemic, according to Spanish mathematician Juan Luis Fernández Martínez, who predicted Spain could have between 90,000 and 160,000 infected patients. The next trend in epidemic data science will be to issue prediction models that focus on early detection.
The sunny Sunday of March 22, 2020, may well go down as a watershed date in the context of Coronavirus in the UK. A couple of days earlier, UK schools had closed en masse – open only thereafter for children of key workers – and the British government had advised that pubs, bars, cinemas, gyms and restaurants should close and people should adhere more rigorously to social distancing.
To provide reliable information about the coronavirus disease COVID-19, Professor Giuseppe Lippi, Director of the Laboratory for Clinical Chemistry and Hematology at the University Hospital of Verona, Italy, gives an overview on the current state of scientific knowledge on COVID-19 and the SARS-CoV-2 virus. The video was provided by the American Association for Clinical Chemistry (AACC), who…
The first case of the new coronavirus infection was reported on the 24th January. The strategy taken by the French to stem the spread of the virus and relieve the pressure on the health service may seem draconian to some, but many feel that it is either not strong enough and/or too long in coming because it is only recently that the borders have finally been closed.
The World Health Organization (WHO) has officially categorized the current outbreak of the novel coronavirus disease (COVID-19) as a pandemic. Speaking at the COVID-19 media briefing, the WHO Director-General Dr Tedros Adhanom said: "WHO has been assessing this outbreak around the clock and we are deeply concerned both by the alarming levels of spread and severity, and by the alarming levels…
A coronavirus app coupled with machine intelligence will soon enable an individual to get an at-home risk assessment based on how they feel and where they’ve been in about a minute, and direct those deemed at risk to the nearest definitive testing facility, investigators say. It will also help provide local and public health officials with real time information on emerging demographics of those…
The 2020 edition of the European Congress of Radiology (ECR) in Vienna, which had been postponed due to safety concerns regarding COVID-19, will not take place on site this year. Instead, the congress organisers at the European Society of Radiology (ESR) opt for an online-only event: "It is with a heavy heart and much regret that the Board of Directors of the European Society of Radiology…
In a joint effort, the U.S. Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) take action to make more respirators, including certain N95s, available to health care personnel. Currently, the majority of respirators on the market are indicated for use in industrial settings. This action allows certain National Institute for Occupational Safety and Health…
In a study of more than 1,000 patients published in Radiology, chest CT outperformed lab testing in the diagnosis of 2019 novel coronavirus disease (COVID-19). Researchers at Tongji Hospital in Wuhan, China, concluded that CT should be used as the primary screening tool for COVID-19. In the absence of specific therapeutic drugs or vaccines for COVID-19, it is essential to detect the disease at an…
A University of British Columbia (UBC) researcher is part of an international team working with a biotechnology company on a pilot clinical trial of a potential new treatment for patients with severe coronavirus infections in China. Dr. Josef Penninger, director of UBC’s Life Sciences Institute and Canada 150 Chair in Functional Genetics, is working closely with Vienna-based Apeiron Biologics…