
Contrast agents in Sonography
Ultrasound contrast agents (USCA) or echo enhancers consist of minute gas containing microbubbles that have a high reflectivity when exposed to an ultrasound field. The history of USCA started in the mid of the 1960s. The cardiologist Joyner performed echo cardiography during the injection of saline solution into the aortic root via a catheter. During the injection he observed bright signals on…