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Microchip separates and extracts tumour cells in the blood

Ikerlan-IK4 and Mondragón Unibertsitatea are taking part in a project initiated by the Spanish National Research Council, CSIC, and which has developed a microchip capable of separating and extracting tumour cells in the blood stream by means of ultrasonic waves. The Foundation General Hospital of the University of Elche, together with researcher Alfredo Carrato, has also collaborated on this…

Cancer screening made simple

Current cervical cancer screening is time consuming and expensive, but now new breakthrough technology developed by European researchers should allow large-range screening by non-medical personnel with almost immediate results and at a much lower cost.

Standardised algorithms and protocols for diabetic in-patients

Dr Susan S Braithwaite, a visiting clinical professor in endocrinology at the Department of Medicine, University of Illinois, Chicago, specialises in the management of hyperglycaemia among hospitalised patients. Hyperglycaemia, the presence of an abnormally high concentration of glucose in the blood, is a common occurrence in adults who are hospital in-patients, especially among diabetic…

Deadly disease, dismal summary

Recently, the prevalence of diabetes mellitus in the Czech Republic reached 7-8% (783,321 diabetics were treated last year – 419,362 females and 363,959 males) but this figure leaps to 25-30% for diabetes related hospitalisations.

Concern over insulin drug withdrawal

Drug company Novo Nordisk’s decision to pull its Mixtard 30 insulin drug from the UK could add almost €11 million to the NHS drugs bill in England alone, according to an editorial in the Drug and Therapeutics Bulletin (DTB). This decision could also leave thousands of patients dependent on others to help them take their insulin, said DTB, as it launched its Don’t Drop Mixtard 30 campaign in…

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Cervical cancer

Data from the ATHENA (Addressing THE Need for Advanced HPV Diagnostics) USA registration trial, involving more than 47,000 women, demonstrate that two human papilloma virus genotypes, HPV 16 and HPV 18, can identify those women with cervical pre-cancer missed by cytologic examination with a Papanicolau (Pap) test.

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The impact of diagnostic IT

At a meeting hosted by Siemens at AACC 2010, an expert panel shared perspectives on IT in the clinical lab. Representatives from Henry Ford Hospital (Detroit, MI), Alegent Health (Omaha, NE) and Johns Hopkins Bayview Medical Centre (Baltimore, MD) spoke about the increasing importance of IT in helping today’s lab to meet the challenges of cost containment, quality of care, increasing workload,…

AACC 2010

California, USA: 20,000 visitors and 700 manufacturers showing products in almost 2000 booths at the American Association for Clinical Chemistry (AACC) annual meeting (July 5-29, 2010) underlined the importance of this, the world’s largest gathering of clinical laboratory professionals.

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Cheap and fast cancer diagnosis

t the Engineering in Medicine and Biology Conference (EMBC) in Buenos Aires (Argentina), imec and its project partners announce the launch of the European Seventh Framework Project MIRACLE. The MIRACLE project aims at developing an operational lab-on-chip for the isolation and detection of circulating and disseminated tumor cells (CTCs and DTCs) in blood. The new lab-on-chip is an essential step…

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Cardiac Biomarkers

When in 1992 Dr Luigi Marzio Biasucci, head of the Sub-intensive Care Unit at the Catholic University of the Sacred Heart in Rome, Italy, published with his team the first paper on C-reactive protein (CRP) in unstable angina, few people believed in the diagnostic power of biochemical features to measure the effects or progress of disease, illness, or a condition. Today, biomarker tests are part…

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International congress to present news in dermatology

For the first time ever, the Nordic country of Sweden will host Europe’s largest dermatology meeting, the 19th Congress of the European Academy of Dermatology and Venereology (EADV), to take place in Gothenburg from 6-10 October, 2010. About 8,000 dermatology specialists - physicians, researchers, and scientists – from all around the globe are expected to participate in the meeting.

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A journey towards full automation

St Jude Medical Center, in Fullerton, California, has always taken pride in its reputation as one of Southern California’s most respected and technologically advanced hospitals. With 384 licensed beds and over 700 physicians the centre offers a comprehensive array of services and programmes, including cardiac, stroke care, a breast and cancer centres, full maternity services, orthopaedic…

Ultraviolet light - an invisible weapon against MRSA

A few years ago, Dr Peder Bo Nielsen MD FRCPath, Consultant medical microbiologist at Northwick Park Hospital, London, UK, launched a research programme on airborne transmission of nosocomial infections. Until then, so called air-biology held no high priority in infection prevention and control. The prevailing perception was that colonisation and contamination mainly happens due to direct contact…

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Tailoring cancer treatment with biomarkers

New biomarkers play a key role in individualised tumour therapy. They are important indicators for pathological processes in the body and for the use of adequate cancer drugs. In our European Hospital interview Professor Celso A Reis, from the Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP*) in Portugal, discussed the current state of clinical use of…

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Postprandial blood glucose

The daily management of diabetes mellitus is a complex interaction between blood glucose measuring, lifestyle aspects and drug therapy. Large epidemiological trials such as UKPDS (United Kingdom Diabetes Prospective Study) have shown that an optimal blood glucose adjustment has beneficial long-term effects on type-2 diabetics’ risk of micro- and macrovascular secondary complications.

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Achieving HbA1c target values

An adequate blood glucose level (4–7 mmol/l) is important not only for a diabetic’s daily well-being but also to prevent diabetes-related illnesses. HbA1c is the central marker to evaluate the success of diabetes management. But HbA1c measurement has a crucial limitation: current blood glucose fluctuations are not taken into consideration. However, the recognition of steep post-prandial blood…

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Diabetes management in the hospital

Diabetes mellitus is a lingering disease – for a long time it causes subjectively few complaints or no complaints at all. Despite this, it is life-threatening – especially if undiagnosed, or diagnosed too late. However, although diabetes is the most widespread disease it is often only discovered by accident in a hospital, where many hospital doctors feel that diabetology is the responsibility…

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The UK’s one million undiagnosed diabetics

At the end of June a shocking new estimate was released in the UK regarding the number of people unwittingly going about their lives without knowing they are type 2 diabetics – there are just over a million of them. How will the country cope with this discovery and its present diabetic population?

Patient monitoring devices

In 2009, the continuous glucose monitoring (CGM) market earned manufacturers $23.5; this is forecast to reach $52.0 million in 2016, according to a new analysis from Frost and Sullivan (F&S). For the study the markets covered by region are Benelux, Germany, France, Italy, Scandinavia, Spain and the United Kingdom.

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