Obstetrics

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First Czech "test-tube" baby celebrated 25th birthday

The first Czech test-tube baby was born, woman in childbed delivered smoothly on 4th November 1982, and healthy baby-boy was 51 cm tall, and weighed 3.65 kg. A medical team from Moravian town of Brno led by embryologist Milan Dvorak and gynecologist Ladislav Pilka was behind all this happy-ended artificial fertilization quarter a century ago.

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Pulse oximetry - screening tool in newborn babies

A research carried out at six hospitals in the West Midlands, UK, is evaluating the use of pulse oximetry as a screening tool for congenital heart disease in newborn babies. Approximately three percent of infant deaths are caused by these significant heart defects and at the moment only less than half of the affected babies are identified by clinical examination, the current screening technique.

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Close to baby

Every young mother wants to be as close as possible to her newborn baby. The "Leipiziger Wanne", the "Leipzig tub", developed by German engineering company NEL, can fulfil this wish even more easily: The c-shaped bed consists of a transparent tub which can be moved across the mother's bed allowing her eye contact with the baby at any time.

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Sonographic Indications of Fetal Chromosome Abnormalities

"Genetic ultrasound" is a refined technique in prenatal diagnostics. It aims to estimate as accurately as possible and non-invasively, the individual risk of a fetal chromosome abnormality. In conventional prenatal sonography (malformation screening) conspicuous fetal malformations are searched for selectively; naturally chromosomal anomalies of the fetus cannot be detected in this…

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From head to toe

Without doubt, the B-mode imaging is the most important examination method in prenatal ultrasound. Well over 90% of detectable congenital anomalies can be recognised using the two-dimensional realtime imaging method. Hence, paramount importance is certainly ascribed to the quality of the B-mode image in an ultrasound system. In addition, other ultrasound modalities help us to considerably enhance…

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Looking at a New Generation

Most babies are born healthy, but there is still a small risk for all women to give birth to a baby with some type of anomaly. Ultrasound has proven to be one of the most reliable procedures to prenatally diagnose some of these conditions. Ultrasound can be used during the entire pregnancy, but in the first trimester ultrasound examinations are, as a rule, used to exactly calculate the pregnancy,…

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Screening for Chromosomal Defects

Chromosomal abnormalities are major causes of perinatal death and childhood handicap. Consequently, the detection of chromosomal disorders constitutes the most frequent indication for invasive prenatal diagnosis. However, invasive testing, by amniocentesis, chorionicvillus sampling (CVS) or cordocentesis, is associated with a risk of miscarriage of about 1% and therefore these tests are carried…

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The Non-Surgical Closure of Congenital Heart Defects

What is an “open foramen ovale”? The open foramen ovale medical abbreviation PFO for “patent foramen ovale”) is a usually small, only a few millimeter thick, membrane-covered slit in the septum between the atria of the heart. It is a remnant from human embryonic development that usually closes during the newborn period; however, in 10-25% of newborns a small opening remains that generally…

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3D Vascular Imaging

Imaging of blood flow with colour Doppler sonography is an established method in prenatal medicine. Today, there are several techniques which offer colour visualisation whose quality is on a par with that of the B-mode. One example of such a technique is Advanced Dynamic Flow (ADF). Looking at two cases, we will describe the clinical use of ADF to visualise fetal vascular tumours. The quality of…

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Vascular Imaging in Prenatal Medicine

The following two articles look at the advantages of a new ultrasound technique in prenatal diagnostics: Advanced Dynamic Flow (ADF). While the authors use ADF for different purposes - K. S. Heling applies ADF for general vascular imaging and R. Schmitz focuses on fetal liver tumours and a fetal aneurysm in the vein of Galen - they both arrive at remarkably similar conclusions. But read for…

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Tissue Doppler Imaging of the Fetal Heart

In the last 25 years, fetal echocardiography has become established as an integral component of prenatal medicine. Structural heart defects are found in approx. 0.8% of all foetuses. They are consequently comparatively frequent and head the list of isolated fetal organ malformations. Routine screening of the four-chamber view and the outflow tract allows the experienced investigator to detect…

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