PET and recurrent cancer

More sensitive dissemination tests are needed for patients with locoregionally recurrent (LRR) breast cancer, according to a paper by Dutch researchers published online by the European Journal of Cancer (Volume 40, Issue 10 , 7/2004).

The study aimed to describe the extent and yield of daily clinical practice when staging LRR breast cancer patients and to explore prospects for positron emission tomography (PET). Using the population-based Eindhoven Cancer Registry to select all breast cancer patients in the country’s southeast, with a first episode of LRR between 1/1/1994 and 30/6/2000, it was found that, on LRR presentation, 16% of the 175 patients had distant metastases and a further 24% were diagnosed with distant metastases within 18 months.

Additional data concerning staging procedures and follow-up were collected from medical records, and 77 physicians were also approached with a questionnaire seeking their opinions on staging procedures and actual treatment policy. Of the 75% of physicians who responded to the questionnaire, 33% thought the sensitivity of conventional imaging techniques was too low. The study team said it tended to conclude that ‘...in daily clinical practice there is a need for more sensitive dissemination tests for patients with a LRR of breast cancer.’

01.07.2004

Read all latest stories

Related articles

Photo

News • New imaging agent

HER2-positive breast cancer: Whole-body PET/CT predicts targeted therapy response

A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.

Photo

Article •

Still a lot to learn about breast cancer

Since decades women carefully feel their breast. Hoping that they will not find any evidence for lumps or other changes, that might signal breast cancer. However, a review of recent studies conclude…

Photo

News • Breast cancer

Double mastectomy slashes risk - but not for all women

Healthy women who carry a breast cancer-causing mutation in the BRCA1 gene, not only reduce their risk of developing the disease but also their chances of dying from it if they have both breasts…

Related products

Subscribe to Newsletter