Lumpectomy is not advised if breast cancer returns

A mastectomy is prudent when breast cancer returns after a lumpectomy, because survival rates are higher for those who have another lumpectomy, according to a new study published in the American Journal of Surgery in October.

‘We were surprised to find that so many women in our study – almost a quarter – had received another lumpectomy rather than a mastectomy,’ said Dr Steven L Chen, from the University of California Davis Cancer Centre in Sacramento. ‘It’s likely that patients are asking for lumpectomies when their cancer is diagnosed a second time, and their doctors are simply complying with that request. Whatever the reason, that decision can shorten life spans.’
The study involved 747 women who had a same-breast cancer recurrence after undergoing breast conservation therapy. Of these patients 24% underwent a second lumpectomy. The five-year survival rate was 67% for women who had a lumpectomy compared with 78% for those who had mastectomies. Analysis confirmed that lumpectomy reduced the odds of survival by 50%.
‘As therapy for breast cancer becomes more targeted, and researchers come closer to identifying those factors that make some breast cancers more aggressive than others, we may have the option of recommending second, and even third lumpectomies in select cases in the future,’ said study co-author Dr Steven Martinez. ‘Until then, mastectomy remains the best option for women experiencing a same-breast recurrence of their breast cancer.’

20.11.2008

More on the subject:
Read all latest stories

Related articles

Photo

News • New imaging agent

HER2-positive breast cancer: Whole-body PET/CT predicts targeted therapy response

A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.

Photo

Article • Radioembolization

Breast cancer metastasis: benefits and limitations of trans-arterial therapy

Evidence that radioembolization, a trans-arterial therapy, is safe and stops disease progression in metastatic breast cancer is increasing, a prominent American interventional radiologist showed at…

Photo

Article • Promising approach

Focused ultrasound ablation for treatment of breast tumours

Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.

Related products

Subscribe to Newsletter