Technique comparison

Contrast-enhanced digital mammography vs. breast MRI

Contrast-enhanced digital mammography is comparable to breast MRI in evaluating residual breast cancer after neoadjuvant endocrine therapy or chemotherapy, according to the results of a study presented by Mayo Clinic researchers at the 2017 San Antonio Breast Cancer Symposium.

“Our study aimed to compare contrast-enhanced mammography with breast MRI in evaluating residual breast cancer in patients undergoing presurgical systemic treatment to shrink their tumor size,” says Bhavika Patel, M.D., a radiologist at Mayo Clinic's Arizona campus. “We identified patients who had both contrast-enhanced digital mammography and MRI after treatment to shrink their tumors and before additional therapy or a mastectomy.”

Photo
Source: panthermedia.net/monkeybusiness

Dr. Patel and her colleagues conducted a retrospective review of contrast-enhanced digital mammography cases at Mayo Clinic's Arizona campus between September 2014 and June 2016. Forty female patients met inclusion criteria. The mean age of study participants was 52.3 years. Thirty-four patients received chemotherapy, and six patients received endocrine therapy. Researchers interpreted radiographic images in a blinded fashion and compared residual size on imaging to pathology from surgical samples. Their results indicated that both imaging modalities demonstrate comparable accuracy in assessing residual cancer.

Patients find contrast-enhanced digital mammography less anxiety-provoking than MRI

Bhavika Patel

“These findings, if validated in larger studies, could potentially support the use of contrast-enhanced mammography as an alternative approach for evaluating residual cancer in the preoperative setting.” Dr. Patel says contrast-enhanced mammography is a potentially easier, faster, more accessible and more cost-effective option than breast MRI. She says Mayo Clinic's Arizona campus is one of the first sites in the U.S. to implement contrast-enhanced digital mammography. “Patients find contrast-enhanced digital mammography less anxiety-provoking than MRI, which can cause some patients to feel claustrophobic,” Dr. Patel says.


Source: Mayo Clinic

08.12.2017

Read all latest stories

Related articles

Photo

Clinical trial

A simple breath test could evolve breast cancer diagnostics

The University of Southern California (USC) Norris Comprehensive Cancer Center is actively recruiting for a clinical trial that is researching the effectiveness of a breath test for breast cancer…

Photo

New Italian study results

Pre-operative MRI endorsed for breast cancer

MRI offers unequalled sensitivity and specificity in breast cancer detection. Yet, it is poorly accepted preoperatively. Recently, eminent radiologist Francesco Sardanelli, professor for radiology at…

Photo

To-Be for tomo

Two-part trial studies tomosynthesis benefits

The UNESCO World Heritage City Bergen is seen as the gateway to the fiords of Norway. However, for radiologists the city offers an even more interesting attraction than Scandinavian landscapes.…

Related products

Hologic – SecurView Diagnostic Workstations

Mammo Workstation

Hologic – SecurView Diagnostic Workstations

Hologic, Inc.
Agena Bioscience - MassARRAY Colon Panel

Amplification/Detection

Agena Bioscience - MassARRAY Colon Panel

Agena Bioscience GmbH
allMRI GmbH – MRI vacuum immobilisation for head coils

Accessories / Complementary systems

allMRI GmbH – MRI vacuum immobilisation for head coils

allMRI GmbH
allMRI GmbH – MRI wheelchair – foldable

Accessories / Complementary systems

allMRI GmbH – MRI wheelchair – foldable

allMRI GmbH
allMRI GmbH – MRI wheeled waste bin – 90 liters

Accessories / Complementary Systems

allMRI GmbH – MRI wheeled waste bin – 90 liters

allMRI GmbH
Barco – Nio 5MP

Displays – Mammo

Barco – Nio 5MP

Barco NV