Study

Risk factors on rise among people with stroke

Despite prevention efforts, researchers have found a significant increase over a 10-year period in the percentage of people with stroke who have high blood pressure, diabetes, smoking and other risk factors for stroke.

Photo
Source: Pixabay/Myriams-Fotos

“An estimated 80 percent of all first strokes are due to risk factors that can be changed, such as high blood pressure, and many efforts have been made to prevent, screen for and treat these risk factors. Yet we saw a widespread increase in the number of stroke patients with one or more risk factors,” said study author Fadar Oliver Otite, MD, ScM, of the University of Miami Miller School of Medicine and member of the American Academy of Neurology. “These alarming findings support the call for further action to develop more effective methods to prevent and control these risk factors to reduce stroke risk.”

We still have progress to make on preventing stroke and better controlling risk factors

Oliver Otite

For the study, researchers examined a public database of U.S. hospitalizations, and identified 922,451 adult hospitalizations for ischemic stroke between 2004 and 2014. An ischemic stroke is caused by a blockage in a blood vessel, such as a blood clot. Of those stroke cases, 93 percent of people had one or more risk factors, which increased from 88 percent in 2004 to 95 percent in 2014. The prevalence of high cholesterol more than doubled during the study period, from 29 percent to 59 percent. The prevalence of diabetes increased by 22 percent, from 31 percent to 38 percent. The prevalence of high blood pressure increased by 15 percent, from 73 percent to 84 percent. And the prevalence of drug abuse doubled, from 1.4 percent to 2.8 percent. These risk factors varied by age, race and sex.

Researchers found that the incidence of high blood pressure in stroke hospitalizations increased annually by 1 percent, diabetes increased by 2 percent, high cholesterol by 7 percent, smoking by 5 percent and drug abuse by 7 percent. Additionally, kidney failure increased annually by 13 percent, plaque buildup in the carotid artery by 6 percent and coronary artery disease by 1 percent. The proportion of people with multiple risk factors also increased over time.

Photo
Source: Pixabay/StockSnap

While the study did not examine reasons for the increase, researchers say improved screening and detection of some risk factors may have played a role. Otite said, “While we have made great strides in reducing the proportion of people who die from stroke, we still have progress to make on preventing stroke and better controlling these risk factors.”

Limitations of the study include that the definitions of some risk factors may have changed over time and therefore risk factors may not have been recorded consistently. Also, increased prevalence of high cholesterol could be related to more testing being done after studies showed the benefits of statins for stroke prevention.


Source: American Academy of Neurology (AAN)

12.10.2017

Read all latest stories

Related articles

Photo

Alternative to statin treatment

Atherosclerosis: Antibodies stabilise plaque

Researchers at Karolinska Institutet have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilise the plaque that accumulates on…

Photo

Tailored treatment needed

Half of patients on statins fail to reach ‘healthy’ cholesterol level after 2 years

Half of patients prescribed statins in primary care fail to reach ‘healthy’ cholesterol levels after two years of treatment with these drugs, reveals research published online in the journal…

Photo

In situ vaccination

Turning tumors into cancer vaccine factories

Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, injecting immune stimulants directly into a tumor to teach the immune system to destroy it and other tumor cells…